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ReklamaPLOS Genetics - Číslo 10/2019
Research Article
1008067HRPK-1, a conserved KH-domain protein, modulates microRNA activity during Caenorhabditis elegans developmentLi Li, Isana Veksler-Lublinsky, Anna Zinovyeva
1008096Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant miceZhaoyang Liu, Garrett W. D. Easson, Jingjing Zhao, Nadja Makki, Nadav Ahituv, Matthew J. Hilton, Simon Y. Tang, Ryan S. Gray
1008223Local adaptation drives the diversification of effectors in the fungal wheat pathogen Parastagonospora nodorum in the United StatesJonathan K. Richards, Eva H. Stukenbrock, Jessica Carpenter, Zhaohui Liu, Christina Cowger, Justin D. Faris, Timothy L. Friesen
1008232Biofilm-associated toxin and extracellular protease cooperatively suppress competitors in Bacillus subtilis biofilmsKazuo Kobayashi, Yukako Ikemoto
1008263Mutations of the Bacillus subtilis YidC1 (SpoIIIJ) insertase alleviate stress associated with σM-dependent membrane protein overproductionHeng Zhao, Ankita J. Sachla, John D. Helmann
1008279A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigsIn-Cheol Cho, Hee-Bok Park, Jin Seop Ahn, Sang-Hyun Han, Jae-Bong Lee, Hyun-Tae Lim, Chae-Kyoung Yoo, Eun-Ji Jung, Dong-Hwan Kim, Wu-Sheng Sun, Yuliaxis Ramayo-Caldas, Sang-Geum Kim, Yong-Jun Kang, Yoo-Kyung Kim, Hyun-Sook Shin, Pil-Nam Seong, In-Sul Hwang, Beom-Young Park, Seongsoo Hwang, Sung-Soo Lee, Youn-Chul Ryu, Jun-Heon Lee, Moon-Suck Ko, Kichoon Lee, Göran Andersson, Miguel Pérez-Enciso, Jeong-Woong Lee
1008341INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior in Caenorhabditis elegansLisa Voelker, Bishal Upadhyaya, Denise M. Ferkey, Sarah Woldemariam, Noelle D. L’Etoile, Ithai Rabinowitch, Jihong Bai
1008353MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial agingLouise A. C. Millard, Marcus R. Munafò, Kate Tilling, Robyn E. Wootton, George Davey Smith
1008354Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequencyPeiheng Gan, Michaela Patterson, Alexa Velasquez, Kristy Wang, Di Tian, Jolene J. Windle, Ge Tao, Daniel P. Judge, Takako Makita, Thomas J. Park, Henry M. Sucov
1008355Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human CellsEdwige B. Garcin, Stéphanie Gon, Meghan R. Sullivan, Gregory J. Brunette, Anne De Cian, Jean-Paul Concordet, Carine Giovannangeli, Wilhelm G. Dirks, Sonja Eberth, Kara A. Bernstein, Rohit Prakash, Maria Jasin, Mauro Modesti
1008356Ataxin2 functions via CrebA to mediate Huntingtin toxicity in circadian clock neuronsFangke Xu, Elzbieta Kula-Eversole, Marta Iwanaszko, Chunghun Lim, Ravi Allada
1008357Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleftLulin Huang, Zhonglin Jia, Yi Shi, Qin Du, Jiayu Shi, Ziyan Wang, Yandong Mou, Qingwei Wang, Bihe Zhang, Qing Wang, Shi Ma, He Lin, Shijun Duan, Bin Yin, Yansong Lin, Yiru Wang, Dan Jiang, Fang Hao, Lin Zhang, Haixin Wang, Suyuan Jiang, Huijuan Xu, Chengwei Yang, Chenghao Li, Jingtao Li, Bing Shi, Zhenglin Yang
1008362The quorum sensing transcription factor AphA directly regulates natural competence in Vibrio choleraeJames R. J. Haycocks, Gemma Z. L. Warren, Lucas M. Walker, Jennifer L. Chlebek, Triana N. Dalia, Ankur B. Dalia, David C. Grainger
1008401A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoelsAneesha G. Tewari, Jared H. Owen, Christian P. Petersen, Daniel E. Wagner, Peter W. Reddien
1008405Causal relationships between obesity and the leading causes of death in women and menJenny C. Censin, Sanne A. E. Peters, Jonas Bovijn, Teresa Ferreira, Sara L. Pulit, Reedik Mägi, Anubha Mahajan, Michael V. Holmes, Cecilia M. Lindgren
