1. AmulicB, CazaletC, HayesGL, MetzlerKD, ZychlinskyA (2012) Neutrophil function: from mechanisms to disease. Annu Rev Immunol 30: 459–489.
2. MantovaniA, CassatellaMA, CostantiniC, JaillonS (2011) Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 11: 519–531.
3. ChtanovaT, SchaefferM, HanS-J, van DoorenGG, NollmannM, et al. (2008) Dynamics of Neutrophil Migration in Lymph Nodes during Infection. Immunity 29: 487–496.
4. BeauvillainC, CuninP, DoniA, ScotetM, JaillonS, et al. (2011) CCR7 is involved in the migration of neutrophils to lymph nodes. Blood 117: 1196–1204.
5. MullerI, MunderM, KropfP, HanschGM (2009) Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms? Trends Immunol 30: 522–530.
6. PillayJ, TakT, KampVM, KoendermanL (2013) Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: simil arities and differences. Cell Mol Life Sci
7. PillayJ, KampVM, van HoffenE, VisserT, TakT, et al. (2012) A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest 122: 327–336.
8. GabrilovichDI, NagarajS (2009) Myeloid-derived suppressor cells as regulators of the immune system. NatRevImmunol 9: 162–174.
9. RodriguezPC, ErnstoffMS, HernandezC, AtkinsM, ZabaletaJ, et al. (2009) Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer research 69: 1553–1560.
10. EruslanovE, NeubergerM, DaurkinI, PerrinGQ, AlgoodC, et al. (2012) Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer 130: 1109–1119.
11. HelZ, McGheeJR, MesteckyJ (2006) HIV infection: first battle decides the war. Trends Immunol 27: 274–281.
12. ReuterMA, PomboC, BettsMR (2012) Cytokine production and dysregulation in HIV pathogenesis: lessons for development of therapeutics and vaccines. Cytokine Growth Factor Rev 23: 181–191.
13. BettsMR, NasonMC, WestSM, De RosaSC, MiguelesSA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781–4789.
14. DayCL, KaufmannDE, KiepielaP, BrownJA, MoodleyES, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350–354.
15. BrenchleyJM, KarandikarNJ, BettsMR, AmbrozakDR, HillBJ, et al. (2003) Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood 101: 2711–2720.
16. El-FarM, HalwaniR, SaidE, TrautmannL, DoroudchiM, et al. (2008) T-cell exhaustion in HIV infection. Curr HIV/AIDS Rep 5: 13–19.
17. RosignoliG, CranageA, BurtonC, NelsonM, SteelA, et al. (2007) Expression of PD-L1, a marker of disease status, is not reduced by HAART in aviraemic patients. AIDS 21: 1379–1381.
18. FreemanGJ, LongAJ, IwaiY, BourqueK, ChernovaT, et al. (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 192: 1027–1034.
19. CarterL, FouserLA, JussifJ, FitzL, DengB, et al. (2002) PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol 32: 634–643.
20. KeirME, ButteMJ, FreemanGJ, SharpeAH (2008) PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 26: 677–704.
21. WherryEJ, HaSJ, KaechSM, HainingWN, SarkarS, et al. (2007) Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27: 670–684.
22. VeluV, TitanjiK, ZhuB, HusainS, PladevegaA, et al. (2009) Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458: 206–210.
23. Dyavar ShettyR, VeluV, TitanjiK, BosingerSE, FreemanGJ, et al. (2012) PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. J Clin Invest 122: 1712–1716.
24. FinnefrockAC, TangA, LiF, FreedDC, FengM, et al. (2009) PD-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination. J Immunol 182: 980–987.
25. MeierA, BagchiA, SidhuHK, AlterG, SuscovichTJ, et al. (2008) Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands. AIDS 22: 655–658.
26. Rodriguez-GarciaM, PorichisF, de JongOG, LeviK, DiefenbachTJ, et al. (2011) Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10. J Leukoc Biol 89: 507–515.
27. VollbrechtT, StirnerR, TufmanA, RoiderJ, HuberRM, et al. (2012) Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells. AIDS 26: F31–37.
28. ClokeT, MunderM, BerginP, HerathS, ModolellM, et al. (2013) Phenotypic Alteration of Neutrophils in the Blood of HIV Seropositive Patients. PLoS One 8: e72034.
29. BoassoA, HardyAW, LandayAL, MartinsonJL, AndersonSA, et al. (2008) PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes. Clin Immunol 129: 132–144.
