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PLOS Genetics - Číslo 5/2020

Correction

1008795
Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection

Ersheng Kuang, Cheryl Y. M. Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R. Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C. Reed, Limor Broday, Victor Nizet, Ze'ev A. Ronai

1008845
Correction: The persimmon genome reveals clues to the evolution of a lineage-specific sex determination system in plants

Takashi Akagi, Kenta Shirasawa, Hideki Nagasaki, Hideki Hirakawa, Ryutaro Tao, Luca Comai, Isabelle M. Henry

1008854
Correction: Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

Jason Talkish, Haller Igel, Rhonda J. Perriman, Lily Shiue, Sol Katzman, Elizabeth M. Munding, Robert Shelansky, John Paul Donohue, Manuel Ares Jr.


Research Article

1008185
A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank

Beate Leppert, Louise A. C. Millard, Lucy Riglin, George Davey Smith, Anita Thapar, Kate Tilling, Esther Walton, Evie Stergiakouli

1008255
Depletion of Ric-8B leads to reduced mTORC2 activity

Maíra H. Nagai, Victor P. S. Xavier, Luciana M. Gutiyama, Cleiton F. Machado, Alice H. Reis, Elisa R. Donnard, Pedro A. F. Galante, Jose G. Abreu, William T. Festuccia, Bettina Malnic

1008274
A copy number variant is associated with a spectrum of pigmentation patterns in the rock pigeon (Columba livia)

Rebecca Bruders, Hannah Van Hollebeke, Edward J. Osborne, Zev Kronenberg, Emily Maclary, Mark Yandell, Michael D. Shapiro

1008361
An osteocalcin-deficient mouse strain without endocrine abnormalities

Cassandra R. Diegel, Steven Hann, Ugur M. Ayturk, Jennifer C. W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, VAI Vivarium and Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexander G. Robling, Matthew L. Warman, Bart O. Williams

1008586
Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass

Takeshi Moriishi, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Tomoka Hasegawa, Toshihiro Miyazaki, Wenguang Liu, Ryo Fukuyama, Yuying Wang, Hisato Komori, Xin Qin, Norio Amizuka, Toshihisa Komori

1008612
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model

Dominic Holland, Oleksandr Frei, Rahul Desikan, Chun-Chieh Fan, Alexey A. Shadrin, Olav B. Smeland, V. S. Sundar, Paul Thompson, Ole A. Andreassen, Anders M. Dale

1008619
Accounting for long-range correlations in genome-wide simulations of large cohorts

Dominic Nelson, Jerome Kelleher, Aaron P. Ragsdale, Claudia Moreau, Gil McVean, Simon Gravel

1008639
Novel frameshift variant in MYL2 reveals molecular differences between dominant and recessive forms of hypertrophic cardiomyopathy

Sathiya N. Manivannan, Sihem Darouich, Aida Masmoudi, David Gordon, Gloria Zender, Zhe Han, Sara Fitzgerald-Butt, Peter White, Kim L. McBride, Maher Kharrat, Vidu Garg

1008681
The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2)

Christos N. Velanis, Pumi Perera, Bennett Thomson, Erica de Leau, Shih Chieh Liang, Ben Hartwig, Alex Förderer, Harry Thornton, Pedro Arede, Jiawen Chen, Kimberly M. Webb, Serin Gümüs, Geert De Jaeger, Clinton A. Page, C. Nathan Hancock, Christos Spanos, Juri Rappsilber, Philipp Voigt, Franziska Turck, Frank Wellmer, Justin Goodrich, Alexander Förderer

1008682
Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

Yosuke Tanigawa, Michael Wainberg, Juha Karjalainen, Tuomo Kiiskinen, Guhan Venkataraman, Susanna Lemmelä, Joni A. Turunen, Robert R. Graham, Aki S. Havulinna, Markus Perola, Aarno Palotie, , Mark J. Daly, Manuel A. Rivas

1008722
The phosphorelay BarA/SirA activates the non-cognate regulator RcsB in Salmonella enterica

Hubert Salvail, Eduardo A. Groisman

1008742
Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta)

Marina Brasó-Vives, Inna S. Povolotskaya, Diego A. Hartasánchez, Xavier Farré, Marcos Fernandez-Callejo, Muthuswamy Raveendran, R. Alan Harris, Douglas L. Rosene, Belen Lorente-Galdos, Arcadi Navarro, Tomas Marques-Bonet, Jeffrey Rogers, David Juan, Inna S. Povolotskaya, Marcos Fernandez-Callejo, Muthuswamy Raveendran, R. Alan Harris, Douglas L. Rosene, Belen Lorente-Galdos, Jeffrey Rogers

