Vývoj a využití jiných PET radiofarmak než FDG na Masarykově onkologickém ústavu

English version

Autoři: Ing. Jan Adam ^1,3; K. Bolcak ²; J. Kaderavek ³; F. Kuzel ³
Působiště autorů: Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic ¹; Department of Nuclear Medicine, Masaryk Memorial Cancer Institute, Brno, Czech Republic ²; Division of Radiopharmaceuticals, UJV Rez, a. s., Husinec-Rez, Czech Republic ³
Vyšlo v časopise: Klin Onkol 2012; 25(Supplementum 2): 82-86

Práce byla podpořena Evropským fondem pro regionální rozvoj a státním rozpočtem České republiky (OP VaVpI – RECAMO, CZ.1.05/2.1.00/03.0101).

Autoři deklarují, že v souvislosti s předmětem studie nemají žádné komerční zájmy.

Redakční rada potvrzuje, že rukopis práce splnil ICMJE kritéria pro publikace zasílané do bi omedicínských časopisů.

Obdrženo: 10. 10. 2012
Přijato: 31. 10. 2012

Souhrn

Existence cyklotronu a PET centra ÚJV Řež, a.s., v Masarykově onkologickém ústavu umožňuje výzkumníkům z RECAMO a Masarykova onkologického ústavu zapojit se do výzkumu, vývoje a využití nových radiofarmak včetně látek označených krátce žijícími pozitronovými zářiči (zejména [¹¹C]). V současnosti zde vstupuje do I. fáze klinického hodnocení [¹¹C]-značený tracer L-[methyl-¹¹C]methionin a na oddělení nukleární medicíny jsou prováděny skeny s jinými PET radiofarmaky než fluordeoxyglukózou. Spolupráce by měla pokračovat i nadále a v budoucnu vyústit ve zpřístupnění více možností pro PET zobrazování v České republice.

Klíčová slova:
pozitronová emisní tomografie –⁠ radiofarmaka –3‘-deoxy-3‘-[¹⁸F]fluorothymidin –⁠ [¹⁸F]fluorocholin –⁠ [¹⁸F]fluorid sodný –⁠ L-[methyl-¹¹C]methionin

Zdroje

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