30. BrenchleyJM, DouekDC (2012) Microbial translocation across the GI tract. Annu Rev Immunol 30: 149–173.
31. SandlerNG, WandH, RoqueA, LawM, NasonMC, et al. (2011) Plasma levels of soluble CD14 independently predict mortality in HIV infection. The Journal of infectious diseases 203: 780–790.
32. SandlerNG, KohC, RoqueA, EcclestonJL, SiegelRB, et al. (2011) Host Response to Translocated Microbial Products Predicts Outcomes of Patients with HBV or HCV infection. Gastroenterology 141: 1220–30.
33. BrenchleyJM, PriceDA, SchackerTW, AsherTE, SilvestriG, et al. (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. NatMed 12: 1365–1371.
34. WorthenGS, AvdiN, VukajlovichS, TobiasPS (1992) Neutrophil adherence induced by lipopolysaccharide in vitro. Role of plasma component interaction with lipopolysaccharide. J Clin Invest 90: 2526–2535.
35. PapagnoL, SpinaCA, MarchantA, SalioM, RuferN, et al. (2004) Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoSBiol 2: E20.
36. GoicoecheaM, SmithDM, LiuL, MayS, TenorioAR, et al. (2006) Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J InfectDis 194: 29–37.
37. ClokeTE, GarveyL, ChoiBS, AbebeT, HailuA, et al. (2010) Increased level of arginase activity correlates with disease severity in HIV-seropositive patients. J Infect Dis 202: 374–385.
38. MunderM (2009) Arginase: an emerging key player in the mammalian immune system. BrJPharmacol 158: 638–651.
39. ThewissenM, DamoiseauxJ, van de GaarJ, TervaertJWC (2011) Neutrophils and T cells: Bidirectional effects and functional interferences. Molecular Immunology 48: 2094–2101.
40. YamamotoS, NavaRG, ZhuJ, HuangHJ, IbrahimM, et al. (2012) Cutting edge: Pseudomonas aeruginosa abolishes established lung transplant tolerance by stimulating B7 expression on neutrophils. J Immunol 189: 4221–4225.
41. de KleijnS, LangereisJD, LeentjensJ, KoxM, NeteaMG, et al. (2013) IFN-gamma-Stimulated Neutrophils Suppress Lymphocyte Proliferation through Expression of PD-L1. PLoS One 8: e72249.
42. HotchkissRS, CoopersmithCM, McDunnJE, FergusonTA (2009) The sepsis seesaw: tilting toward immunosuppression. Nat Med 15: 496–497.
43. TateMD, DengYM, JonesJE, AndersonGP, BrooksAG, et al. (2009) Neutrophils ameliorate lung injury and the development of severe disease during influenza infection. J Immunol 183: 7441–7450.
44. FujisawaH (2008) Neutrophils play an essential role in cooperation with antibody in both protection against and recovery from pulmonary infection with influenza virus in mice. J Virol 82: 2772–2783.
45. McNabFW, BerryMP, GrahamCM, BlochSA, OniT, et al. (2011) Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis. Eur J Immunol 41: 1941–1947.
46. ClokeT, MunderM, TaylorG, MullerI, KropfP (2012) Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection. PLoS One 7: e48939.
47. RodriguezPC, QuicenoDG, OchoaAC (2007) L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood 109: 1568–1573.
48. BuckleyCD, RossEA, McGettrickHM, OsborneCE, HaworthO, et al. (2006) Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration. J Leukoc Biol 79: 303–311.
49. KaplanMJ, RadicM (2012) Neutrophil extracellular traps: double-edged swords of innate immunity. J Immunol 189: 2689–2695.
50. KropfP, BaudD, MarshallSE, MunderM, MosleyA, et al. (2007) Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy. Eur J Immunol 37: 935–945.
51. PrinceLR, WhyteMK, SabroeI, ParkerLC (2011) The role of TLRs in neutrophil activation. Curr Opin Pharmacol 11: 397–403.
52. HerbeuvalJP, NilssonJ, BoassoA, HardyAW, KruhlakMJ, et al. (2006) Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients. Proc Natl Acad Sci U S A 103: 7000–7005.
53. von SydowM, SonnerborgA, GainesH, StrannegardO (1991) Interferon-alpha and tumor necrosis factor-alpha in serum of patients in various stages of HIV-1 infection. AIDS Res Hum Retroviruses 7: 375–380.
54. ShadduckPP, WeinbergJB, HaneyAF, BartlettJA, LangloisAJ, et al. (1991) Lack of enhancing effect of human anti-human immunodeficiency virus type 1 (HIV-1) antibody on HIV-1 infection of human blood monocytes and peritoneal macrophages. J Virol 65: 4309–4316.