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PLOS Genetics - Číslo 6/2020
Research Article
1008312Nitric oxide mediates neuro-glial interaction that shapes Drosophila circadian behaviorAnatoly Kozlov, Rafael Koch, Emi Nagoshi
1008471Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retrovirusesMelvyn W. Yap, George R. Young, Renata Varnaite, Serge Morand, Jonathan P. Stoye
1008511JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damageJérémie Fages, Catherine Chailleux, Jonathan Humbert, Suk-Min Jang, Jérémy Loehr, Jean-Philippe Lambert, Jacques Côté, Didier Trouche, Yvan Canitrot
1008595Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophaseJohan A. Slotman, Maarten W. Paul, Fabrizia Carofiglio, H. Martijn de Gruiter, Tessa Vergroesen, Lieke Koornneef, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Willy M. Baarends
1008601Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosisSahar Houshdaran, Ashwini B. Oke, Jennifer C. Fung, Kim Chi Vo, Camran Nezhat, Linda C. Giudice
1008622Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascadeJun Xu, Wei Liu, Dehong Yang, Shuqing Chen, Kai Chen, Zulian Liu, Xu Yang, Jing Meng, Guanheng Zhu, Shuanglin Dong, Yong Zhang, Shuai Zhan, Guirong Wang, Yongping Huang
1008715A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5Chalita Washington, Rachel Chernet, Rewatee H. Gokhale, Yesenia Martino-Cortez, Hsiu-Yu Liu, Ashley M. Rosenberg, Sivan Shahar, Cathie M. Pfleger
1008717Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networksCarmen Santa-Cruz Mateos, Andrea Valencia-Expósito, Isabel M. Palacios, María D. Martín-Bermudo
1008725Age-of-onset information helps identify 76 genetic variants associated with allergic diseaseManuel A. R. Ferreira, Judith M. Vonk, Hansjörg Baurecht, Ingo Marenholz, Chao Tian, Joshua D. Hoffman, Quinta Helmer, Annika Tillander, Vilhelmina Ullemar, Yi Lu, Sarah Grosche, Franz Rüschendorf, Raquel Granell, Ben M. Brumpton, Lars G. Fritsche, Laxmi Bhatta, Maiken E. Gabrielsen, Jonas B. Nielsen, Wei Zhou, Kristian Hveem, Arnulf Langhammer, Oddgeir L. Holmen, Mari Løset, Gonçalo R. Abecasis, Cristen J. Willer, Nima C. Emami, Taylor B. Cavazos, John S. Witte, Agnieszka Szwajda, , , David A. Hinds, Norbert Hübner, Stephan Weidinger, Patrik KE Magnusson, Eric Jorgenson, Robert Karlsson, Lavinia Paternoster, Dorret I. Boomsma, Catarina Almqvist, Young-Ae Lee, Gerard H. Koppelman
1008740Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolismDiana C. Odermatt, Wei Ting C. Lee, Sebastian Wild, Stanislaw K. Jozwiakowski, Eli Rothenberg, Kerstin Gari
1008756NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposurePatrick J. Murphy, Jingtao Guo, Timothy G. Jenkins, Emma R. James, John R. Hoidal, Thomas Huecksteadt, Dallin S. Broberg, James M. Hotaling, David F. Alonso, Douglas T. Carrell, Bradley R. Cairns, Kenneth I. Aston
1008774Pax6 organizes the anterior eye segment by guiding two distinct neural crest wavesMasanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D. Weger, Dimitra Margariti, Angel R. Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C. Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
1008775Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathologyNikhil Milind, Christoph Preuss, Annat Haber, Guruprasad Ananda, Shubhabrata Mukherjee, Cai John, Sarah Shapley, Benjamin A. Logsdon, Paul K. Crane, Gregory W. Carter
