PLOS Genetics - Číslo 11/2011

Perspective

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De Novo Origins of Human Genes
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For Male , Sperm Activation Is a “Just-in-Time” Event

Research Article

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Duplication Hotspots Are Associated with Late-Replicating Regions of the Genome
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The Gene Contains Hotspots for L1 Endonuclease-Dependent Insertion
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Recessive Antimorphic Alleles Overcome Functionally Redundant Loci to Reveal Function in Flowers and Meristems
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Over-Expression of DSCAM and COL6A2 Cooperatively Generates Congenital Heart Defects
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Consequences of Eukaryotic Enhancer Architecture for Gene Expression Dynamics, Development, and Fitness
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Distinct Genetic Architectures for Male and Female Inflorescence Traits of Maize
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Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling
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PcG Complexes Set the Stage for Epigenetic Inheritance of Gene Silencing in Early S Phase before Replication
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Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes
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SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression
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Multiple Means to the Same End: The Genetic Basis of Acquired Stress Resistance in Yeast
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Genome-Wide Crossover Distribution in Meiosis Reveals Sex-Specific Patterns along Chromosomes
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TRY-5 Is a Sperm-Activating Protease in Seminal Fluid
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Homologs of Retinoblastoma-Associated Protein 46/48 Associate with a Histone Deacetylase to Act Redundantly in Chromatin Silencing
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Genetic Interaction Maps in Reveal Functional Crosstalk among Cell Envelope Biogenesis Pathways
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The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications
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from the Aphid : A Missing Link from Facultative to Obligate Insect Endosymbiont
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Pch2 Acts through Xrs2 and Tel1/ATM to Modulate Interhomolog Bias and Checkpoint Function during Meiosis
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De Novo Origin of Human Protein-Coding Genes
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Heritable Epigenetic Variation among Maize Inbreds
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Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells
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Short Day–Mediated Cessation of Growth Requires the Downregulation of AINTEGUMENTALIKE1 Transcription Factor in Hybrid Aspen
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Physiological IRE-1-XBP-1 and PEK-1 Signaling in Larval Development and Immunity
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Role of Pirh2 in Mediating the Regulation of p53 and c-Myc
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Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution
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FOXO Regulates Organ-Specific Phenotypic Plasticity In
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Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence
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Effect of Host Species on the Distribution of Mutational Fitness Effects for an RNA Virus
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Attenuation of the Sensing Capabilities of PhoQ in Transition to Obligate Insect–Bacterial Association
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A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened
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Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in -Induced Senescence
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Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks
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The SUN Protein Mps3 Is Required for Spindle Pole Body Insertion into the Nuclear Membrane and Nuclear Envelope Homeostasis
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Evidence-Based Annotation of Gene Function in MR-1 Using Genome-Wide Fitness Profiling across 121 Conditions
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PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

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