Flush, rosacea, alebo červenanie – pochopenie rozdielov
Autoři:
S. M. Agouba; P. Hyrdel; R. Hyrdel
Působiště autorů:
Gastroenterology Clinic, Department of Internal Medicine, Jessenius Faculty of Medicine and University Hospital Martin, Slovak Republic
Vyšlo v časopise:
Gastroent Hepatol 2016; 70(4): 346-352
Kategorie:
Kapitoly z interní medicíny: přehledová práce
doi:
https://doi.org/10.14735/amgh2016346
Souhrn
Výraz „flush” je označenie začervenania pokožky pri rozličných fyziologických a patologických zdravotných stavoch. Flush však môže byť spôsobený aj závažnými príčinami. Veľké množstvo pacientov s nekarcinoidovým flushom bolo odoslaných na našu kliniku pre podozrenie na karcinoid. Väčšina z pacientov už v tom čase podstúpila mnohé biochemické a rádiologické vyšetrenia, bez praktického prínosu a finančne zaťažujúce. Sme si vedomí, že rozdiel medzi karcinoidovým a nekarcinoidovým flushom je stále viac zastretý.
Ciele:
V našom prehľade sme sa zamerali na diferenciáciu karcinoidového flushu a jeho odlíšenie od iných príčin, ktoré môžu imitovať karcinoidový syndróm, najmä rosacea a menopauzálny flush. Zameriavame sa stručne na základnú patofyziológiu flushu. Cieľom prehľadu je pomôcť lekárom stretávajúcim sa s flushom. Vymyslieť užitočný diagnostický algoritmus, ktorý pomôže objasniť jeho etiológiu a určiť nutnosť použitia multidisciplinárneho postupu. Zdôrazňujeme však, že lekár by mal vždy posudzovať každého pacienta individuálne.
Výsledky:
Na odlíšenie karcinoidového a nonkarcinoidového flushu sme sa pokúsili zaviesť diagnostický algoritmus za účelom zjednodušenia manažmentu týchto pacientov. Liečba je nad rozsah tejto práce.
Kľúčové slová:
flush – karcinoid – neuroendokrinný – menopauza – rosacea – patofyziológia – algoritmus
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Doručeno:
19. 5. 2016
Přijato:
6. 6. 2016
Zdroje
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