1008778Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptationsAlyson Sujkowski, Anna Gretzinger, Nicolette Soave, Sokol V. Todi, Robert Wessells
1008788Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune diseaseLiselotte Bäckdahl, Mike Aoun, Ulrika Norin, Rikard Holmdahl
1008790Exclusive breastfeeding can attenuate body-mass-index increase among genetically susceptible children: A longitudinal study from the ALSPAC cohortYanyan Wu, Stephen Lye, Cindy-Lee Dennis, Laurent Briollais
1008792Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during developmentTanzeen Yusuff, Matthew Jensen, Sneha Yennawar, Lucilla Pizzo, Siddharth Karthikeyan, Dagny J. Gould, Avik Sarker, Erika Gedvilaite, Yurika Matsui, Janani Iyer, Zhi-Chun Lai, Santhosh Girirajan
1008799BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1Shu Wu, Yuanlong Ge, Xiaocui Li, Yiding Yang, Haoxian Zhou, Kaixuan Lin, Zepeng Zhang, Yong Zhao
1008803MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progressionTajana Tešan Tomić, Josefin Olausson, Anna Rehammar, Lily Deland, Andreas Muth, Katarina Ejeskär, Staffan Nilsson, Erik Kristiansson, Ola Nilsson Wassén, Frida Abel
1008805Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone massMadison L. Doolittle, Gina M. Calabrese, Larry D. Mesner, Dana A. Godfrey, Robert D. Maynard, Cheryl L. Ackert-Bicknell, Charles R. Farber
1008808In vivo modeling of metastatic human high-grade serous ovarian cancer in miceOlga Kim, Eun Young Park, David L. Klinkebiel, Svetlana D. Pack, Yong-Hyun Shin, Zied Abdullaev, Robert E. Emerson, Donna M. Coffey, Sun Young Kwon, Chad J. Creighton, Sanghoon Kwon, Edmund C. Chang, Theodore Chiang, Alexander N. Yatsenko, Jeremy Chien, Dong-Joo Cheon, Yang Yang-Hartwich, Harikrishna Nakshatri, Kenneth P. Nephew, Richard R. Behringer, Facundo M. Fernández, Chi-Heum Cho, Barbara Vanderhyden, Ronny Drapkin, Robert C. Bast, Jr, Kathy D. Miller, Adam R. Karpf, Jaeyeon Kim
1008810GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiationAnbarasi Kothandapani, Samantha R. Lewis, Jessica L. Noel, Abbey Zacharski, Kyle Krellwitz, Anna Baines, Stephanie Winske, Chad M. Vezina, Elena M. Kaftanovskaya, Alexander I. Agoulnik, Emily M. Merton, Martin J. Cohn, Joan S. Jorgensen
1008814The role of ROC75 as a daytime component of the circadian oscillator in Chlamydomonas reinhardtiiTakuya Matsuo, Takahiro Iida, Ayumi Ohmura, Malavika Gururaj, Daisaku Kato, Risa Mutoh, Kunio Ihara, Masahiro Ishiura
1008822An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposonsGareth D. Weedall, Jacob M. Riveron, Jack Hearn, Helen Irving, Colince Kamdem, Caroline Fouet, Bradley J. White, Charles S. Wondji
1008829BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factorTimothy P. Cheung, Jun-Yong Choe, Janet E. Richmond, Hongkyun Kim
1008830Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3′UTR intron-containing NMD targetsPooja Gangras, Thomas L. Gallagher, Michael A. Parthun, Zhongxia Yi, Robert D. Patton, Kiel T. Tietz, Natalie C. Deans, Ralf Bundschuh, Sharon L. Amacher, Guramrit Singh
1008831Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the fish Betta splendensTrieu-Duc Vu, Yuki Iwasaki, Shuji Shigenobu, Akiko Maruko, Kenshiro Oshima, Erica Iioka, Chao-Li Huang, Takashi Abe, Satoshi Tamaki, Yi-Wen Lin, Chih-Kuan Chen, Mei-Yeh Lu, Masaru Hojo, Hao-Ven Wang, Shun-Fen Tzeng, Hao-Jen Huang, Akio Kanai, Takashi Gojobori, Tzen-Yuh Chiang, H. Sunny Sun, Wen-Hsiung Li, Norihiro Okada