1008408Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx miceLuca Madaro, Alessio Torcinaro, Marco De Bardi, Federica F. Contino, Mattia Pelizzola, Giuseppe R. Diaferia, Giulia Imeneo, Marina Bouchè, Pier Lorenzo Puri, Francesca De Santa
1008409Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomesAntonio Capalbo, Roberto Alonso Valero, Jorge Jimenez-Almazan, Pere Mir Pardo, Marco Fabiani, David Jiménez, Carlos Simon, Julio Rodriguez Martin
1008410Manipulating mtDNA in vivo reprograms metabolism via novel response mechanismsDiana Bahhir, Cagri Yalgin, Liina Ots, Sampsa Järvinen, Jack George, Alba Naudí, Tatjana Krama, Indrikis Krams, Mairi Tamm, Ana Andjelković, Eric Dufour, Jose M. González de Cózar, Mike Gerards, Mikael Parhiala, Reinald Pamplona, Howard T. Jacobs, Priit Jõers
1008411TSEN54 missense variant in Standard Schnauzers with leukodystrophyTheresa Störk, Jasmin Nessler, Linda Anderegg, Enrice Hünerfauth, Isabelle Schmutz, Vidhya Jagannathan, Kaisa Kyöstilä, Hannes Lohi, Wolfgang Baumgärtner, Andrea Tipold, Tosso Leeb
1008412Centromeric SMC1 promotes centromer clustering and stabilizes meiotic homolog pairingTalia Hatkevich, Vincent Boudreau, Thomas Rubin, Paul S. Maddox, Jean-René Huynh, Jeff Sekelsky
1008416A RAPGEF6 variant constitutes a major risk factor for laryngeal paralysis in dogsSheida Hadji Rasouliha, Laura Barrientos, Linda Anderegg, Carina Klesty, Jessica Lorenz, Lucie Chevallier, Vidhya Jagannathan, Sarah Rösch, Tosso Leeb
1008419GPCR-mediated glucose sensing system regulates light-dependent fungal development and mycotoxin productionThaila Fernanda dos Reis, Laura Mellado, Jessica M. Lohmar, Lilian Pereira Silva, Jing-Jiang Zhou, Ana M. Calvo, Gustavo H. Goldman, Neil A. Brown
1008423Kinetochore-associated Stu2 promotes chromosome biorientation in vivoMatthew P. Miller, Rena K. Evans, Alex Zelter, Elisabeth A. Geyer, Michael J. MacCoss, Luke M. Rice, Trisha N. Davis, Charles L. Asbury, Sue Biggins
1008424Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in miceJaroslawna Meister, Derek B. J. Bone, Grzegorz Godlewski, Ziyi Liu, Regina J. Lee, Sergey A. Vishnivetskiy, Vsevolod V. Gurevich, Danielle Springer, George Kunos, Jürgen Wess
1008425NusG prevents transcriptional invasion of H-NS-silenced genesLionello Bossi, Mathilde Ratel, Camille Laurent, Patricia Kerboriou, Andrew Camilli, Eric Eveno, Marc Boudvillain, Nara Figueroa-Bossi
1008430The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeastKelsey L. Lynch, Gina M. Alvino, Elizabeth X. Kwan, Bonita J. Brewer, M. K. Raghuraman
1008431Bayesian multivariate reanalysis of large genetic studies identifies many new associationsMichael C. Turchin, Matthew Stephens
1008434Bacillus subtilis PgcA moonlights as a phosphoglucosamine mutase in support of peptidoglycan synthesisVaidehi Patel, Katherine A. Black, Kyu Y. Rhee, John D. Helmann
1008435Protease-associated import systems are widespread in Gram-negative bacteriaRhys Grinter, Pok Man Leung, Lakshmi C. Wijeyewickrema, Dene Littler, Simone Beckham, Robert N. Pike, Daniel Walker, Chris Greening, Trevor Lithgow
1008438Spatiotemporal cytoskeleton organizations determine morphogenesis of multicellular trichomes in tomatoJiang Chang, Zhijing Xu, Meng Li, Meina Yang, Haiyang Qin, Jie Yang, Shuang Wu
1008439Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expressionParmanand Malvi, Radoslav Janostiak, Arvindhan Nagarajan, Guoping Cai, Narendra Wajapeyee
