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ReklamaPLOS Pathogens - Číslo 12/2019
Research Article
1007780A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria triticiDiana Steinhauer, Marie Salat, Regula Frey, Andreas Mosbach, Torsten Luksch, Dirk Balmer, Rasmus Hansen, Stephanie Widdison, Grace Logan, Robert A. Dietrich, Gert H. J. Kema, Stephane Bieri, Helge Sierotzki, Stefano F. F. Torriani, Gabriel Scalliet
1007823A novel genetic circuitry governing hypoxic metabolic flexibility, commensalism and virulence in the fungal pathogen Candida albicansAnaïs Burgain, Émilie Pic, Laura Markey, Faiza Tebbji, Carol A. Kumamoto, Adnane Sellam
1007855Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growthDhritiman Samanta, Tatiana M. Clemente, Baleigh E. Schuler, Stacey D. Gilk
1007976Distinct rates and patterns of spread of the major HIV-1 subtypes in Central and East AfricaNuno R. Faria, Nicole Vidal, José Lourenco, Jayna Raghwani, Kim C. E. Sigaloff, Andy J. Tatem, David A. M. van de Vijver, Andrea-Clemencia Pineda-Peña, Rebecca Rose, Carole L. Wallis, Steve Ahuka-Mundeke, Jean-Jacques Muyembe-Tamfum, Jérémie Muwonga, Marc A. Suchard, Tobias F. Rinke de Wit, Raph L. Hamers, Nicaise Ndembi, Guy Baele, Martine Peeters, Oliver G. Pybus, Philippe Lemey, Simon Dellicour
1008001Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infectionDiana Hooker-Romero, Erin Mettert, Leah Schwiesow, David Balderas, Pablo A. Alvarez, Anadin Kicin, Azuah L. Gonzalez, Gregory V. Plano, Patricia J. Kiley, Victoria Auerbuch
1008006Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidenceVincenzo Torraca, Myrsini Kaforou, Jayne Watson, Gina M. Duggan, Hazel Guerrero-Gutierrez, Sina Krokowski, Michael Hollinshead, Thomas B. Clarke, Rafal J. Mostowy, Gillian S. Tomlinson, Vanessa Sancho-Shimizu, Abigail Clements, Serge Mostowy
1008064IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibodySimone I. Richardson, Bronwen E. Lambson, Andrew R. Crowley, Arman Bashirova, Cathrine Scheepers, Nigel Garrett, Salim Abdool Karim, Nonhlanhla N. Mkhize, Mary Carrington, Margaret E. Ackerman, Penny L. Moore, Lynn Morris
1008066Linking the effects of helminth infection, diet and the gut microbiota with human whole-blood signaturesSoo Ching Lee, Mei San Tang, Alice V. Easton, Joseph Cooper Devlin, Ling Ling Chua, Ilseung Cho, Foong Ming Moy, Tsung Fei Khang, Yvonne A. L. Lim, P’ng Loke
1008082IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodiesWenwen Bi, Wei Xu, Liang Cheng, Jing Xue, Qian Wang, Fei Yu, Shuai Xia, Qi Wang, Guangming Li, Chuan Qin, Lu Lu, Lishan Su, Shibo Jiang
1008101Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistanceHelen E. McNeil, Ilyas Alav, Ricardo Corona Torres, Amanda E. Rossiter, Eve Laycock, Simon Legood, Inderpreet Kaur, Matthew Davies, Matthew Wand, Mark A. Webber, Vassiliy N. Bavro, Jessica M. A. Blair
1008109Childhood immune imprinting to influenza A shapes birth year-specific risk during seasonal H1N1 and H3N2 epidemicsKatelyn M. Gostic, Rebecca Bridge, Shane Brady, Cécile Viboud, Michael Worobey, James O. Lloyd-Smith
1008110Silencing of transcription factor encoding gene StTCP23 by small RNAs derived from the virulence modulating region of potato spindle tuber viroid is associated with symptom development in potatoSarina Bao, Robert A. Owens, Qinghua Sun, Hui Song, Yanan Liu, Andrew Leigh Eamens, Hao Feng, Hongzhi Tian, Ming-Bo Wang, Ruofang Zhang
1008115IL-23 supports host defense against systemic Candida albicans infection by ensuring myeloid cell survivalSelim Nur, Florian Sparber, Christina Lemberg, Eva Guiducci, Tiziano A. Schweizer, Pascale Zwicky, Burkhard Becher, Salomé LeibundGut-Landmann
1008121ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and typeLuca Schifanella, Susan W. Barnett, Massimiliano Bissa, Veronica Galli, Melvin N. Doster, Monica Vaccari, Georgia D. Tomaras, Xiaoying Shen, Sanjay Phogat, Ranajit Pal, David C. Montefiori, Celia C. LaBranche, Mangala Rao, Hung V. Trinh, Robyn Washington-Parks, Namal P. M. Liyanage, Dallas R. Brown, Frank Liang, Karin Loré, David J. Venzon, William Magnanelli, Michelle Metrinko, Josh Kramer, Matthew Breed, Galit Alter, Ruth M. Ruprecht, Genoveffa Franchini
10081291008136Neisseria gonorrhoeae Infects the Heterogeneous Epithelia of the Human Cervix Using Distinct MechanismsQian Yu, Liang-Chun Wang, Sofia Di Benigno, Scott D. Gray-Owen, Daniel C. Stein, Wenxia Song
1008139Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prionRomany Abskharon, Fei Wang, Alexandre Wohlkonig, Juxin Ruan, Sameh Soror, Gabriele Giachin, Els Pardon, Wenquan Zou, Giuseppe Legname, Jiyan Ma, Jan Steyaert
1008140IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosisDeepak Tripathi, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Madeline Kay McAllister, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
