PLOS Genetics - Číslo 7/2020

Perspective

1008833
Predicting longevity responses to dietary restriction: A stepping stone toward precision geroscience

Maria C. Perez-Matos, William B. Mair

1008842
A FAS solution to a DEAD case

Alexandra Gruss

1008914
Not too long, not too short: Goldilocks principle of eye size

Rachel W. Kuchtey


Review

1008872
Double-edged sword: The evolutionary consequences of the epigenetic silencing of transposable elements

Jae Young Choi, Yuh Chwen G. Lee

1008898
Advances and challenges in genetic technologies to produce single-sex litters

Charlotte Douglas, James M. A. Turner


Editorial

1008950
Mixed methods

David J. Balding, Gregory S. Barsh, Gregory P. Copenhaver, Chengqi Yi


Topic Page

1008918
Holocentric chromosomes

Mauro Mandrioli, Gian Carlo Manicardi


Research Article

1008484
Spontaneous mutations that confer resistance to 2-deoxyglucose act through Hxk2 and Snf1 pathways to regulate gene expression and HXT endocytosis

Samantha R. Soncini, Dakshayini G. Chandrashekarappa, David A. Augustine, Kenny P. Callahan, Allyson F. O’Donnell, Martin C. Schmidt

1008610
IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein

Erin A. Wall, Nadim Majdalani, Susan Gottesman

1008611
A non-canonical RNAi pathway controls virulence and genome stability in Mucorales

Carlos Pérez-Arques, María Isabel Navarro-Mendoza, Laura Murcia, Eusebio Navarro, Victoriano Garre, Francisco Esteban Nicolás

1008713
TaTLP1 interacts with TaPR1 to contribute to wheat defense responses to leaf rust fungus

Fei Wang, Shitao Yuan, Wenyue Wu, Yiqing Yang, Zhongchi Cui, Haiyan Wang, Daqun Liu

1008779
The DEAD-box RNA helicase CshA is required for fatty acid homeostasis in Staphylococcus aureus

Vanessa Khemici, Julien Prados, Bianca Petrignani, Benjamin Di Nolfi, Elodie Bergé, Caroline Manzano, Caroline Giraud, Patrick Linder

1008785
Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits

Andrew D. Bretherick, Oriol Canela-Xandri, Peter K. Joshi, David W. Clark, Konrad Rawlik, Thibaud S. Boutin, Yanni Zeng, Carmen Amador, Pau Navarro, Igor Rudan, Alan F. Wright, Harry Campbell, Veronique Vitart, Caroline Hayward, James F. Wilson, Albert Tenesa, Chris P. Ponting, J. Kenneth Baillie, Chris Haley

1008812
Epistatic interactions between PHOTOPERIOD1, CONSTANS1 and CONSTANS2 modulate the photoperiodic response in wheat

Lindsay M. Shaw, Chengxia Li, Daniel P. Woods, Maria A. Alvarez, Huiqiong Lin, Mei Y. Lau, Andrew Chen, Jorge Dubcovsky

1008828
Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

Jeziel D. Damasceno, João Reis-Cunha, Kathryn Crouch, Dario Beraldi, Craig Lapsley, Luiz R. O. Tosi, Daniella Bartholomeu, Richard McCulloch

1008835
Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila

Kelly Jin, Kenneth A. Wilson, Jennifer N. Beck, Christopher S. Nelson, George W. Brownridge, III, Benjamin R. Harrison, Danijel Djukovic, Daniel Raftery, Rachel B. Brem, Shiqing Yu, Mathias Drton, Ali Shojaie, Pankaj Kapahi, Daniel Promislow

1008856
Repression of tick microRNA-133 induces organic anion transporting polypeptide expression critical for Anaplasma phagocytophilum survival in the vector and transmission to the vertebrate host

Ellango Ramasamy, Vikas Taank, John F Anderson, Hameeda Sultana, Girish Neelakanta

1008882
Maize adaptation across temperate climates was obtained via expression of two florigen genes

Sara Castelletti, Aude Coupel-Ledru, Italo Granato, Carine Palaffre, Llorenç Cabrera-Bosquet, Chiara Tonelli, Stéphane D. Nicolas, François Tardieu, Claude Welcker, Lucio Conti

1008883
Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis

Taotao Li, Wei Lei, Ruiyuan He, Xiaoya Tang, Jifu Han, Lijuan Zou, Yanhai Yin, Honghui Lin, Dawei Zhang

