REAKCE ENDOTELU NA HYPOXII

Endothelial Responses to Hypoxia

In the last decade endothelium was shown to play an active role in regulating vascular homeostasis. This reviewfocuses on the endothelial reactions during pathological condition of hypoxia. Cascade of events leading toendothelial activation/dysfunction during hypoxia is described and consequences of our expanded understanding ofvascular biology for current clinical practice are summarised.

Key words:
hypoxia, endothelium, activation/dysfunction.