Different roles of integrin-β1 and integrin-αv for type IV secretion of CagA versus cell elongation phenotype and cell lifting by Helicobacter pylori

English version

Autoři: Wolfgang Fischer ^aff001; Rainer Haas ^aff001
Působiště autorů: Medical Microbiology and Hospital Epidemiology, Max von Pettenkofer Institute, Faculty of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany ^aff001; German Center for Infection Research (DZIF), Ludwig-Maximilians-University Munich, Munich, Germany ^aff002
Vyšlo v časopise: Different roles of integrin-β1 and integrin-αv for type IV secretion of CagA versus cell elongation phenotype and cell lifting by Helicobacter pylori. PLoS Pathog 16(6): e32767. doi:10.1371/journal.ppat.1008564
Kategorie: Formal Comment
doi: https://doi.org/10.1371/journal.ppat.1008564

Zdroje

1. Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, et al. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature. 2007;449(7164):862–6. doi: 10.1038/nature06187 17943123

2. Jimenez-Soto LF, Kutter S, Sewald X, Ertl C, Weiss E, Kapp U, et al. Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner. PLoS Pathog. 2009;5(12):e1000684. doi: 10.1371/journal.ppat.1000684 19997503

3. Buss M, Tegtmeyer N, Schnieder J, Dong X, Li J, Springer TA, et al. Specific high affinity interaction of Helicobacter pylori CagL with integrin alphaV beta6 promotes type IV secretion of CagA into human cells. Febs J. 2019;286(20):3980–97. Epub 2019/06/15. doi: 10.1111/febs.14962 31197920

4. Königer V, Holsten L, Harrison U, Busch B, Loell E, Zhao Q, et al. Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA. Nat Microbiol. 2016;2 : 16188–99. nmicrobiol2016188 [pii]; doi: 10.1038/nmicrobiol.2016.188 27748756

5. Javaheri A, Kruse T, Moonens K, Mejias-Luque R, Debraekeleer A, Asche CI, et al. Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs. Nat Microbiol. 2016;2 : 16189. nmicrobiol2016189 [pii]; doi: 10.1038/nmicrobiol.2016.189 27748768

6. Zhao Q, Busch B, Jimenez-Soto LF, Ishikawa-Ankerhold H, Massberg S, Terradot L, et al. Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation. PLoS Pathog. 2018;14(10):e1007359. Epub 2018/10/27. doi: 10.1371/journal.ppat.1007359 30365569; PubMed Central PMCID: PMC6231679.

7. Bauer B, Moese S, Bartfeld S, Meyer TF, Selbach M. Analysis of cell type-specific responses mediated by the type IV secretion system of Helicobacter pylori. Infect Immun. 2005;73(8):4643–52. doi: 10.1128/IAI.73.8.4643-4652.2005 16040977

Článek Various miRNAs compensate the role of miR-122 on HCV replication

Článek Novel partiti-like viruses are conditional mutualistic symbionts in their normal lepidopteran host, African armyworm, but parasitic in a novel host, Fall armyworm

Článek Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions

Článek Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation

Článek Exploring potential of vaginal Lactobacillus isolates from South African women for enhancing treatment for bacterial vaginosis

Článek Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB

Článek Cellular plasticity of pathogenic fungi during infection

Článek Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7

Článek Transmission modes affect the population structure of potato virus Y in potato

Článek A secreted LysM effector protects fungal hyphae through chitin-dependent homodimer polymerization

Článek Potent, specific MEPicides for treatment of zoonotic staphylococci

Článek A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection