Children obesity and its metabolic outcomes
Authors:
Zlatko Marinov 1; Dalibor Pastucha 2
Authors place of work:
FN Motol a 2. LF UK, Dětská poliklinika, Dětská obezitologická ambulance, Praha
1; Fakultní nemocnice Olomouc, Klinika tělovýchovného lékařství a kardiovaskulární rehabilitace
2
Published in the journal:
Čas. Lék. čes. 2012; 151: 135-140
Category:
Přehledové články
Summary
According to current statistics, there are, at an average child’s general practice about seventy children registered with obesity, including fifty children indicated for long-term treatment of obesity due to medical indications, fifteen children are intended for targeted modifications in their diet, and in almost every practice there is a child with a pathognomonic obesity. Currently, we are exposed to food-borne pandemic coupled polygenic obesity, which is a chronic metabolic disease with societal consequences. Alimentary obesity mainly reflects an early onset of cardio-metabolic risk, but the clinical picture of complications of childhood obesity is broader and includes not only the risk of life-limitation, but also respiratory, gastrointestinal, neurological, orthopaedic and endocrine complications along with serious psychosocial problems. The effects caused by childhood obesity are reversible initially, and early identification and treatment is a major clinical challenge in preventing the development of serious metabolic, organ, psychological and societal complications.
Key words:
obesity in children, cardio-metabolic risk, metabolic syndrome, liver steatosis, obstructive sleep apnea syndrome.
Zdroje
1. Vignerová J, Riedlová J, Bláha P, et al. 6. celostátní antropologický výzkum dětí a mládeže 2001. Česká republika. Souhrnné výsledky. PřF UK. Praha: SZÚ 2006; 238.
2. Marinov Z. Praktická dětská obezitologie. Praha: Grada Publishing 2012.
3. Ludwig DS. Childshood obesity – the shape of things to come. N Engl J Med 2007; 7(23): 2325–2327.
4. Lobstein T., Jackson-Leach R. Estimated burden of paediatric obesity and co-morbidities in Europe. Part 2. Numbers of children with indicators of obesity-related disease. Int J Pediatr Obes 2006; 1(1): 33–41.
5. Krásničanová H. Vztahy mezi tělesnou hmotností a skeltální a sexuální maturací. Stav výživy a biologický věk – vybrané auxologické aspekty. Postgraduální medicína 2010; 2(Suppl): 52–60.
6. Franks PW, Hanson RL, Knowler WC, et al. Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med. 2010; 362(6): 485–493.
7. Dam RM, Willett WC, Manson JE, Hu FB. The relationship between overweight in adolescence and premature death in women. Ann Intern Med 2006; 145(2): 91–97.
8. Avenell A, Broom J, Brown TJ, et al. Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement. Health Technol Assess 2004; 8(21): 1–182.
9. Christakis NA, Fowler JH. The spread of obesity in a large social network over 32 years. N Engl J Med 2007; 357(4): 370–379.
10. Hillier TA, Pedula KL, Schmidt MM, et al. Childhood obesity and metabolic imprinting. Diabetes Care 2007; 30(9): 2287–2292.
11. Franks PW, Ling C. Epigenetics and obesity: the devil is in the details. BMC Med 2010; 21(8): 88.
12. Ramachandrappa S, Farooqi IS. Genetic approaches to understanding human obesity. J Clin Invest 2011; 121(6): 2080–2086.
13. Dabelea D, Crume T. Maternal environment and the transgenerational cycle of obesity and diabetes. Diabetes 2011; 60(7): 1849–1855.
14. Pastucha D, Malinčíková J, Číhalík Č, et al. Obesity, hypertension and insulin resistance in childhood. Acta Medica Martinina. 2008; 8(1): 17–22.
15. Nobili V, Alisi A, Raponi M. Pediatric non-alcoholic fatty liver disease: preventive and therapeutic value of lifestyle intervention. World J Gastroenterol. 2009; 15(48): 6017–6022.
16. Kohler MJ, Thormaehlen S, Kennedy JD, et al. Differences in the association between obesity and obstructive sleep apnea among children and adolescents. J Clin Sleep Med 2009; 5(6): 506–511.
17. Horakova D, Stejskal D, Pastucha D, et al. Potential markers of insuline resistance in healthy vs obese and overweight subjects. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2010; 154(3): 245–250.
18. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003; 348(17): 1625–1638.
19. Reaven GM. The metabolic syndrome: is this diagnosis necessary? Am j Clin Nutr 2006; 83: 1237–1247.
20. Zimmet P, Alberti KG, Kaufman F, et al. The metabolic syndrome in children and adolescents - an IDF consensus report. Pediatr Diabetes 2007; 8(5): 299–306.
21. Simmons RK, Alberti KG, Gale EA, Colagiuri S, et al. The metabolic syndrome: useful concept or clinical tool? Diabetologia 2010; 53(4): 600–605.
22. Pastucha, D., Hyjánek, J., Horáková, D. Hypertenze dětského věku a její vztah k inzulinové rezistenci. Pediatrie pro praxi 2007; 8: 237–239.
23. Haffner SM, Miettinen H, Stern MP. The homeostasis model in the San Antonio heart study. Diabetes Care. 1997; 20: 1087–1092.
24. Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000; 85: 2402–2410.
25. Pastucha D, Talafa V, Malincikova J, et al. Obesity, hypertension and insulin resistance in Childhood – a pilot study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2010; 154(1): 77–82.
26. Steinberger J, Daniels SR, Eckel RH, et al. Progress and challenges in metabolic syndrome in children and adolescents. Circulation 2009; 119(4): 628–647.
27. Marinov Z, Čepová J. Metabolické parametry pacientů dětské obezitologické ambulance. Čs Pediatrie 2010; 2: 72–78.
28. Vitáriušová E, Košťálová Ľ, Pribilincová Z, et al. Výskyt metabolického syndrómu a jeho komponentov u obéznych detí. Čs Pediatrie 2010; 2: 55–61.
29. Ley RE. Obesity and the human microbiome. Curr Opin Gastroenterol 2010; 26: 5–11.
30. Musso G, Gambino R, Cassader M. Obesity, Diabetes, and Gut Microbiota. Diabetes Care 2010; 33: 2277–2284.
31. Nobili V, Alisi A, Raponi M. Pediatric non-alcoholic fatty liver disease: preventive and therapeutic value of lifestyle intervention. World J Gastroenterol 2009; 15(48): 6017–6022.
32. Chan DF, Li AM, Chu WC, et al. Hepatic steatosis in obese Chinese children. Int J Obes Rel et Metab Disord 2004; 28(10): 1257–1263.
33. Kohler MJ, Thormaehlen S, Kennedy JD, et al. Differences in the association between obesity and obstructive sleep apnea among children and adolescents. J Clin Sleep Med 2009; 5(6): 506–511.
34. Rodriguez MA, Winkleby MA, Ahn D, et al. Identification of population subgroups of children and adolescents with high asthma prevalence: findings from the Third National Health and Nutrition Examination Survey. Arch Pediatr Adolesc Med 2002; 156(3): 269–275.
35. Fontaine KR, Redden DT, Wang C, et al. Years of life lost due to obesity. JAMA 2003; 289(2): 187–193.
36. Marinov Z, Barčáková U, Nesrstová M, Pastucha D. S dětmi proti obezitě. Praha: IFP publishing 2011.
Štítky
Adiktologie Alergologie a imunologie Angiologie Audiologie a foniatrie Biochemie Dermatologie Dětská gastroenterologie Dětská chirurgie Dětská kardiologie Dětská neurologie Dětská otorinolaryngologie Dětská psychiatrie Dětská revmatologie Diabetologie Farmacie Chirurgie cévní Algeziologie Dentální hygienistkaČlánek vyšel v časopise
Časopis lékařů českých
- Orální lichen planus v kostce: Jak v praxi na toto multifaktoriální onemocnění s různorodými symptomy?
- Metamizol jako analgetikum první volby: kdy, pro koho, jak a proč?
- Intranazální fixní kombinace olopatadin hydrochlorid/momethason furoát v léčbě alergické rýmy
- Nejčastější nežádoucí účinky venlafaxinu během terapie odeznívají
Nejčtenější v tomto čísle
- Autofagie a její úloha v obranné a poškozující zánětové reakci*
- Běžná dětská obezita a její metabolické následky
- XV. celostátní konference DNA diagnostiky
- Zemřel prof. MUDr. Petr Zatloukal, CSc.