Results of a pilot project: reconditioning training in patients with haematological malignancies

Česká verze

Authors: A. Janíková ¹; M. Hadrabová ¹; I. Hrnčiříková ²; P. Stejskal ²; Z. Svobodová ²; A. Malá ²; L. Dovrtělová ²; J. Šťastná ¹; K. Kapounková ²; J. Mayer ¹
Authors place of work: Interní hematologická a onkologická klinika FN Brno a Lékařské fakulty Masarykovy univerzity Brno ¹; Katedra podpory zdraví Fakulty sportovních studií Masarykovy univerzity Brno ²
Published in the journal: Transfuze Hematol. dnes,24, 2018, No. 1, p. 37-45.
Category: Původní práce

Summary

Premises:
The survival of patients suffering from haematological malignancies continues to improve. However, many patients in remission feel “ill” and in “poor shape” for a long time after successful treatment, a feeling triggered by decondition. The aim of our project was to verify in practice the feasibility, safety and efficacy of a structured training program.

Methods:
Patients were assessed at three time points: before starting oncological treatment, upon finishing it (in remis -⁠ sion) and after follow-up or after an interventional physical training program (IPP; duration of three months, frequency of 3 x weekly, duration of each session 60 minutes). The parameters studied included physical composition, aerobic capacity (maximum oxygen consumption %VO₂max/kg), sympathetic-vagal equilibrium (total score) and the muscular strength of the upper limbs (hand grip). These measurements also helped optimise the training load.

Results:
A total of 101 patients were assessed in the period from 2012 to 2016. Of these, 61 were only followed after treatment and 40 were included in the IPP (36/40 finished the IPP according to plan, 80% attendance). Significant deterioration of sympathetic-vagal equilibrium was noted during treatment (p = 0.04) as was a non-significant decrease in aerobic capacity (p = 0.18). In the IPP group, there was a significant increase in aerobic capacity (p = 0.001) as well as an improvement in sympathetic-vagal equilibrium (p = 0.02). In the group of patients who were only followed, we observed an increase in the body mass index (p = 0.01).

Conclusion:
These results demonstrate the good tolerance, feasibility and efficacy of IPP in patients in remission of their haemato-oncological disease. The disorder of sympathetic-vagal equilibrium appears to be crucial and may be effectively repaired using physical training.

Key words:
physical activity –⁠ lymphoma –⁠ leukaemia –⁠ supportive care

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