Renal involvement of a patient with Crohn´s disease: A case report

Česká verze

Authors: Olga Snížková ¹; Eva Jančová ²; Eva Honsová ¹
Authors place of work: AeskuLab Patologie k. s. Praha ¹; Klinika nefrologie VFN, Praha ²
Published in the journal: Čes.-slov. Patol., 57, 2021, No. 2, p. 109-112
Category: Původní práce

Summary

Inflammatory bowel disease (IBD) is a group of chronic relapsing intestinal inflammatory processes primarily represented by ulcerative colitis (UC) and Crohn´s disease (CD). Nearly half of IBD cases are followed by extraintestinal complications and renal involvement can occur independatly or along with other complications and are described with the patients sufferring from UC or CD. Most frequent renal involvement is nephrolithiasis, tubulointerstinal nephritis, different kinds of glomerulonephritis and AA amyloidosis. We are presenting an unusal form of renal involvement of a young female patient with a severe form of Crohn´s disease treated with recombinant monoclonal antibodies.

Keywords:

Inflammatory bowel disease – Crohn´s disease – glomerulonephritis – kidney biopsy

Zdroje

Vavricka SR, Schoepfer A, Scharl M, et al. Extraintestinal Manifestations of Inflammatory Bowel Disease. Inflamm Bowel Dis 2015; 21(8): 1982–1992.
Ardizzone S, Puttini PS, Cassinotti A, et al. Extraintestinal manifestations of inflammatory bowel disease. Dig Liver Dis 2008; 40 (suppl 2): S253–S259.
Corica D et Romano C. Renal Involvement in Inflammatory Bowel Diseases. Journal of Crohn‘s and Colitis 2016; 226–235.
Braysh K, Gerges Geagea A, Matar C, et al. Kidney Manifestations of Inflammatory Bowel Diseases. Open Journal of Gastroenterology 2018; 8 : 172-191.
Vavricka SR, Brun L, Ballabeni P, et al. Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Am J Gastroenterol 2011; 106 : 110–119.
Filiopoulos V, Trompouki S, Hadjiyannakos D, et al. IgA nephropathy in association with Crohn’s disease: A case report and brief review of the literature. Ren Fail 2010; 32 : 523–527.
Takemura T, Okada M, Yagi K, et al. An adolescent with IgA nephropathy and Crohn disease: Pathogenetic implications. Pediatr Nephrol 2002; 17 : 863–866.
Fraser JS, Muller AF, Smith DJ, et al. Renal tubular injury is present in acute inflammatory bowel disease prior to introduce of drug therapy. Aliment Pharmacol Ther 2001; 15 : 1131-1137.
Pipili C, Michopoulos S, Sotiropoulou M, et al. Is there any association between IgA nephropathy, Crohn’s disease and Helicobacter pylori infection? Ren Fail 2012; 34 : 506–509.
Honsová E. Postinfekční glomerulonefritida u dospělých: skrytá tvář dlouho známého onemocnění. Cesk Patol 2016; 52(1): 61-64.
Wilcox GM, Aretz HT, Roy MA, et al. Glomerulonephritis Associated With Inflammatory Bowel Disease. Gastroenterology 1990; 98 : 788-791.
Kiryluk K, Li Y, Scolari F, et al. Discovery of New Risk Loci for IgA Nephropathy Implicates Genes Involved in Immunity against Intestinal Pathogens. Nature Genetics 2014; 46 : 1187-1196.
Choi JY, Yu CH, Jung HY, et al. A case of rapidly progressive IgA nephropathy in a patient with exacerbation of Crohn’s disease. BMC Nephrol 2012; 13 : 84.
Park S, Chun J, Han KD et al. Increased end-stage renal disease risk in patients with inflammatory bowel disease: A national population-based study. World J Gastroenterol 2018; 24 : 4798-4808.