Flush, rosacea, alebo červenanie –  pochopenie rozdielov


Autoři: S. M. Agouba;  P. Hyrdel;  R. Hyrdel
Působiště autorů: Gastroenterology Clinic, Department of Internal Medicine, Jes­senius Faculty of Medicine and University Hospital Martin, Slovak Republic
Vyšlo v časopise: Gastroent Hepatol 2016; 70(4): 346-352
Kategorie: Kapitoly z interní medicíny: přehledová práce
doi: 10.14735/amgh2016346

Souhrn

Výraz „flush” je označenie začervenania pokožky pri rozličných fyziologických a patologických zdravotných stavoch. Flush však môže byť spôsobený aj závažnými príčinami. Veľké množstvo pacientov s nekarcinoidovým flushom bolo odoslaných na našu kliniku pre podozrenie na karcinoid. Väčšina z pacientov už v tom čase podstúpila mnohé biochemické a rádiologické vyšetrenia, bez praktického prínosu a finančne zaťažujúce. Sme si vedomí, že rozdiel medzi karcinoidovým a nekarcinoidovým flushom je stále viac zastretý.

Ciele:
V našom prehľade sme sa zamerali na diferenciáciu karcinoidového flushu a jeho odlíšenie od iných príčin, ktoré môžu imitovať karcinoidový syndróm, najmä rosacea a menopauzálny flush. Zameriavame sa stručne na základnú patofyziológiu flushu. Cieľom prehľadu je pomôcť lekárom stretávajúcim sa s flushom. Vymyslieť užitočný diagnostický algoritmus, ktorý pomôže objasniť jeho etiológiu a určiť nutnosť použitia multidisciplinárneho postupu. Zdôrazňujeme však, že lekár by mal vždy posudzovať každého pacienta individuálne.

Výsledky:
Na odlíšenie karcinoidového a nonkarcinoidového flushu sme sa pokúsili zaviesť diagnostický algoritmus za účelom zjednodušenia manažmentu týchto pacientov. Liečba je nad rozsah tejto práce.

Kľúčové slová:
flush – karcinoid – neuroendokrinný – menopauza – rosacea – patofyziológia – algoritmus

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 Doručeno:
19. 5. 2016

Přijato:
6. 6. 2016


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Štítky
Dětská gastroenterologie Gastroenterologie a hepatologie Chirurgie všeobecná

Článek vyšel v časopise

Gastroenterologie a hepatologie

Číslo 4

2016 Číslo 4

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