Workflow for bioprinting of cell-ladem bioink


Autoři: Sebastian Allig ;  Margot Mayer ;  Christiane Thieleman
Působiště autorů: BioMEMS Lab, Faculty of Engineering, University of Applied Sciences Aschaffenburg, Germany
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 2, 2018, 48, 46-51
Kategorie: Original research

Souhrn

Applying technologies of additive manufacturing to the field of tissue engineering created a pioneering new approach to model complex cell systems artificially. Regarding its huge potential, bioprinting is still in its infancies and many questions are still unanswered. To address this issue, an extrusion-based bioprinting (EBB) process was used to deposit human embryonic kidney (HEK) cells in a defined pattern. It was shown that the bioprinted construct featured a high degree in viability reaching up to 77% 10 days after printing (DAP). This work displays a proof of principle for a controlled cell formation which shall later be applied to in vitro drug screening tests using various types of cells.

Keywords:

Extrusion-based bioprinting, bioink, tissue engineering, in vitro cell systems


Zdroje
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Biomedicína
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