#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Long‑term Response of Liver Metastases of Breast Cancer to Capecitabine –  Case Report


Authors: D. Macková
Authors place of work: Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno
Published in the journal: Klin Onkol 2010; 23(1): 46-48
Category: Kazuistiky

Summary

A case report of a patient with HER2- positive liver metastases of breast cancer. Partial regression was reached during chemotherapy, which was further stabilized by trastuzumab. Resection of the metastases was performed after progression. Capecitabine was started after the occurrence of new multiple lesions; complete regression was reached, which has now lasted over three years with continued capecitabine treatment.

Key words:
breast cancer –  liver metastases


Zdroje

1. Marty M, Cognetti F, Maraninchi D et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2- positive metastatic breast cancer administered as first‑line treatment: the M77001 study group. J Clin Oncol 2005; 23(19): 4265– 4274.

2. Carlini M, Lonardo MT, Carboni F et al. Liver metastases from breast cancer. Results of surgical resection. Hepatogastroenterology 2002; 49(48): 1597– 1601.

3. Lermite E, Marzano E, Chéreau E et al. Surgical resection of liver metastases from breast cancer. Surg Oncol 2009. [Epub ahead of print]

4. Stockler MR, Sourjina T, Grimison P et al. A randomized trial of capecitabine given intermittently rather than continuously compared to classical CMF as first‑line chemotherapy for advanced breast cancer. J Clin Oncol 2007; 25 (Suppl): Abstract 1031.

5. Miles D, Vukelja S, Moiseyenko JA et al. Survival benefit with capecitabine/ docetaxel versus docetaxel alone: Analysis of therapy in a randomized phase III trial. Clinical Breast Cancer 2004; 5(4): 273– 278.

6. Verma S, Wong NS, Trudeau M et al. Survival Differences Observed in Metastatic Breast Cancer Patients Treated With Capecitabine When Compared With Vinorelbine After Pretreatment With Anthracycline and Taxane. Am J Clin Oncol 2007; 30: 297– 302.

7. von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2- positive advanced breast cancer: a german breast group 26/ breast international group 03– 05 study. J Clin Oncol 2009; 27(12): 1999– 2006.

8. Cameron D, Casey M, Press M et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and bio­marker analyses. Breast Cancer Res Treat 2008; 112(3): 533– 543.

Štítky
Dětská onkologie Chirurgie všeobecná Onkologie

Článek vyšel v časopise

Klinická onkologie

Číslo 1

2010 Číslo 1
Nejčtenější tento týden
Nejčtenější v tomto čísle
Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

Svět praktické medicíny 1/2024 (znalostní test z časopisu)
nový kurz

Koncepce osteologické péče pro gynekology a praktické lékaře
Autoři: MUDr. František Šenk

Sekvenční léčba schizofrenie
Autoři: MUDr. Jana Hořínková

Hypertenze a hypercholesterolémie – synergický efekt léčby
Autoři: prof. MUDr. Hana Rosolová, DrSc.

Význam metforminu pro „udržitelnou“ terapii diabetu
Autoři: prof. MUDr. Milan Kvapil, CSc., MBA

Všechny kurzy
Kurzy Podcasty Doporučená témata Časopisy
Přihlášení
Zapomenuté heslo

Zadejte e-mailovou adresu, se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.

Přihlášení

Nemáte účet?  Registrujte se

#ADS_BOTTOM_SCRIPTS#