1008836Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscapeXueliang Lyu, Qian Yang, Lin Li, Yunkun Dang, Zhipeng Zhou, She Chen, Yi Liu
1008837Control of mRNA translation by dynamic ribosome modificationLucia Grenga, Richard Howard Little, Govind Chandra, Stuart Daniel Woodcock, Gerhard Saalbach, Richard James Morris, Jacob George Malone
1008838ROS regulation of RAS and vulva development in Caenorhabditis elegansMaximilian Kramer-Drauberg, Ju-Ling Liu, David Desjardins, Ying Wang, Robyn Branicky, Siegfried Hekimi
1008840The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiaeEmma B. Alme, Erica Stevenson, Nevan J. Krogan, Danielle L. Swaney, David P. Toczyski
1008841yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia developmentBernardo Blanco-Sánchez, Aurélie Clément, Sara J. Stednitz, Jennifer Kyle, Judy L. Peirce, Marcie McFadden, Jeremy Wegner, Jennifer B. Phillips, Ellen Macnamara, Yan Huang, David R. Adams, Camilo Toro, William A. Gahl, May Christine V. Malicdan, Cynthia J. Tifft, Erika M. Zink, Kent J. Bloodsworth, Kelly G. Stratton, , David M. Koeller, Thomas O. Metz, Philip Washbourne, Monte Westerfield
1008847Overlapping functions and protein-protein interactions of LRR-extensins in ArabidopsisAline Herger, Shibu Gupta, Gabor Kadler, Christina Maria Franck, Aurélien Boisson-Dernier, Christoph Ringli
1008848Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infectionsJoe J. Harrison, Henrik Almblad, Yasuhiko Irie, Daniel J. Wolter, Heather C. Eggleston, Trevor E. Randall, Jacob O. Kitzman, Bethany Stackhouse, Julia C. Emerson, Sharon Mcnamara, Tyler J. Larsen, Jay Shendure, Lucas R. Hoffman, Daniel J. Wozniak, Matthew R. Parsek
1008849The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plantsHongkuan Wang, Wanyue Xu, Yujin Sun, Qichao Lian, Cong Wang, Chaoyi Yu, Chengpeng He, Jun Wang, Hong Ma, Gregory P. Copenhaver, Yingxiang Wang
1008850Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptationMatt Bawn, Nabil-Fareed Alikhan, Gaëtan Thilliez, Mark Kirkwood, Nicole E. Wheeler, Liljana Petrovska, Timothy J. Dallman, Evelien M. Adriaenssens, Neil Hall, Robert A. Kingsley
1008855Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traitsWei Cheng, Sohini Ramachandran, Lorin Crawford
1008861Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunityLuyang Wang, Daniel A. Barbash, Erin S. Kelleher
1008862A Bayesian method to estimate variant-induced disease penetranceBrett M. Kroncke, Derek K. Smith, Yi Zuo, Andrew M. Glazer, Dan M. Roden, Jeffrey D. Blume
10088631008864Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropodsSamuel H. Lewis, Laura Ross, Stevie A. Bain, Eleni Pahita, Steven A. Smith, Richard Cordaux, Eric A. Miska, Boris Lenhard, Francis M. Jiggins, Peter Sarkies, Stephen A. Smith
1008865Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiaeKoji Kasahara, Risa Nakayama, Yuh Shiwa, Yu Kanesaki, Taichiro Ishige, Hirofumi Yoshikawa, Tetsuro Kokubo
1008866Phylogenetic background and habitat drive the genetic diversification of Escherichia coliMarie Touchon, Amandine Perrin, Jorge André Moura de Sousa, Belinda Vangchhia, Samantha Burn, Claire L. O’Brien, Erick Denamur, David Gordon, Eduardo PC Rocha
1008867VolcanoFinder: Genomic scans for adaptive introgressionDerek Setter, Sylvain Mousset, Xiaoheng Cheng, Rasmus Nielsen, Michael DeGiorgio, Joachim Hermisson
