Ectopic pancreas as a cause of upper gastrointestinal bleeding

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Authors: Vacík M.; Shon F.; Řežábek M.
Authors place of work: Gastroenterologické oddělení, Nemocnice České Budějovice, a. s.
Published in the journal: Gastroent Hepatol 2019; 73(2): 132-137
Category: IBD: přehledová práce
doi: https://doi.org/10.14735/amgh2019132

Summary

Differentiated ectopic pancreatic tissue can develop anywhere in the gastrointestinal tract (GIT) and is most frequently found in the gastric or duodenal wall. Nowadays a development of ectopic pancreas stay unclear. The incidence of an ectopic pancreas is 0.55–13.70%, and such tissue is found more frequently in males than in females. Most ectopic pancreases are histologically categorized as type 1 according to Heinrich’s classification and contain all pancreatic components (acini, ducts, and endocrine cells). The majority of cases are asymptomatic; however, a large ectopic pancreas can cause various symptoms. Ectopic pancreatic tissue rarely causes bleeding. Here, we present two case reports. The first case was a middle-aged woman who developed anemia due to ectopic pancreatic tissue in the gastric wall. The second case exhibited acute bleeding due to a subpapillary lesion in the duodenum. Differential diagnosis can be difficult. Surgery and histological examination of the resected GIT led to a definitive diagnosis in both cases.

Conflict of Interest: Authors declare that the article/manuscript complies with ethical standards, patient anonymity has been respected, and states that they have no financial, advisory or other commercial interests in relation to the subject matter.

Publication Ethics: The article/manuscript has not been published or is currently being submitted to another review.

The authors agree to publish their name and e-mail in the published article/manuscript.

Dedication: Supported by Ministry of Health, Czech Republic –⁠ conceptual development of research organization 64165, General University Hospital in Prague, Czech Republic.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Keywords:

endoscopy – surgery – Pancreas – choristoma – ectopic tissue – bleeding – Gastrointestinal tract

Zdroje

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