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ReklamaPLOS Genetics - Číslo 5/2020
Research Article
1008185A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK BiobankBeate Leppert, Louise A. C. Millard, Lucy Riglin, George Davey Smith, Anita Thapar, Kate Tilling, Esther Walton, Evie Stergiakouli
1008255Depletion of Ric-8B leads to reduced mTORC2 activityMaíra H. Nagai, Victor P. S. Xavier, Luciana M. Gutiyama, Cleiton F. Machado, Alice H. Reis, Elisa R. Donnard, Pedro A. F. Galante, Jose G. Abreu, William T. Festuccia, Bettina Malnic
1008274A copy number variant is associated with a spectrum of pigmentation patterns in the rock pigeon (Columba livia)Rebecca Bruders, Hannah Van Hollebeke, Edward J. Osborne, Zev Kronenberg, Emily Maclary, Mark Yandell, Michael D. Shapiro
1008361An osteocalcin-deficient mouse strain without endocrine abnormalitiesCassandra R. Diegel, Steven Hann, Ugur M. Ayturk, Jennifer C. W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, VAI Vivarium and Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexander G. Robling, Matthew L. Warman, Bart O. Williams
1008586Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle massTakeshi Moriishi, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Tomoka Hasegawa, Toshihiro Miyazaki, Wenguang Liu, Ryo Fukuyama, Yuying Wang, Hisato Komori, Xin Qin, Norio Amizuka, Toshihisa Komori
1008612Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture modelDominic Holland, Oleksandr Frei, Rahul Desikan, Chun-Chieh Fan, Alexey A. Shadrin, Olav B. Smeland, V. S. Sundar, Paul Thompson, Ole A. Andreassen, Anders M. Dale
1008619Accounting for long-range correlations in genome-wide simulations of large cohortsDominic Nelson, Jerome Kelleher, Aaron P. Ragsdale, Claudia Moreau, Gil McVean, Simon Gravel
1008639Novel frameshift variant in MYL2 reveals molecular differences between dominant and recessive forms of hypertrophic cardiomyopathySathiya N. Manivannan, Sihem Darouich, Aida Masmoudi, David Gordon, Gloria Zender, Zhe Han, Sara Fitzgerald-Butt, Peter White, Kim L. McBride, Maher Kharrat, Vidu Garg
1008681The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2)Christos N. Velanis, Pumi Perera, Bennett Thomson, Erica de Leau, Shih Chieh Liang, Ben Hartwig, Alex Förderer, Harry Thornton, Pedro Arede, Jiawen Chen, Kimberly M. Webb, Serin Gümüs, Geert De Jaeger, Clinton A. Page, C. Nathan Hancock, Christos Spanos, Juri Rappsilber, Philipp Voigt, Franziska Turck, Frank Wellmer, Justin Goodrich, Alexander Förderer
1008682Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucomaYosuke Tanigawa, Michael Wainberg, Juha Karjalainen, Tuomo Kiiskinen, Guhan Venkataraman, Susanna Lemmelä, Joni A. Turunen, Robert R. Graham, Aki S. Havulinna, Markus Perola, Aarno Palotie, , Mark J. Daly, Manuel A. Rivas
1008722The phosphorelay BarA/SirA activates the non-cognate regulator RcsB in Salmonella entericaHubert Salvail, Eduardo A. Groisman
1008742Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta)Marina Brasó-Vives, Inna S. Povolotskaya, Diego A. Hartasánchez, Xavier Farré, Marcos Fernandez-Callejo, Muthuswamy Raveendran, R. Alan Harris, Douglas L. Rosene, Belen Lorente-Galdos, Arcadi Navarro, Tomas Marques-Bonet, Jeffrey Rogers, David Juan, Inna S. Povolotskaya, Marcos Fernandez-Callejo, Muthuswamy Raveendran, R. Alan Harris, Douglas L. Rosene, Belen Lorente-Galdos, Jeffrey Rogers
1008743The genomic landscape of metastasis in treatment-naïve breast cancer modelsChristina Ross, Karol Szczepanek, Maxwell Lee, Howard Yang, Tinghu Qiu, Jack Sanford, Kent Hunter, Jack D. Sanford
1008747Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancyFasil Tekola-Ayele, Cuilin Zhang, Jing Wu, Katherine L. Grantz, Mohammad L. Rahman, Deepika Shrestha, Marion Ouidir, Tsegaselassie Workalemahu, Michael Y. Tsai