1008868Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunctionChung-Yang Kao, Mafei Xu, Leiming Wang, Shih-Chieh Lin, Hui-Ju Lee, Lita Duraine, Hugo J. Bellen, David S. Goldstein, Sophia Y. Tsai, Ming-Jer Tsai
1008869Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)Ciana Deveau, Xiaodong Jiao, Sachihiro C. Suzuki, Asha Krishnakumar, Takeshi Yoshimatsu, J Fielding Hejtmancik, Ralph F. Nelson
1008873Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signalingFujikura Ushio, Kazune Ezaki, Gorou Horiguchi, Mitsunori Seo, Yuri Kanno, Yuji Kamiya, Michael Lenhard, Hirokazu Tsukaya, Ushio Fujikura
1008877Protein-protein interaction network controlling establishment and maintenance of switchable cell polarityLuís António Menezes Carreira, Filipe Tostevin, Ulrich Gerland, Lotte Søgaard-Andersen
1008881Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processesSelma S. Alkafeef, Shelley Lane, Clinton Yu, Tingting Zhou, Norma V. Solis, Scott G. Filler, Lan Huang, Haoping Liu
1008885Regulation of epithelial integrity and organ growth by Tctp and Coracle in DrosophilaSung-Ryeong Lee, Sung-Tae Hong, Kwang-Wook Choi
1008890The brachyceran de novo gene PIP82, a phosphorylation target of aPKC, is essential for proper formation and maintenance of the rhabdomeric photoreceptor apical domain in DrosophilaAndrew C. Zelhof, Simpla Mahato, Xulong Liang, Jonathan Rylee, Emma Bergh, Lauren E. Feder, Matthew E. Larsen, Steven G. Britt, Markus Friedrich
1008892Reciprocal regulation between nicotinamide adenine dinucleotide metabolism and abscisic acid and stress response pathways in ArabidopsisYechun Hong, Zhen Wang, Huazhong Shi, Juanjuan Yao, Xue Liu, Fuxing Wang, Liang Zeng, Zhi Xie, Jian-Kang Zhu
1008894AXR1 affects DNA methylation independently of its role in regulating meiotic crossover localizationNicolas Christophorou, Wenjing She, Jincheng Long, Aurélie Hurel, Sébastien Beaubiat, Yassir Idir, Marina Tagliaro-Jahns, Aurélie Chambon, Victor Solier, Daniel Vezon, Mathilde Grelon, Xiaoqi Feng, Nicolas Bouché, Christine Mézard
1008897c-di-GMP inhibits LonA-dependent proteolysis of TfoY in Vibrio choleraeAvatar Joshi, Samar A. Mahmoud, Soo-Kyoung Kim, Justyne L. Ogdahl, Vincent T. Lee, Peter Chien, Fitnat H. Yildiz
1008902All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disordersCarson J. Miller, Geum-Yi Kim, Xiaonan Zhao, Karen Usdin
1008905Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophaseRichard Cardoso da Silva, María Ascensión Villar-Fernández, Gerben Vader
Perspective
1008714Osteocalcin promotes bone mineralization but is not a hormoneStavros C. Manolagas
Formal Comment
1008938The facts of the matter: What is a hormone?Gerard Karsenty
1008939Lack of reproducibility in osteocalcin-deficient miceTakeshi Moriishi, Toshihisa Komori
1008940Independent validation of experimental results requires timely and unrestricted access to animal models and reagentsCassandra R. Diegel, Steven Hann, Ugur M. Ayturk, Jennifer C. W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, , Alexander G. Robling, Matthew L. Warman, Bart O. Williams
PLOS Genetics
2020 Číslo 6
Nejčtenější v tomto čísle- Osteocalcin promotes bone mineralization but is not a hormone
- Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism
- Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis
- Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape
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