PLOS Genetics - Číslo 3/2015

Perspective

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Morphological Mutations: Lessons from the Cockscomb

Research Article

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NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module
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Sex Ratio Meiotic Drive as a Plausible Evolutionary Mechanism for Hybrid Male Sterility
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The Class Homeodomain Factors and Cooperate in . Embryonic Progenitor Cells to Regulate Robust Development
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Hyperdiverse Gene Cluster in Snail Host Conveys Resistance to Human Schistosome Parasites
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Glycosyl Phosphatidylinositol Anchor Biosynthesis Is Essential for Maintaining Epithelial Integrity during Embryogenesis
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Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Region
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Escape from X Inactivation Varies in Mouse Tissues
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RECG Maintains Plastid and Mitochondrial Genome Stability by Suppressing Extensive Recombination between Short Dispersed Repeats
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Tertiary siRNAs Mediate Paramutation in .
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Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10
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Synergistic Interactions between Orthologues of Genes Spanned by Human CNVs Support Multiple-Hit Models of Autism
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Complex Genomic Rearrangements at the Locus Include Triplication and Quadruplication
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Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis
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Small Regulatory RNA-Induced Growth Rate Heterogeneity of
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Resistance to Gray Leaf Spot of Maize: Genetic Architecture and Mechanisms Elucidated through Nested Association Mapping and Near-Isogenic Line Analysis
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A Zinc Finger Motif-Containing Protein Is Essential for Chloroplast RNA Editing
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The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes
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The Role of China in the Global Spread of the Current Cholera Pandemic
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Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast
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Recombination between Homologous Chromosomes Induced by Unrepaired UV-Generated DNA Damage Requires Mus81p and Is Suppressed by Mms2p
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Gene Networks Underlying Convergent and Pleiotropic Phenotypes in a Large and Systematically-Phenotyped Cohort with Heterogeneous Developmental Disorders
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Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
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Replicative DNA Polymerase δ but Not ε Proofreads Errors in and in
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Nab3 Facilitates the Function of the TRAMP Complex in RNA Processing via Recruitment of Rrp6 Independent of Nrd1
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A Role for the Budding Yeast Separase, Esp1, in Ty1 Element Retrotransposition
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Network Analyses Reveal Novel Aspects of ALS Pathogenesis
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Pervasive Variation of Transcription Factor Orthologs Contributes to Regulatory Network Evolution
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A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension
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The Small Protein MntS and Exporter MntP Optimize the Intracellular Concentration of Manganese
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Unsaturation of Very-Long-Chain Ceramides Protects Plant from Hypoxia-Induced Damages by Modulating Ethylene Signaling in
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Inhibits Neuromuscular Junction Growth by Downregulating the BMP Receptor Thickveins
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The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes
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Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin
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A Genomic Portrait of Haplotype Diversity and Signatures of Selection in Indigenous Southern African Populations
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Osteopetrorickets due to Snx10 Deficiency in Mice Results from Both Failed Osteoclast Activity and Loss of Gastric Acid-Dependent Calcium Absorption
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Transcriptomic Profiling of Reveals Reprogramming of the Crp Regulon by Temperature and Uncovers Crp as a Master Regulator of Small RNAs
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NatB Domain-Containing CRA-1 Antagonizes Hydrolase ACER-1 Linking Acetyl-CoA Metabolism to the Initiation of Recombination during . Meiosis
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The Complex Contributions of Genetics and Nutrition to Immunity in
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Linking Aβ42-Induced Hyperexcitability to Neurodegeneration, Learning and Motor Deficits, and a Shorter Lifespan in an Alzheimer’s Model
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Combinatorial Control of Light Induced Chromatin Remodeling and Gene Activation in
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A Systems-Level Interrogation Identifies Regulators of Blood Cell Number and Survival
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Ccr4-Not Regulates RNA Polymerase I Transcription and Couples Nutrient Signaling to the Control of Ribosomal RNA Biogenesis
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Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling
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Maternal Filaggrin Mutations Increase the Risk of Atopic Dermatitis in Children: An Effect Independent of Mutation Inheritance
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The Fun30 Chromatin Remodeler Fft3 Controls Nuclear Organization and Chromatin Structure of Insulators and Subtelomeres in Fission Yeast
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Seizures Are Regulated by Ubiquitin-specific Peptidase 9 X-linked (USP9X), a De-Ubiquitinase
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BREVIPEDICELLUS Interacts with the SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA to Regulate and Expression in Control of Inflorescence Architecture
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Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat
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HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice
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Clonality and Evolutionary History of Rhabdomyosarcoma
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Inhibition of Telomere Recombination by Inactivation of KEOPS Subunit Cgi121 Promotes Cell Longevity
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Maternal Co-ordinate Gene Regulation and Axis Polarity in the Scuttle Fly
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Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction
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Methyl Farnesoate Plays a Dual Role in Regulating Metamorphosis
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The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in
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Rapid Evolution of Recombinant for Xylose Fermentation through Formation of Extra-chromosomal Circular DNA
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Genome-Wide Association Studies in Dogs and Humans Identify as a Risk Variant for Cleft Lip and Palate
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Exome Sequencing in an Admixed Isolated Population Indicates Variants Confer a Risk for Specific Language Impairment
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Mutations of Human , Encoding the Mitochondrial Asparaginyl-tRNA Synthetase, Cause Nonsyndromic Deafness and Leigh Syndrome
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Genome-wide Association Study and Meta-Analysis Identify as Genome-wide Significant Susceptibility Gene for Bladder Exstrophy
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A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes
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A Cascade of Iron-Containing Proteins Governs the Genetic Iron Starvation Response to Promote Iron Uptake and Inhibit Iron Storage in Fission Yeast
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LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility
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Neurospora Importin α Is Required for Normal Heterochromatic Formation and DNA Methylation
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Systems Biology of Tissue-Specific Response to Reveals Differentiated Apoptosis in the Tick Vector
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GAGA Factor Maintains Nucleosome-Free Regions and Has a Role in RNA Polymerase II Recruitment to Promoters
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Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3
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Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus
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DNA Polymerase ζ-Dependent Lesion Bypass in Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA
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PHABULOSA Controls the Quiescent Center-Independent Root Meristem Activities in
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The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors
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Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling
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The Contribution of Alu Elements to Mutagenic DNA Double-Strand Break Repair
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Cis-Regulatory Mechanisms for Robust Olfactory Sensory Neuron Class-restricted Odorant Receptor Gene Expression in
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Reproductive Isolation of Hybrid Populations Driven by Genetic Incompatibilities
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Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics
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The GATA Factor Regulates . Developmental Timing by Promoting Expression of the Family MicroRNAs
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Bacterial Infection Drives the Expression Dynamics of microRNAs and Their isomiRs
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Selective and Genetic Constraints on Pneumococcal Serotype Switching
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A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex
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HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy
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Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown
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A RecA Protein Surface Required for Activation of DNA Polymerase V

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