Authors: Daniel Driák Authors place of work: Gynekologicko-porodnická klinika, 1. lékařská fakulta Univerzity Karlovy v Praze a Nemocnice Na Bulovce Published in the journal: Čas. Lék. čes. 2012; 151: 459-462 Category: Přehledový článek
Incidence of sexually transmitted infections (diseases) has been already increasing again for more than one decade; the world number of 125-340 millions of new cases a year is estimated. Fifteen thousands of new HIV-positive persons daily present a substantial contribution to the total amount. Besides an increasing number of unplanned pregnancies, the huge spreading of sexually transmitted infections predominantly of the second generation is the main reason for a renewed interest in search of local contraceptives, i.e. spermicides. An urgent need for a new, non-detergent, synthetic or natural spermicide emerged to replace the traditional nonoxynol-9. New preparation of microbicidal spermicide should offer dual protection against both unplanned conception and sexually transmitted infections.
Key words: sexually transmitted infections, sexually transmitted diseases, spermicides, nonoxynol-9, non-detergent compound, antimicrobial peptides.
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