PLOS Genetics - Číslo 7/2014

Research Article

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Cuba: Exploring the History of Admixture and the Genetic Basis of Pigmentation Using Autosomal and Uniparental Markers
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A Novel Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach
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Apomictic and Sexual Germline Development Differ with Respect to Cell Cycle, Transcriptional, Hormonal and Epigenetic Regulation
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Functional EF-Hands in Neuronal Calcium Sensor GCAP2 Determine Its Phosphorylation State and Subcellular Distribution , and Are Essential for Photoreceptor Cell Integrity
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Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data
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Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age
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Cis and Trans Effects of Human Genomic Variants on Gene Expression
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8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage
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Novel Approach Identifies SNPs in and with Evidence for Parent-of-Origin Effect on Body Mass Index
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Hypoxia Adaptations in the Grey Wolf () from Qinghai-Tibet Plateau
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A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis
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Unraveling Genetic Modifiers in the Mouse Model of Absence Epilepsy
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DNA Topoisomerase 1α Promotes Transcriptional Silencing of Transposable Elements through DNA Methylation and Histone Lysine 9 Dimethylation in
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The Coding and Noncoding Architecture of the Genome
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Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine
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Genome Wide Association Identifies Common Variants at the Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
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The PTK7-Related Transmembrane Proteins Off-track and Off-track 2 Are Co-receptors for Wnt2 Required for Male Fertility
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The Co-factor of LIM Domains (CLIM/LDB/NLI) Maintains Basal Mammary Epithelial Stem Cells and Promotes Breast Tumorigenesis
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Essential Genetic Interactors of Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates
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Meiosis-Specific Cohesin Component, Is Essential for Maintaining Centromere Chromatid Cohesion, and Required for DNA Repair and Synapsis between Homologous Chromosomes
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Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2
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The Two Cis-Acting Sites, and , Contribute to the Longitudinal Organisation of Chromosome I
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A Broadly Conserved G-Protein-Coupled Receptor Kinase Phosphorylation Mechanism Controls Smoothened Activity
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Requirements for Acute Burn and Chronic Surgical Wound Infection
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LIN-42, the PERIOD homolog, Negatively Regulates MicroRNA Transcription
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WAPL Is Essential for the Prophase Removal of Cohesin during Meiosis
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Expression in Planarian Neoblasts after Injury Controls Anterior Pole Regeneration
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Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis
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Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival
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Stage-Dependent and Locus-Specific Role of Histone Demethylase Jumonji D3 (JMJD3) in the Embryonic Stages of Lung Development
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Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing
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Determinative Developmental Cell Lineages Are Robust to Cell Deaths
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Mechanisms of Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis
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Nucleosomes Shape DNA Polymorphism and Divergence
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Functional Diversification of Hsp40: Distinct J-Protein Functional Requirements for Two Prions Allow for Chaperone-Dependent Prion Selection
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Comparative Phylogenomics Uncovers the Impact of Symbiotic Associations on Host Genome Evolution
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Activation of the Immune System by Combinations of Common Alleles
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Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility
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Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy
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MDRL lncRNA Regulates the Processing of miR-484 Primary Transcript by Targeting miR-361
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Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling
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Intrapopulation Genome Size Variation in Reflects Life History Variation and Plasticity
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SlmA Antagonism of FtsZ Assembly Employs a Two-pronged Mechanism like MinCD
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Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
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DELLA Protein Degradation Is Controlled by a Type-One Protein Phosphatase, TOPP4
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An ARID Domain-Containing Protein within Nuclear Bodies Is Required for Sperm Cell Formation in
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Wnt Signaling Interacts with Bmp and Edn1 to Regulate Dorsal-Ventral Patterning and Growth of the Craniofacial Skeleton
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Common Transcriptional Mechanisms for Visual Photoreceptor Cell Differentiation among Pancrustaceans
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UVB Induces a Genome-Wide Acting Negative Regulatory Mechanism That Operates at the Level of Transcription Initiation in Human Cells
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The Nesprin Family Member ANC-1 Regulates Synapse Formation and Axon Termination by Functioning in a Pathway with RPM-1 and β-Catenin
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Combinatorial Interactions Are Required for the Efficient Recruitment of Pho Repressive Complex (PhoRC) to Polycomb Response Elements
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Recombination in the Human Pseudoautosomal Region PAR1
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Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes
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An Intronic microRNA Links Rb/E2F and EGFR Signaling
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An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding
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Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
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The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent Mutation
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Evolution and Genetic Architecture of Chromatin Accessibility and Function in Yeast
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Accumulation of a Threonine Biosynthetic Intermediate Attenuates General Amino Acid Control by Accelerating Degradation of Gcn4 via Pho85 and Cdk8

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