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Drug-induced changes and disorders of sleep and wake cycles – a narrative review


Authors: K. Šonka 1;  M. Pretl 2;  K. Seltenreichová 3;  J. Slonková 4;  J. Bušková 5,6;  S. Dostálová 1
Authors place of work: Neurologická klinika a Centrum klinických neurověd 1. LF UK a VFN v Praze 1;  Inspamed, Praha 2;  Neurologické oddělení Nemocnice Na Homolce, Praha 3;  Neurologická klinika LF OU a FN Ostrava 4;  Národní ústav duševního zdraví, Klecany 5;  3. LF UK, Praha 6
Published in the journal: Cesk Slov Neurol N 2025; 88(3): 143-152
Category: Minimonografie
doi: https://doi.org/10.48095/cccsnn2022143

Summary

Sleep and wake cycle changes are common adverse effects of medications and can be classified into nosological groups of insomnia, hypersomnolence, sleep-related breathing disorders, parasomnias, and sleep-related movement disorders according to the International Classification of Sleep Disorders, 3rd edition, Text Revision. This review article enumerates which medications can induce sleep-wake cycle abnormalities and diseases and outlines how these adverse effects occur.

Keywords:

sleep – pharmacodynamics – adverse drug reaction – wake


Zdroje

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