1008749Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelagoHeini M. Natri, Katalina S. Bobowik, Pradiptajati Kusuma, Chelzie Crenna Darusallam, Guy S. Jacobs, Georgi Hudjashov, J. Stephen Lansing, Herawati Sudoyo, Nicholas E. Banovich, Murray P. Cox, Irene Gallego Romero
1008754Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nucleiShan Jiang, Katherine Williams, Xiangduo Kong, Weihua Zeng, Nam Viet Nguyen, Xinyi Ma, Rabi Tawil, Kyoko Yokomori, Ali Mortazavi
1008755Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongationSarina Y. Porcella, Natasha C. Koussa, Colin P. Tang, Daphne N. Kramer, Priyanka Srivastava, Duncan J. Smith
1008757Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvaeDavide Marchi, Kirankumar Santhakumar, Eleanor Markham, Nan Li, Karl-Heinz Storbeck, Nils Krone, Vincent T. Cunliffe, Fredericus J. M. van Eeden
1008763An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recyclingJinghu Gao, Linyue Zhao, Qian Luo, Shuyao Liu, Ziyang Lin, Peixiang Wang, Xin Fu, Juan Chen, Hongjie Zhang, Long Lin, Anbing Shi
1008766Simultaneous SNP selection and adjustment for population structure in high dimensional prediction modelsSahir R. Bhatnagar, Yi Yang, Tianyuan Lu, Erwin Schurr, JC Loredo-Osti, Marie Forest, Karim Oualkacha, Celia M. T. Greenwood
1008767Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobeHuey Hing, Noah Reger, Jennifer Snyder, Lee G. Fradkin
1008768Additive and mostly adaptive plastic responses of gene expression to multiple stress in Tribolium castaneumEva L. Koch, Frédéric Guillaume
1008769Polyploidy breaks speciation barriers in Australian burrowing frogs NeobatrachusPolina Yu. Novikova, Ian G. Brennan, William Booker, Michael Mahony, Paul Doughty, Alan R. Lemmon, Emily Moriarty Lemmon, J. Dale Roberts, Levi Yant, Yves Van de Peer, J. Scott Keogh, Stephen C. Donnellan
1008770Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormoneStine M. Præstholm, Majken S. Siersbæk, Ronni Nielsen, Xuguang Zhu, Anthony Hollenberg, Sheue-yann Cheng, Lars Grøntved, Anthony N. Hollenberg
1008772A new neuropeptide insect parathyroid hormone iPTH in the red flour beetle Tribolium castaneumJia Xie, Ming Sang, Xiaowen Song, Sisi Zhang, Donghun Kim, Jan A. Veenstra, Yoonseong Park, Bin Li
1008773Scalable probabilistic PCA for large-scale genetic variation dataAman Agrawal, Alec M. Chiu, Minh Le, Eran Halperin, Sriram Sankararaman, Eran Halperin, Sriram Sankararaman
1008777An Out-of-Patagonia migration explains the worldwide diversity and distribution of Saccharomyces eubayanus lineagesRoberto F. Nespolo, Carlos A. Villarroel, Christian I. Oporto, Sebastián M. Tapia, Franco Vega-Macaya, Kamila Urbina, Matteo De Chiara, Simone Mozzachiodi, Ekaterina Mikhalev, Dawn Thompson, Luis F. Larrondo, Pablo Saenz-Agudelo, Gianni Liti, Francisco A. Cubillos
1008782Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expressionAdrian Santos-Ledo, Sam Washer, Tamil Dhanaseelan, Lorraine Eley, Ahlam Alqatani, Paul W. Chrystal, Tania Papoutsi, Deborah J. Henderson, Bill Chaudhry
1008786ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencingJiaxin Fan, Jian Hu, Chenyi Xue, Hanrui Zhang, Katalin Susztak, Muredach P. Reilly, Rui Xiao, Mingyao Li
1008787ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resectionFernando Mejías-Navarro, Guillermo Rodríguez-Real, Javier Ramón, Rosa Camarillo, Pablo Huertas
1008789A high-fat diet induces a microbiota-dependent increase in stem cell activity in the Drosophila intestineJakob von Frieling, Muhammed Naeem Faisal, Femke Sporn, Roxana Pfefferkorn, Stella Solveig Nolte, Felix Sommer, Philip Rosenstiel, Thomas Roeder
1008791The genetic architecture of the maize progenitor, teosinte, and how it was altered during maize domesticationQiuyue Chen, Luis Fernando Samayoa, Chin Jian Yang, Peter J. Bradbury, Bode A. Olukolu, Michael A. Neumeyer, Maria Cinta Romay, Qi Sun, Anne Lorant, Edward S. Buckler, Jeffrey Ross-Ibarra, James B. Holland, John F. Doebley
