How to assess high-sensitive troponin T in newborns?

Česká verze

Authors: P. Jehlička ¹; M. Matas ²; D. Rajdl ³; M. Huml ¹; A. Mocková ²; J. Dort ²; P. Brož ³; J. Sýkora ¹
Authors place of work: Dětská klinika, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni přednosta prof. MUDr. J. Sýkora, Ph. D. ¹; Neonatologické oddělení, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni primář doc. MUDr. J. Dort, Ph. D. ²; Ústav klinické hematologie a biochemie, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni přednosta prof. MUDr. J. Racek, DrSc. ³
Published in the journal: Čes-slov Pediat 2016; 71 (4): 212-215.
Category: Původní práce

Summary

In the prospective study cord blood samples were tested for high-sensitivity troponin T reference concentration in 454 healthy full termed newborns. The hscTnT levels in healthy newborns were significantly higher than levels in adult population (median [IQR] 38.2 [31.3–48.0] ng/l, reference interval: 20.1–83.0 ng/l). We found statistically higher hscTnT in boys when compared to girls (p=0.05). Concentrations of hscTnT were lower in newborns who underwent cesarean section than delivered vaginally (p=0.008). Furthermore, hscTnT was statistically significantly decreased in hemolytic blood samples (hemolysis level >2 g/l, p<0.05). Identified reference values of hscTnT based on this study may contribute to more precise assessment of newborns with suspicion of a myocardial disorder.

Key words:
high-sensitivity troponin T, newborns, myocardial disorder, hemolysis

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