1008743
The genomic landscape of metastasis in treatment-naïve breast cancer models

Christina Ross, Karol Szczepanek, Maxwell Lee, Howard Yang, Tinghu Qiu, Jack Sanford, Kent Hunter, Jack D. Sanford

1008747
Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy

Fasil Tekola-Ayele, Cuilin Zhang, Jing Wu, Katherine L. Grantz, Mohammad L. Rahman, Deepika Shrestha, Marion Ouidir, Tsegaselassie Workalemahu, Michael Y. Tsai

1008749
Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago

Heini M. Natri, Katalina S. Bobowik, Pradiptajati Kusuma, Chelzie Crenna Darusallam, Guy S. Jacobs, Georgi Hudjashov, J. Stephen Lansing, Herawati Sudoyo, Nicholas E. Banovich, Murray P. Cox, Irene Gallego Romero

1008754
Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei

Shan Jiang, Katherine Williams, Xiangduo Kong, Weihua Zeng, Nam Viet Nguyen, Xinyi Ma, Rabi Tawil, Kyoko Yokomori, Ali Mortazavi

1008755
Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation

Sarina Y. Porcella, Natasha C. Koussa, Colin P. Tang, Daphne N. Kramer, Priyanka Srivastava, Duncan J. Smith

1008757
Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae

Davide Marchi, Kirankumar Santhakumar, Eleanor Markham, Nan Li, Karl-Heinz Storbeck, Nils Krone, Vincent T. Cunliffe, Fredericus J. M. van Eeden

1008763
An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recycling

Jinghu Gao, Linyue Zhao, Qian Luo, Shuyao Liu, Ziyang Lin, Peixiang Wang, Xin Fu, Juan Chen, Hongjie Zhang, Long Lin, Anbing Shi

1008766
Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

Sahir R. Bhatnagar, Yi Yang, Tianyuan Lu, Erwin Schurr, JC Loredo-Osti, Marie Forest, Karim Oualkacha, Celia M. T. Greenwood

1008767
Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobe

Huey Hing, Noah Reger, Jennifer Snyder, Lee G. Fradkin

1008768
Additive and mostly adaptive plastic responses of gene expression to multiple stress in Tribolium castaneum

Eva L. Koch, Frédéric Guillaume

1008769
Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus

Polina Yu. Novikova, Ian G. Brennan, William Booker, Michael Mahony, Paul Doughty, Alan R. Lemmon, Emily Moriarty Lemmon, J. Dale Roberts, Levi Yant, Yves Van de Peer, J. Scott Keogh, Stephen C. Donnellan

1008770
Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone

Stine M. Præstholm, Majken S. Siersbæk, Ronni Nielsen, Xuguang Zhu, Anthony Hollenberg, Sheue-yann Cheng, Lars Grøntved, Anthony N. Hollenberg

1008772
A new neuropeptide insect parathyroid hormone iPTH in the red flour beetle Tribolium castaneum

Jia Xie, Ming Sang, Xiaowen Song, Sisi Zhang, Donghun Kim, Jan A. Veenstra, Yoonseong Park, Bin Li

1008773
Scalable probabilistic PCA for large-scale genetic variation data

Aman Agrawal, Alec M. Chiu, Minh Le, Eran Halperin, Sriram Sankararaman, Eran Halperin, Sriram Sankararaman

1008777
An Out-of-Patagonia migration explains the worldwide diversity and distribution of Saccharomyces eubayanus lineages

Roberto F. Nespolo, Carlos A. Villarroel, Christian I. Oporto, Sebastián M. Tapia, Franco Vega-Macaya, Kamila Urbina, Matteo De Chiara, Simone Mozzachiodi, Ekaterina Mikhalev, Dawn Thompson, Luis F. Larrondo, Pablo Saenz-Agudelo, Gianni Liti, Francisco A. Cubillos

1008782
Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression

Adrian Santos-Ledo, Sam Washer, Tamil Dhanaseelan, Lorraine Eley, Ahlam Alqatani, Paul W. Chrystal, Tania Papoutsi, Deborah J. Henderson, Bill Chaudhry

1008786
ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing

Jiaxin Fan, Jian Hu, Chenyi Xue, Hanrui Zhang, Katalin Susztak, Muredach P. Reilly, Rui Xiao, Mingyao Li

