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PLOS Genetics - Číslo 7/2014

Research Article

32767
Cuba: Exploring the History of Admixture and the Genetic Basis of Pigmentation Using Autosomal and Uniparental Markers
Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing
Mechanisms of Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis
Nucleosomes Shape DNA Polymorphism and Divergence
Functional Diversification of Hsp40: Distinct J-Protein Functional Requirements for Two Prions Allow for Chaperone-Dependent Prion Selection
Comparative Phylogenomics Uncovers the Impact of Symbiotic Associations on Host Genome Evolution
Activation of the Immune System by Combinations of Common Alleles
Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility
Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy
MDRL lncRNA Regulates the Processing of miR-484 Primary Transcript by Targeting miR-361
Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling
Intrapopulation Genome Size Variation in Reflects Life History Variation and Plasticity
SlmA Antagonism of FtsZ Assembly Employs a Two-pronged Mechanism like MinCD
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
Determinative Developmental Cell Lineages Are Robust to Cell Deaths
DELLA Protein Degradation Is Controlled by a Type-One Protein Phosphatase, TOPP4
Wnt Signaling Interacts with Bmp and Edn1 to Regulate Dorsal-Ventral Patterning and Growth of the Craniofacial Skeleton
Common Transcriptional Mechanisms for Visual Photoreceptor Cell Differentiation among Pancrustaceans
UVB Induces a Genome-Wide Acting Negative Regulatory Mechanism That Operates at the Level of Transcription Initiation in Human Cells
The Nesprin Family Member ANC-1 Regulates Synapse Formation and Axon Termination by Functioning in a Pathway with RPM-1 and β-Catenin
Combinatorial Interactions Are Required for the Efficient Recruitment of Pho Repressive Complex (PhoRC) to Polycomb Response Elements
Recombination in the Human Pseudoautosomal Region PAR1
Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes
An Intronic microRNA Links Rb/E2F and EGFR Signaling
An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent Mutation
Evolution and Genetic Architecture of Chromatin Accessibility and Function in Yeast
An ARID Domain-Containing Protein within Nuclear Bodies Is Required for Sperm Cell Formation in
Stage-Dependent and Locus-Specific Role of Histone Demethylase Jumonji D3 (JMJD3) in the Embryonic Stages of Lung Development
Genome Wide Association Identifies Common Variants at the Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival
Apomictic and Sexual Germline Development Differ with Respect to Cell Cycle, Transcriptional, Hormonal and Epigenetic Regulation
Functional EF-Hands in Neuronal Calcium Sensor GCAP2 Determine Its Phosphorylation State and Subcellular Distribution , and Are Essential for Photoreceptor Cell Integrity
Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data
Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age
Cis and Trans Effects of Human Genomic Variants on Gene Expression
8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage
Novel Approach Identifies SNPs in and with Evidence for Parent-of-Origin Effect on Body Mass Index
Hypoxia Adaptations in the Grey Wolf () from Qinghai-Tibet Plateau
A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis
Unraveling Genetic Modifiers in the Mouse Model of Absence Epilepsy
DNA Topoisomerase 1α Promotes Transcriptional Silencing of Transposable Elements through DNA Methylation and Histone Lysine 9 Dimethylation in
The Coding and Noncoding Architecture of the Genome
A Novel Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach
Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine
The PTK7-Related Transmembrane Proteins Off-track and Off-track 2 Are Co-receptors for Wnt2 Required for Male Fertility
The Co-factor of LIM Domains (CLIM/LDB/NLI) Maintains Basal Mammary Epithelial Stem Cells and Promotes Breast Tumorigenesis
Essential Genetic Interactors of Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates
Meiosis-Specific Cohesin Component, Is Essential for Maintaining Centromere Chromatid Cohesion, and Required for DNA Repair and Synapsis between Homologous Chromosomes
Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2
The Two Cis-Acting Sites, and , Contribute to the Longitudinal Organisation of Chromosome I
A Broadly Conserved G-Protein-Coupled Receptor Kinase Phosphorylation Mechanism Controls Smoothened Activity
Requirements for Acute Burn and Chronic Surgical Wound Infection
LIN-42, the PERIOD homolog, Negatively Regulates MicroRNA Transcription
WAPL Is Essential for the Prophase Removal of Cohesin during Meiosis
Expression in Planarian Neoblasts after Injury Controls Anterior Pole Regeneration
Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis
Accumulation of a Threonine Biosynthetic Intermediate Attenuates General Amino Acid Control by Accelerating Degradation of Gcn4 via Pho85 and Cdk8

PLOS Genetics

2014 Číslo 7
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