Doporučení pro vyšetřování vrozených trombofilií v dětském věku

Guidelines for inherited thrombophilia testing in children

The incidence of thromboembolic disease in childhood is low compared to the adult population. Thrombophilia refers to factors that increase the risk of developing thrombosis. The most important factors in the development of thrombosis in children are acquired, with central venous catheters being the leading cause. In contrast, inherited thrombophilias play only a minor role. Approved consensus guidelines based on published literature specify the indications for testing for inherited thrombophilias and the scope of such testing. Incorrectly indicated, performed, and/or interpreted testing may be misleading and potentially harmful.

Keywords:

testing – thrombophilia – indication – childhood – thrombosis – inherited thrombophilia