1008787
ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection

Fernando Mejías-Navarro, Guillermo Rodríguez-Real, Javier Ramón, Rosa Camarillo, Pablo Huertas

1008789
A high-fat diet induces a microbiota-dependent increase in stem cell activity in the Drosophila intestine

Jakob von Frieling, Muhammed Naeem Faisal, Femke Sporn, Roxana Pfefferkorn, Stella Solveig Nolte, Felix Sommer, Philip Rosenstiel, Thomas Roeder

1008791
The genetic architecture of the maize progenitor, teosinte, and how it was altered during maize domestication

Qiuyue Chen, Luis Fernando Samayoa, Chin Jian Yang, Peter J. Bradbury, Bode A. Olukolu, Michael A. Neumeyer, Maria Cinta Romay, Qi Sun, Anne Lorant, Edward S. Buckler, Jeffrey Ross-Ibarra, James B. Holland, John F. Doebley

1008794
Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegypti

Laura B. Dickson, Sarah H. Merkling, Mathieu Gautier, Amine Ghozlane, Davy Jiolle, Christophe Paupy, Diego Ayala, Isabelle Moltini-Conclois, Albin Fontaine, Louis Lambrechts

1008796
Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2

Dana Lau-Corona, Woo Kyun Bae, Lothar Hennighausen, David J. Waxman

1008797
UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in Arabidopsis

Eleni Tavridou, Emanuel Schmid-Siegert, Christian Fankhauser, Roman Ulm

1008798
Yeast mismatch repair components are required for stable inheritance of gene silencing

Qian Liu, Xuefeng Zhu, Michelle Lindström, Yonghong Shi, Ju Zheng, Xinxin Hao, Claes M. Gustafsson, Beidong Liu

1008801
Dynamic genetic architecture of yeast response to environmental perturbation shed light on origin of cryptic genetic variation

Yanjun Zan, Örjan Carlborg

1008804
Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

Maya Hiltpold, Guanglin Niu, Naveen Kumar Kadri, Danang Crysnanto, Zih-Hua Fang, Mirjam Spengeler, Fritz Schmitz-Hsu, Christian Fuerst, Hermann Schwarzenbacher, Franz R. Seefried, Frauke Seehusen, Ulrich Witschi, Angelika Schnieke, Ruedi Fries, Heinrich Bollwein, Krzysztof Flisikowski, Hubert Pausch

1008807
The temporal regulation of TEK contributes to pollen wall exine patterning

Shuang-Xi Xiong, Qiu-Ye Zeng, Jian-Qiao Hou, Ling-Li Hou, Jun Zhu, Min Yang, Zhong-Nan Yang, Yue Lou

1008815
Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Paolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Veronica Lisi, Valeria Palumbo, Simone D'Angeli, Stefano Cacchione, Giovanni Cenci, Laura Ciapponi, James G. Wakefield, Maurizio Gatti, Grazia Daniela Raffa

1008816
Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells

Erin K. Schwartz, Shih-Hsun Hung, Damon Meyer, Aurèle Piazza, Kevin Yan, Becky Xu Hua Fu, Wolf-Dietrich Heyer

1008818
Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

Marco Gründl, Susanne Walz, Laura Hauf, Melissa Schwab, Kerstin Marcela Werner, Susanne Spahr, Clemens Schulte, Hans Michael Maric, Carsten P. Ade, Stefan Gaubatz

1008823
Glucose transporter 10 modulates adipogenesis via an ascorbic acid-mediated pathway to protect mice against diet-induced metabolic dysregulation

Chung-Lin Jiang, Wei-Ping Jen, Chang-Yu Tsao, Li-Ching Chang, Chien-Hsiun Chen, Yi-Ching Lee

1008826
Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy

Shigefumi Morioka, Hirofumi Sakaguchi, Hiroaki Mohri, Mariko Taniguchi-Ikeda, Motoi Kanagawa, Toshiaki Suzuki, Yuko Miyagoe-Suzuki, Tatsushi Toda, Naoaki Saito, Takehiko Ueyama

1008827
Population genetic models of GERP scores suggest pervasive turnover of constrained sites across mammalian evolution

Christian D. Huber, Bernard Y. Kim, Kirk E. Lohmueller

1008832
The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription

Xiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H. Yu, Muriel Boube, Henri-Marc G. Bourbon, Jian-Quan Ni, Jun-Yuan Ji


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