PLOS Pathogens - Číslo 1/2015


The Importance of Pathogen Load


Implication of Gut Microbiota in Nonalcoholic Fatty Liver Disease
Infections in Humans and Animals: Pathophysiology, Detection, and Treatment
Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis
An Iron-Mimicking, Trojan Horse-Entering Fungi—Has the Time Come for Molecular Imaging of Fungal Infections?
The Shear Stress of Host Cell Invasion: Exploring the Role of Biomolecular Complexes
Virus-Induced NETs – Critical Component of Host Defense or Pathogenic Mediator?


: Trypanosomatids Adapted to Plant Environments
Bacterial Flagella: Twist and Stick, or Dodge across the Kingdoms

Research Article

The M3 Muscarinic Receptor Is Required for Optimal Adaptive Immunity to Helminth and Bacterial Infection
Modulates the Unfolded Protein Response in during Infection
Differential Reliance on Autophagy for Protection from HSV Encephalitis between Newborns and Adults
Identification of HNRNPK as Regulator of Hepatitis C Virus Particle Production
Parasite Biomass-Related Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Vivax Malaria
Early Virus-Host Interactions Dictate the Course of a Persistent Infection
TLR3 Signaling in Macrophages Is Indispensable for the Protective Immunity of Invariant Natural Killer T Cells against Enterovirus 71 Infection
The Epstein-Barr Virus Encoded BART miRNAs Potentiate Tumor Growth
Macrophage-Derived Human Resistin Is Induced in Multiple Helminth Infections and Promotes Inflammatory Monocytes and Increased Parasite Burden
Dissemination of a Highly Virulent Pathogen: Tracking The Early Events That Define Infection
Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization
The Molecular Basis for Control of ETEC Enterotoxin Expression in Response to Environment and Host
Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry
Secreted Herpes Simplex Virus-2 Glycoprotein G Modifies NGF-TrkA Signaling to Attract Free Nerve Endings to the Site of Infection
Preferential Use of Central Metabolism Reveals a Nutritional Basis for Polymicrobial Infection
A New Family of Secreted Toxins in Pathogenic Neisseria Species
A Human Type 5 Adenovirus-Based Therapeutic Vaccine Re-programs Immune Response and Reverses Chronic Cardiomyopathy
Regulation of Oncogene Expression in T-DNA-Transformed Host Plant Cells
GITR Intrinsically Sustains Early Type 1 and Late Follicular Helper CD4 T Cell Accumulation to Control a Chronic Viral Infection
Cell Cycle-Independent Phospho-Regulation of Fkh2 during Hyphal Growth Regulates Pathogenesis
Environmental Drivers of the Spatiotemporal Dynamics of Respiratory Syncytial Virus in the United States
Protective Efficacy of Centralized and Polyvalent Envelope Immunogens in an Attenuated Equine Lentivirus Vaccine
Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 Recipients
Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling
Dengue Virus RNA Structure Specialization Facilitates Host Adaptation
DNA Is an Antimicrobial Component of Neutrophil Extracellular Traps
Uropathogenic Superinfection Enhances the Severity of Mouse Bladder Infection
Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties
The Phylogenetically-Related Pattern Recognition Receptors EFR and XA21 Recruit Similar Immune Signaling Components in Monocots and Dicots
Reprogramming of from Virulent to Persistent Mode Revealed by Complex RNA-seq Analysis
Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection
Elucidation of the RamA Regulon in Reveals a Role in LPS Regulation
IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Challenge
Chronic Filarial Infection Provides Protection against Bacterial Sepsis by Functionally Reprogramming Macrophages
Specificity and Dynamics of Effector and Memory CD8 T Cell Responses in Human Tick-Borne Encephalitis Virus Infection
Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1
Viral Activation of MK2-hsp27-p115RhoGEF-RhoA Signaling Axis Causes Cytoskeletal Rearrangements, P-body Disruption and ARE-mRNA Stabilization

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