Skin and soft tissue infections (SSTIs)

Česká verze

Authors: R. Gürlich ¹; V. Adámková ² ; J. Ulrych ³; H. Brodská ⁴; V. Janík ⁵; J. Lindner ⁶; E. Havel ⁷
Authors place of work: Chirurgická klinika FNKV a 3. LF Univerzity Karlovy přednosta: prof. MUDr. R. Gürlich, CSc. ¹; Klinická mikrobiologie a ATB centrum VFN Praha a 1. LF Univerzity Karlovy primář: MUDr. V. Adámková ²; I. chirurgická klinika VFN a 1. LF Univerzity Karlovy přednosta: prof. MUDr. Z. Krška, CSc. ³; Ústav lékařské biochemie a laboratorní diagnostiky přednosta: prof. MUDr. T. Zima, DrSc. ⁴; Radiodiagnostická klinika FNKV a 3. LF Univerzity Karlovy zastupující přednosta: MUDr. L. Večeřová ⁵; II. chirurgická klinika kardiovaskulární chirurgie VFN v Praze a 1. LF Univerzity Karlovy přednosta: prof. MUDr. J. Lindner, CSc. ⁶; Chirurgická klinika FNHK a LF HK přednosta: MUDr. M. Leško, Ph. D ⁷
Published in the journal: Rozhl. Chir., 2016, roč. 95, č. 4, s. 141-146.
Category: Souhrnné sdělení

Summary

Skin and Soft Tissue Infections (SSTIs) encompass a wide spectrum of inflammatory diseases of the skin, subcutis, fascia and muscles. Recent national trends indicate increasing rates of patients treated for these diagnoses at outpatient surgical department, but also of patients hospitalized with severe forms of SSTIs. Up to 90% fatality rates are reported in the literature for the most severe forms, resulting from underestimation of initial symptoms and therefore delayed onset of radical therapy only the phase of septic shock. The paper provides an interdisciplinary review of essential principles of the diagnosis and therapy of SSTIs, reflecting present knowledge supported by evidence-based medicine.

Key words:
skin and soft tissue infections –⁠ SSTIs –⁠ necrotizing fasciitis –⁠ diagnosis –⁠ therapy

Zdroje

1. Center for Drug Evaluation and Research (CDER). Uncomplicated and complicated skin and skin-structure infections –⁠ developing antimicrobial drugs for treatment. 1998. www.fda.gov/ cder/guidance/2566dft.pdf.

2. Sartelli M, Malangoni MA, May AK, et al. World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections. World Journal of Emergency Surgery 2014;9 : 57.

3. Goh T. Early diagnosis of necrotizing fasciitis. BJS, 2014;101:e119–e125.

4. Hakkarainen TW, Kopari NM, Pham TN, et al. Necrotizing soft tissue infections: review and current concepts in treatment, systems of care, and outcomes. Curr Probl Surg 2014;51 : 344−62.

5. Moran GJ, Abrahamian FM, Lovecchio F, et al. Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. J Emerg Med 2013;44 : 397−412.

6. Stevens DL, Bisno AL, Chambers HF, et al. Infectious Diseases Society of America. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis 201415;59 : 10−52.