PLOS Genetics - Číslo 9/2014

Review

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Trans-kingdom Cross-Talk: Small RNAs on the Move
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Out of Balance: R-loops in Human Disease

Perspective

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Translational Regulation of the Post-Translational Circadian Mechanism

Research Article

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An Evolutionarily Conserved Role for the Aryl Hydrocarbon Receptor in the Regulation of Movement
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BMPs Regulate Gene Expression in the Dorsal Neuroectoderm of and Vertebrates by Distinct Mechanisms
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Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation
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Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development
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Meta-analysis of Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments
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The Proprotein Convertase KPC-1/Furin Controls Branching and Self-avoidance of Sensory Dendrites in
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Hydroxymethylated Cytosines Are Associated with Elevated C to G Transversion Rates
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Memory and Fitness Optimization of Bacteria under Fluctuating Environments
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Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence
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Interspecific Tests of Allelism Reveal the Evolutionary Timing and Pattern of Accumulation of Reproductive Isolation Mutations
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PRO40 Is a Scaffold Protein of the Cell Wall Integrity Pathway, Linking the MAP Kinase Module to the Upstream Activator Protein Kinase C
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Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Endocycling Cells
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SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene
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RRP6L1 and RRP6L2 Function in Silencing Regulation of Antisense RNA Synthesis
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Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control
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Positive Selection and Multiple Losses of the LINE-1-Derived Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency
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Atkinesin-13A Modulates Cell-Wall Synthesis and Cell Expansion in via the THESEUS1 Pathway
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Dopamine Signaling Leads to Loss of Polycomb Repression and Aberrant Gene Activation in Experimental Parkinsonism
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Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation
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Bipartite Recognition of DNA by TCF/Pangolin Is Remarkably Flexible and Contributes to Transcriptional Responsiveness and Tissue Specificity of Wingless Signaling
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The Olfactory Transcriptomes of Mice
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Muscular Dystrophy-Associated and Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization
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Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in
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Evidence for Widespread Positive and Negative Selection in Coding and Conserved Noncoding Regions of
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Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias
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Rejuvenation of Meiotic Cohesion in Oocytes during Prophase I Is Required for Chiasma Maintenance and Accurate Chromosome Segregation
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Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals
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Local Effect of Enhancer of Zeste-Like Reveals Cooperation of Epigenetic and -Acting Determinants for Zygotic Genome Rearrangements
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A Genetic Assay for Transcription Errors Reveals Multilayer Control of RNA Polymerase II Fidelity
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Translational Regulation of the DOUBLETIME/CKIδ/ε Kinase by LARK Contributes to Circadian Period Modulation
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Eliminating Both Canonical and Short-Patch Mismatch Repair in Suggests a New Meiotic Recombination Model
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tRNA Modifying Enzymes, NSUN2 and METTL1, Determine Sensitivity to 5-Fluorouracil in HeLa Cells
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Requirement for Drosophila SNMP1 for Rapid Activation and Termination of Pheromone-Induced Activity
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Co-regulated Transcripts Associated to Cooperating eSNPs Define Bi-fan Motifs in Human Gene Networks
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Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure
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Role for Circadian Clock Genes in Seasonal Timing: Testing the Bünning Hypothesis
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The Tandem Repeats Enabling Reversible Switching between the Two Phases of β-Lactamase Substrate Spectrum
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The Association of the Vanin-1 N131S Variant with Blood Pressure Is Mediated by Endoplasmic Reticulum-Associated Degradation and Loss of Function
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Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the Type 2 Diabetes GWAS Locus
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Regulation of Flowering by the Histone Mark Readers MRG1/2 via Interaction with CONSTANS to Modulate Expression
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The Actomyosin Machinery Is Required for Retinal Lumen Formation
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Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus
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Hidden Diversity in Honey Bee Gut Symbionts Detected by Single-Cell Genomics
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Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria
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Causal Variation in Yeast Sporulation Tends to Reside in a Pathway Bottleneck
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Genome Wide Association Studies Using a New Nonparametric Model Reveal the Genetic Architecture of 17 Agronomic Traits in an Enlarged Maize Association Panel
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Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers
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WC-1 Recruits SWI/SNF to Remodel and Initiate a Circadian Cycle
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Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing
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Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels
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Differential Management of the Replication Terminus Regions of the Two Chromosomes during Cell Division
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Obesity-Linked Homologues and Establish Meal Frequency in
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Derlin-1 Regulates Mutant VCP-Linked Pathogenesis and Endoplasmic Reticulum Stress-Induced Apoptosis
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Stress-Induced Nuclear RNA Degradation Pathways Regulate Yeast Bromodomain Factor 2 to Promote Cell Survival
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The MAPK p38c Regulates Oxidative Stress and Lipid Homeostasis in the Intestine
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Widespread Genome Reorganization of an Obligate Virus Mutualist
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The Vip1 Inositol Polyphosphate Kinase Family Regulates Polarized Growth and Modulates the Microtubule Cytoskeleton in Fungi
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Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis
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GLD-4-Mediated Translational Activation Regulates the Size of the Proliferative Germ Cell Pool in the Adult Germ Line
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Differential Responses to Wnt and PCP Disruption Predict Expression and Developmental Function of Conserved and Novel Genes in a Cnidarian

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