1008441Histone deposition promotes recombination-dependent replication at arrested forksJulien Hardy, Dingli Dai, Anissia Ait Saada, Ana Teixeira-Silva, Louise Dupoiron, Fatemeh Mojallali, Karine Fréon, Francoise Ochsenbein, Brigitte Hartmann, Sarah Lambert
1008443Synergistic action of the transcription factors Krüppel homolog 1 and Hairy in juvenile hormone/Methoprene-tolerant-mediated gene-repression in the mosquito Aedes aegyptiTusar T. Saha, Sourav Roy, Gaofeng Pei, Wei Dou, Zhen Zou, Alexander S. Raikhel
1008444Low affinity binding sites in an activating CRM mediate negative autoregulation of the Drosophila Hox gene UltrabithoraxRebecca K. Delker, Vikram Ranade, Ryan Loker, Roumen Voutev, Richard S. Mann
1008445A novel system of bacterial cell division arrest implicated in horizontal transmission of an integrative and conjugative elementSotaro Takano, Kohei Fukuda, Akiko Koto, Ryo Miyazaki
1008448PilT and PilU are homohexameric ATPases that coordinate to retract type IVa piliJennifer L. Chlebek, Hannah Q. Hughes, Aleksandra S. Ratkiewicz, Rasman Rayyan, Joseph Che-Yen Wang, Brittany E. Herrin, Triana N. Dalia, Nicolas Biais, Ankur B. Dalia
1008451The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progressionAdam Olson, Vien Le, Joseph Aldahl, Eun-Jeong Yu, Erika Hooker, Yongfeng He, Dong-Hong Lee, Won Kyung Kim, Robert D. Cardiff, Joseph Geradts, Zijie Sun
1008453Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycleXue Li, Sudhir Kumar, Marina McDew-White, Meseret Haile, Ian H. Cheeseman, Scott Emrich, Katie Button-Simons, Francois Nosten, Stefan H. I. Kappe, Michael T. Ferdig, Tim J. C. Anderson, Ashley M. Vaughan
1008460A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicingTao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty, Sebastian Fröhler, Clemens Grimm, Yuhui Hu, Bernhard Schaefke, Liang Fang, Min Zhang, Nadine Kraemer, Angela M. Kaindl, Utz Fischer, Wei Chen
1008464CRISPR editing of sftb-1/SF3B1 in Caenorhabditis elegans allows the identification of synthetic interactions with cancer-related mutations and the chemical inhibition of splicingXènia Serrat, Dmytro Kukhtar, Eric Cornes, Anna Esteve-Codina, Helena Benlloch, Germano Cecere, Julián Cerón
10084651008466Paralog buffering contributes to the variable essentiality of genes in cancer cell linesBarbara De Kegel, Colm J. Ryan
1008474Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenanceZhenxing Liu, Christine A. Tabuloc, Yongbo Xue, Yao Cai, Pearson Mcintire, Ye Niu, Vu H. Lam, Joanna C. Chiu, Yong Zhang
1008479Duplicate divergence of two bacterial small heat shock proteins reduces the demand for Hsp70 in refolding of substratesIgor Obuchowski, Artur Piróg, Milena Stolarska, Bartłomiej Tomiczek, Krzysztof Liberek
Topic Page
1008271Viral quasispeciesEsteban Domingo, Celia Perales
Perspective
1008372Mck1 kinase is a new player in the DNA damage checkpoint pathwayNerea Sanvisens Delgado, David P. Toczyski
Expression of Concern
Editorial
1008437Evaluating the strength of genetic results: Risks and responsibilitiesGregory S. Barsh, Gregory M. Cooper, Gregory P. Copenhaver, Giorgio Sirugo, Hua Tang, Scott M. Williams
PLOS Genetics
2019 Číslo 10
Nejčtenější v tomto čísle- Spatiotemporal cytoskeleton organizations determine morphogenesis of multicellular trichomes in tomato
- Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression
- Synergistic action of the transcription factors Krüppel homolog 1 and Hairy in juvenile hormone/Methoprene-tolerant-mediated gene-repression in the mosquito Aedes aegypti
- TSEN54 missense variant in Standard Schnauzers with leukodystrophy
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