Advances in clinical trial design: Weaving tomorrow’s TB treatments

Autoři: Christian Lienhardt aff001;  Andrew Nunn aff002;  Richard Chaisson aff003;  Andrew A. Vernon aff004;  Matteo Zignol aff005;  Payam Nahid aff006;  Eric Delaporte aff001;  Tereza Kasaeva aff005
Působiště autorů: Unité Mixte Internationale TransVIHMI, UMI 233 IRD–U1175 INSERM—Université de Montpellier, Institut de Recherche pour le Développement (IRD), Montpellier, France aff001;  MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, United Kingdom aff002;  Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, United States of America aff003;  Division of TB Elimination, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America aff004;  Global TB Programme, World Health Organization, Geneva, Switzerland aff005;  UCSF Center for Tuberculosis and Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, California, United States of America aff006
Vyšlo v časopise: Advances in clinical trial design: Weaving tomorrow’s TB treatments. PLoS Med 17(2): e1003059. doi:10.1371/journal.pmed.1003059
Kategorie: Collection Review
doi: 10.1371/journal.pmed.1003059


Christian Lienhardt and co-authors discuss the conclusions of the PLOS Medicine Collection on advances in clinical trial design for development of new tuberculosis treatments.

Klíčová slova:

Clinical trials – Drug research and development – Drug therapy – Extensively drug-resistant tuberculosis – HIV infections – Phase II clinical investigation – Phase III clinical investigation – Tuberculosis


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