Inherited thrombophilia and risk of venous thromboembolism in females in association with contraceptive use

Česká verze

Authors: Petr Dulíček
Authors place of work: IV. interní hematologická klinika LF UK a FN Hradec Králové
Published in the journal: Ceska Gynekol 2024; 89(5): 424-428
Category: Novinky z pohledu hematologa
doi: https://doi.org/10.48095/cccg2024424

Summary

Venous thromboembolism is a multifactorial dis ease and major cause of morbidity and mortality. Absolute risk of venous thromboembolism is less than 1 per 10,000 per year in women of reproductive age. Hormonal contraception is a common risk situation for venous thromboembolism in this part of the population. The risk of venous thrombosis depends on many factors, mainly female characteristics and also the type of contraception. Hematologists can help with the choice of contraception in females with inherited thrombophilia and females experiencing thrombosis. Intrauterine devices with levonorgestrel seem to be the best option in these settings.

Keywords:

thrombophilia – hormonal contraceptives – LNG-IUS

Zdroje

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ORCID autora

P. Dulíček 0000-0002-4899-760X

prof. MU Dr. Petr Dulíček, Ph.D.

IV. interní hematologická klinika

LF UK a FN Hradec Králové

Sokolská 581

500 05 Hradec Králové

petr.dulicek@fnhk.cz