Drug-induced changes and disorders of sleep and wake cycles – a narrative review

Česká verze

Authors: K. Šonka ¹; M. Pretl ²; K. Seltenreichová ³; J. Slonková ⁴; J. Bušková ^5,6; S. Dostálová ¹
Authors place of work: Neurologická klinika a Centrum klinických neurověd 1. LF UK a VFN v Praze ¹; Inspamed, Praha ²; Neurologické oddělení Nemocnice Na Homolce, Praha ³; Neurologická klinika LF OU a FN Ostrava ⁴; Národní ústav duše ⁵
Published in the journal: Cesk Slov Neurol N 2025; 88(3): 143-152
Category: Minimonografie
doi: https://doi.org/10.48095/cccsnn2022143

Summary

Sleep and wake cycle changes are common adverse effects of medications and can be classified into nosological groups of insomnia, hypersomnolence, sleep-related breathing disorders, parasomnias, and sleep-related movement disorders according to the International Classification of Sleep Disorders, 3^rd edition, Text Revision. This review article enumerates which medications can induce sleep-wake cycle abnormalities and diseases and outlines how these adverse effects occur.

Keywords:

sleep – pharmacodynamics – adverse drug reaction – wake

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