PLOS Genetics - Číslo 3/2015

Perspective

32767
Morphological Mutations: Lessons from the Cockscomb

Research Article

32767
NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module
Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling
A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes
Genome-wide Association Study and Meta-Analysis Identify as Genome-wide Significant Susceptibility Gene for Bladder Exstrophy
Mutations of Human , Encoding the Mitochondrial Asparaginyl-tRNA Synthetase, Cause Nonsyndromic Deafness and Leigh Syndrome
Exome Sequencing in an Admixed Isolated Population Indicates Variants Confer a Risk for Specific Language Impairment
Genome-Wide Association Studies in Dogs and Humans Identify as a Risk Variant for Cleft Lip and Palate
Rapid Evolution of Recombinant for Xylose Fermentation through Formation of Extra-chromosomal Circular DNA
The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in
Methyl Farnesoate Plays a Dual Role in Regulating Metamorphosis
Maternal Co-ordinate Gene Regulation and Axis Polarity in the Scuttle Fly
Maternal Filaggrin Mutations Increase the Risk of Atopic Dermatitis in Children: An Effect Independent of Mutation Inheritance
Inhibition of Telomere Recombination by Inactivation of KEOPS Subunit Cgi121 Promotes Cell Longevity
Clonality and Evolutionary History of Rhabdomyosarcoma
HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice
Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat
BREVIPEDICELLUS Interacts with the SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA to Regulate and Expression in Control of Inflorescence Architecture
Seizures Are Regulated by Ubiquitin-specific Peptidase 9 X-linked (USP9X), a De-Ubiquitinase
The Fun30 Chromatin Remodeler Fft3 Controls Nuclear Organization and Chromatin Structure of Insulators and Subtelomeres in Fission Yeast
A Cascade of Iron-Containing Proteins Governs the Genetic Iron Starvation Response to Promote Iron Uptake and Inhibit Iron Storage in Fission Yeast
Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction
LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility
Cis-Regulatory Mechanisms for Robust Olfactory Sensory Neuron Class-restricted Odorant Receptor Gene Expression in
Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown
HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy
A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex
Selective and Genetic Constraints on Pneumococcal Serotype Switching
Bacterial Infection Drives the Expression Dynamics of microRNAs and Their isomiRs
The GATA Factor Regulates . Developmental Timing by Promoting Expression of the Family MicroRNAs
Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics
Reproductive Isolation of Hybrid Populations Driven by Genetic Incompatibilities
The Contribution of Alu Elements to Mutagenic DNA Double-Strand Break Repair
Systems Biology of Tissue-Specific Response to Reveals Differentiated Apoptosis in the Tick Vector
Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling
The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors
PHABULOSA Controls the Quiescent Center-Independent Root Meristem Activities in
DNA Polymerase ζ-Dependent Lesion Bypass in Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA
Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus
Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3
GAGA Factor Maintains Nucleosome-Free Regions and Has a Role in RNA Polymerase II Recruitment to Promoters
Neurospora Importin α Is Required for Normal Heterochromatic Formation and DNA Methylation
Ccr4-Not Regulates RNA Polymerase I Transcription and Couples Nutrient Signaling to the Control of Ribosomal RNA Biogenesis
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
A Systems-Level Interrogation Identifies Regulators of Blood Cell Number and Survival
Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast
The Role of China in the Global Spread of the Current Cholera Pandemic
The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes
A Zinc Finger Motif-Containing Protein Is Essential for Chloroplast RNA Editing
Resistance to Gray Leaf Spot of Maize: Genetic Architecture and Mechanisms Elucidated through Nested Association Mapping and Near-Isogenic Line Analysis
Small Regulatory RNA-Induced Growth Rate Heterogeneity of
Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis
Complex Genomic Rearrangements at the Locus Include Triplication and Quadruplication
Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10
Sex Ratio Meiotic Drive as a Plausible Evolutionary Mechanism for Hybrid Male Sterility
Tertiary siRNAs Mediate Paramutation in .
RECG Maintains Plastid and Mitochondrial Genome Stability by Suppressing Extensive Recombination between Short Dispersed Repeats
Escape from X Inactivation Varies in Mouse Tissues
Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Region
Glycosyl Phosphatidylinositol Anchor Biosynthesis Is Essential for Maintaining Epithelial Integrity during Embryogenesis
Hyperdiverse Gene Cluster in Snail Host Conveys Resistance to Human Schistosome Parasites
The Class Homeodomain Factors and Cooperate in . Embryonic Progenitor Cells to Regulate Robust Development
Recombination between Homologous Chromosomes Induced by Unrepaired UV-Generated DNA Damage Requires Mus81p and Is Suppressed by Mms2p
Synergistic Interactions between Orthologues of Genes Spanned by Human CNVs Support Multiple-Hit Models of Autism
Gene Networks Underlying Convergent and Pleiotropic Phenotypes in a Large and Systematically-Phenotyped Cohort with Heterogeneous Developmental Disorders
The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes
Combinatorial Control of Light Induced Chromatin Remodeling and Gene Activation in
Linking Aβ42-Induced Hyperexcitability to Neurodegeneration, Learning and Motor Deficits, and a Shorter Lifespan in an Alzheimer’s Model
The Complex Contributions of Genetics and Nutrition to Immunity in
NatB Domain-Containing CRA-1 Antagonizes Hydrolase ACER-1 Linking Acetyl-CoA Metabolism to the Initiation of Recombination during . Meiosis
Transcriptomic Profiling of Reveals Reprogramming of the Crp Regulon by Temperature and Uncovers Crp as a Master Regulator of Small RNAs
Osteopetrorickets due to Snx10 Deficiency in Mice Results from Both Failed Osteoclast Activity and Loss of Gastric Acid-Dependent Calcium Absorption
A Genomic Portrait of Haplotype Diversity and Signatures of Selection in Indigenous Southern African Populations
Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin
Inhibits Neuromuscular Junction Growth by Downregulating the BMP Receptor Thickveins
Replicative DNA Polymerase δ but Not ε Proofreads Errors in and in
Unsaturation of Very-Long-Chain Ceramides Protects Plant from Hypoxia-Induced Damages by Modulating Ethylene Signaling in
The Small Protein MntS and Exporter MntP Optimize the Intracellular Concentration of Manganese
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension
Pervasive Variation of Transcription Factor Orthologs Contributes to Regulatory Network Evolution
Network Analyses Reveal Novel Aspects of ALS Pathogenesis
A Role for the Budding Yeast Separase, Esp1, in Ty1 Element Retrotransposition
Nab3 Facilitates the Function of the TRAMP Complex in RNA Processing via Recruitment of Rrp6 Independent of Nrd1
A RecA Protein Surface Required for Activation of DNA Polymerase V

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