PLOS Genetics - Číslo 7/2012

Perspective

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Oocyte Family Trees: Old Branches or New Stems?
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Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo

Editorial

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Guidelines for Genome-Wide Association Studies

Review

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Genomic Data Reveal a Complex Making of Humans

Research Article

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Functional Evolution of Mammalian Odorant Receptors
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Evidence of Inbreeding Depression on Human Height
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Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways
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Role of Architecture in the Function and Specificity of Two Notch-Regulated Transcriptional Enhancer Modules
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Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
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A Regulatory Loop Involving PAX6, MITF, and WNT Signaling Controls Retinal Pigment Epithelium Development
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The Three Faces of Riboviral Spontaneous Mutation: Spectrum, Mode of Genome Replication, and Mutation Rate
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A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
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The Role of Rice HEI10 in the Formation of Meiotic Crossovers
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A Trans-Species Missense SNP in Is Associated with Sex Determination in the Tiger Pufferfish, (Fugu)
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Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk
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Comparative Genomics of Plant-Associated spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions
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The HEI10 Is a New ZMM Protein Related to Zip3
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Detecting Individual Sites Subject to Episodic Diversifying Selection
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Regulates Rhodopsin-1 Metabolism and Is Required for Photoreceptor Neuron Survival
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Identification of Chromatin-Associated Regulators of MSL Complex Targeting in Dosage Compensation
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Three Dopamine Pathways Induce Aversive Odor Memories with Different Stability
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TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in
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Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression
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The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of RNA
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Histone H2B Monoubiquitination Facilitates the Rapid Modulation of Gene Expression during Arabidopsis Photomorphogenesis
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Cellular Variability of RpoS Expression Underlies Subpopulation Activation of an Integrative and Conjugative Element
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Genetic Variants in , , and Influence Male Recombination in Cattle
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The SCF Ubiquitin E3 Ligase Ubiquitylates Sir4 and Functions in Transcriptional Silencing
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Pregnancy-Induced Noncoding RNA () Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation
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Allelic Heterogeneity and Trade-Off Shape Natural Variation for Response to Soil Micronutrient
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Large-Scale Introgression Shapes the Evolution of the Mating-Type Chromosomes of the Filamentous Ascomycete
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GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers
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DNA Methyltransferases Are Required to Induce Heterochromatic Re-Replication in Arabidopsis
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Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP
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The Secreted Immunoglobulin Domain Proteins ZIG-5 and ZIG-8 Cooperate with L1CAM/SAX-7 to Maintain Nervous System Integrity
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RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors
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Gene Conversion Occurs within the Mating-Type Locus of during Sexual Reproduction
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The Chicken Frizzle Feather Is Due to an α-Keratin () Mutation That Causes a Defective Rachis
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Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the Locus
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Balancing Selection at the Tomato Guardee Gene Family Maintains Variation in Strength of Pathogen Defense
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OSD1 Promotes Meiotic Progression via APC/C Inhibition and Forms a Regulatory Network with TDM and CYCA1;2/TAM
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Recent Loss of Self-Incompatibility by Degradation of the Male Component in Allotetraploid
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Intact p53-Dependent Responses in miR-34–Deficient Mice
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FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response
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CED-10/Rac1 Regulates Endocytic Recycling through the RAB-5 GAP TBC-2
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Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity
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F-Box Protein Specificity for G1 Cyclins Is Dictated by Subcellular Localization
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The Gene Encodes a Nuclear Protein That Affects Alternative Splicing
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A Key Role for Chd1 in Histone H3 Dynamics at the 3′ Ends of Long Genes in Yeast
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Genome-Wide Association Analysis in Asthma Subjects Identifies as a Novel Bronchodilator Response Gene
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GRHL3/GET1 and Trithorax Group Members Collaborate to Activate the Epidermal Progenitor Differentiation Program
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Brain-Specific Rescue of Reveals System-Driven Transcriptional Rhythms in Peripheral Tissue
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Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of

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