1008794Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegyptiLaura B. Dickson, Sarah H. Merkling, Mathieu Gautier, Amine Ghozlane, Davy Jiolle, Christophe Paupy, Diego Ayala, Isabelle Moltini-Conclois, Albin Fontaine, Louis Lambrechts
1008796Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2Dana Lau-Corona, Woo Kyun Bae, Lothar Hennighausen, David J. Waxman
1008797UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in ArabidopsisEleni Tavridou, Emanuel Schmid-Siegert, Christian Fankhauser, Roman Ulm
1008798Yeast mismatch repair components are required for stable inheritance of gene silencingQian Liu, Xuefeng Zhu, Michelle Lindström, Yonghong Shi, Ju Zheng, Xinxin Hao, Claes M. Gustafsson, Beidong Liu
10088011008804Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertilityMaya Hiltpold, Guanglin Niu, Naveen Kumar Kadri, Danang Crysnanto, Zih-Hua Fang, Mirjam Spengeler, Fritz Schmitz-Hsu, Christian Fuerst, Hermann Schwarzenbacher, Franz R. Seefried, Frauke Seehusen, Ulrich Witschi, Angelika Schnieke, Ruedi Fries, Heinrich Bollwein, Krzysztof Flisikowski, Hubert Pausch
1008807The temporal regulation of TEK contributes to pollen wall exine patterningShuang-Xi Xiong, Qiu-Ye Zeng, Jian-Qiao Hou, Ling-Li Hou, Jun Zhu, Min Yang, Zhong-Nan Yang, Yue Lou
1008815Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye developmentPaolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Veronica Lisi, Valeria Palumbo, Simone D'Angeli, Stefano Cacchione, Giovanni Cenci, Laura Ciapponi, James G. Wakefield, Maurizio Gatti, Grazia Daniela Raffa
1008816Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cellsErin K. Schwartz, Shih-Hsun Hung, Damon Meyer, Aurèle Piazza, Kevin Yan, Becky Xu Hua Fu, Wolf-Dietrich Heyer
1008818Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytesMarco Gründl, Susanne Walz, Laura Hauf, Melissa Schwab, Kerstin Marcela Werner, Susanne Spahr, Clemens Schulte, Hans Michael Maric, Carsten P. Ade, Stefan Gaubatz
1008823Glucose transporter 10 modulates adipogenesis via an ascorbic acid-mediated pathway to protect mice against diet-induced metabolic dysregulationChung-Lin Jiang, Wei-Ping Jen, Chang-Yu Tsao, Li-Ching Chang, Chien-Hsiun Chen, Yi-Ching Lee
1008826Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophyShigefumi Morioka, Hirofumi Sakaguchi, Hiroaki Mohri, Mariko Taniguchi-Ikeda, Motoi Kanagawa, Toshiaki Suzuki, Yuko Miyagoe-Suzuki, Tatsushi Toda, Naoaki Saito, Takehiko Ueyama
1008827Population genetic models of GERP scores suggest pervasive turnover of constrained sites across mammalian evolutionChristian D. Huber, Bernard Y. Kim, Kirk E. Lohmueller
1008832The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcriptionXiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H. Yu, Muriel Boube, Henri-Marc G. Bourbon, Jian-Quan Ni, Jun-Yuan Ji
Correction
1008795Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial InfectionErsheng Kuang, Cheryl Y. M. Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R. Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C. Reed, Limor Broday, Victor Nizet, Ze'ev A. Ronai
1008845Correction: The persimmon genome reveals clues to the evolution of a lineage-specific sex determination system in plantsTakashi Akagi, Kenta Shirasawa, Hideki Nagasaki, Hideki Hirakawa, Ryutaro Tao, Luca Comai, Isabelle M. Henry
1008854Correction: Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosomeJason Talkish, Haller Igel, Rhonda J. Perriman, Lily Shiue, Sol Katzman, Elizabeth M. Munding, Robert Shelansky, John Paul Donohue, Manuel Ares Jr.
PLOS Genetics
2020 Číslo 5
Nejčtenější v tomto čísle- A new neuropeptide insect parathyroid hormone iPTH in the red flour beetle Tribolium castaneum
- The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2)
- Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus
- The phosphorelay BarA/SirA activates the non-cognate regulator RcsB in Salmonella enterica
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