Zinc supplementation in premature infants: an overview of current recommendations and scientific findings

Česká verze

Authors: J. Dušek ^1,2
Authors place of work: Neonatologické oddělení Nemocnice České Budějovice, a. s. ¹; Zdravotně sociální fakulta Jihočeské univerzity v Českých Budějovicích ²
Published in the journal: Čes-slov Neonat 2025; 31 (2): 93-96.
Category: Původní práce

Summary

Zinc is a key trace element essential for growth, neurodevelopment, and immune function. Preterm infants are at risk of zinc deficiency due to insufficient intrauterine storage, increased postnatal needs, and higher losses. This article summarizes current recommendations for zinc supplementation in preterm infants, including ESPGHAN guidelines, and describes the role of zinc in growth, development, and immunity. It also discusses the risks of deficiency and over-supplementation, the relationship between zinc deficiency and neurodevelopmental disorders, and provides an overview of available clinical studies. Zinc supplementation is a key component of nutritional care in this vulnerable population.

Keywords:

supplementation – Immunity – Zinc – Neurodevelopment – growth – preterm infants – ESPGHAN

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