1008884
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP

Flora Szeri, Stefan Lundkvist, Sylvia Donnelly, Udo F. H. Engelke, Kyu Rhee, Charlene J. Williams, John P. Sundberg, Ron A. Wevers, Ryan E. Tomlinson, Robert S. Jansen, Koen van de Wetering

1008900
A novel allele of ASY3 is associated with greater meiotic stability in autotetraploid Arabidopsis lyrata

Paul J. Seear, Martin G. France, Catherine L. Gregory, Darren Heavens, Roswitha Schmickl, Levi Yant, James D. Higgins

1008901
A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons

Derrick J. Morton, Binta Jalloh, Lily Kim, Isaac Kremsky, Rishi J. Nair, Khuong B. Nguyen, J. Christopher Rounds, Maria C. Sterrett, Brianna Brown, Thalia Le, Maya C. Karkare, Kathryn D. McGaughey, Shaoyi Sheng, Sara W. Leung, Milo B. Fasken, Kenneth H. Moberg, Anita H. Corbett

1008903
Protein-Protein interactions uncover candidate ‘core genes’ within omnigenic disease networks

Abhirami Ratnakumar, Nils Weinhold, Jessica C. Mar, Nadeem Riaz

1008904
PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions

Stefani Giacopazzi, Daniel Vong, Alice Devigne, Needhi Bhalla

1008907
The beta-1, 4-N-acetylglucosaminidase 1 gene, selected by domestication and breeding, is involved in cocoon construction of Bombyx mori

Chunlin Li, Xiaoling Tong, Weidong Zuo, Hai Hu, Gao Xiong, Minjin Han, Rui Gao, Yue Luan, Kunpeng Lu, Tingting Gai, Zhonghuai Xiang, Cheng Lu, Fangyin Dai

1008908
An expanded cell wall damage signaling network is comprised of the transcription factors Rlm1 and Sko1 in Candida albicans

Marienela Y. Heredia, Mélanie A. C. Ikeh, Deepika Gunasekaran, Karen A. Conrad, Sviatlana Filimonava, Dawn H. Marotta, Clarissa J. Nobile, Jason M. Rauceo

1008917
Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

Elodie Gazanion, Laurent Lacroix, Patrizia Alberti, Pratima Gurung, Sharon Wein, Mingpan Cheng, Jean-Louis Mergny, Ana Rita Gomes, Jose-Juan Lopez-Rubio

1008920
Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila

Lanikea B. King, Tamara Boto, Valentina Botero, Ari M. Aviles, Breanna M. Jomsky, Chevara Joseph, James A. Walker, Seth M. Tomchik

1008922
Unified inference of missense variant effects and gene constraints in the human genome

Yi-Fei Huang

1008923
RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases

Aurelio Reyes, Paola Favia, Sara Vidoni, Vittoria Petruzzella, Massimo Zeviani

1008924
Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions

Valentine Mosbach, David Viterbo, Stéphane Descorps-Declère, Lucie Poggi, Wilhelm Vaysse-Zinkhöfer, Guy-Franck Richard

1008931
Impact of insertion sequences on convergent evolution of Shigella species

Jane Hawkey, Jonathan M. Monk, Helen Billman-Jacobe, Bernhard Palsson, Kathryn E. Holt

1008933
CRL4Cdt2 ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation

Jia-Min Zhang, Jin-Xin Zheng, Yue-He Ding, Xiao-Ran Zhang, Fang Suo, Jing-Yi Ren, Meng-Qiu Dong, Li-Lin Du

1008944
Introns mediate post-transcriptional enhancement of nuclear gene expression in the green microalga Chlamydomonas reinhardtii

Thomas Baier, Nick Jacobebbinghaus, Alexander Einhaus, Kyle J. Lauersen, Olaf Kruse

1008949
The Paramecium histone chaperone Spt16-1 is required for Pgm endonuclease function in programmed genome rearrangements

Augustin de Vanssay, Amandine Touzeau, Olivier Arnaiz, Andrea Frapporti, Jamie Phipps, Sandra Duharcourt

1008964
The evolution and functional divergence of the histone H2B family in plants

Danhua Jiang, Michael Borg, Zdravko J. Lorković, Sean A. Montgomery, Akihisa Osakabe, Ramesh Yelagandula, Elin Axelsson, Frédéric Berger


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