1008152Pathogenicity island excision during an infection by Salmonella enterica serovar Enteritidis is required for crossing the intestinal epithelial barrier in mice to cause systemic infectionCatalina Pardo-Roa, Geraldyne A. Salazar, Loreani Noguera, Francisco J. Salazar-Echegarai, Omar P. Vallejos, Isidora Suazo, Bárbara M. Schultz, Irenice Coronado-Arrazola, Alexis M. Kalergis, Susan M. Bueno
1008154Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse modelLorenz Loyola, Vasudevan Achuthan, Kathryn Gilroy, Gillian Borland, Anna Kilbey, Nancy Mackay, Margaret Bell, Jodie Hay, Sriram Aiyer, Dylan Fingerman, Rodrigo A. Villanueva, Ewan Cameron, Christine A. Kozak, Alan N. Engelman, James Neil, Monica J. Roth
1008155The alternative cap-binding complex is required for antiviral defense in vivoAnna Gebhardt, Valter Bergant, Daniel Schnepf, Markus Moser, Arno Meiler, Dieudonnée Togbe, Claire Mackowiak, Line Reinert, Søren R. Paludan, Bernhard Ryffel, Alexey Stukalov, Peter Staeheli, Andreas Pichlmair
1008156Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivationJungang Chen, Lu Dai, Alana Goldstein, Haiwei Zhang, Wei Tang, J. Craig Forrest, Steven R. Post, Xulin Chen, Zhiqiang Qin
1008157Therapeutic monoclonal antibody treatment protects nonhuman primates from severe Venezuelan equine encephalitis virus disease after aerosol exposureCrystal W. Burke, Jeffery W. Froude, Franco Rossi, Charles E. White, Crystal L. Moyer, Jane Ennis, M. Louise Pitt, Stephen Streatfield, R. Mark Jones, Konstantin Musiychuk, Jukka Kervinen, Larry Zeitlin, Vidadi Yusibov, Pamela J. Glass
1008161Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized miceJohn D. Ventura, Jagadish Beloor, Edward Allen, Tongyu Zhang, Kelsey A. Haugh, Pradeep D. Uchil, Christina Ochsenbauer, Collin Kieffer, Priti Kumar, Thomas J. Hope, Walther Mothes
1008165Cooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycansNelson R. Wu, Nathan I. Nicely, Esther M. Lee, Rachel K. Reed, Brian E. Watts, Fangping Cai, William E. Walkowicz, Baptiste Aussedat, Julia A. Jones, Amanda Eaton, Ashley M. Trama, S. Munir Alam, David C. Montefiori, Barton F. Haynes, Kevin O. Saunders
1008168Herpes simplex encephalitis in adult patients with MASP-2 deficiencyStéphanie Bibert, Jocelyne Piret, Mathieu Quinodoz, Emilie Collinet, Vincent Zoete, Olivier Michielin, Rafik Menasria, Pascal Meylan, Titus Bihl, Véronique Erard, Florence Fellmann, Carlo Rivolta, Guy Boivin, Pierre-Yves Bochud
1008173Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processingYoshiyuki Hakata, Jun Li, Takahiro Fujino, Yuki Tanaka, Rie Shimizu, Masaaki Miyazawa
1008174Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphomaLing Ding, Qing Zhu, Feng Zhou, Hongsheng Tan, Wenjia Xu, Chengling Pan, Caixia Zhu, Yuyan Wang, Hong Zhang, Wenwei Fu, Zhikang Qian, Zhenghong Yuan, Hongxi Xu, Fang Wei, Qiliang Cai
1008175Full-length human cytomegalovirus terminase pUL89 adopts a two-domain structure specific for DNA packagingJanine Theiß, Min Woo Sung, Andreas Holzenburg, Elke Bogner
1008177Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIVJennifer Currenti, Abha Chopra, Mina John, Shay Leary, Elizabeth McKinnon, Eric Alves, Mark Pilkinton, Rita Smith, Louise Barnett, Wyatt J. McDonnell, Michaela Lucas, Francine Noel, Simon Mallal, Joseph A. Conrad, Spyros Kalams, Silvana Gaudieri
1008180Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivoLawrence J. Tartaglia, Alexander Badamchi-Zadeh, Peter Abbink, Eryn Blass, Malika Aid, Makda S. Gebre, Zhenfeng Li, Kevin Clyde Pastores, Sebastien Trott, Siddhant Gupte, Rafael A. Larocca, Dan H. Barouch
1008183Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in IFNAR-/- miceStephen R. Welch, Jana M. Ritter, Anita K. McElroy, Jessica R. Harmon, JoAnn D. Coleman-McCray, Florine E. M. Scholte, Gary P. Kobinger, Éric Bergeron, Sherif R. Zaki, Stuart T. Nichol, Jessica R. Spengler, Christina F. Spiropoulou
1008185KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replicationBenjamin P. Johnston, Eric S. Pringle, Craig McCormick
1008186Toscana virus non-structural protein NSs acts as E3 ubiquitin ligase promoting RIG-I degradationGianni Gori Savellini, Gabriele Anichini, Claudia Gandolfo, Shibily Prathyumnan, Maria Grazia Cusi
1008192A role of hypoxia-inducible factor 1 alpha in Mouse Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latencyDarlah M. López-Rodríguez, Varvara Kirillov, Laurie T. Krug, Enrique A. Mesri, Samita Andreansky
1008193Molecular Anatomy of the Receptor Binding Module of a Bacteriophage Long Tail FiberMohammad Z. Islam, Andrei Fokine, Marthandan Mahalingam, Zhihong Zhang, Carmela Garcia-Doval, Mark J. van Raaij, Michael G. Rossmann, Venigalla B. Rao
1008198A Pseudomonas aeruginosa type VI secretion system regulated by CueR facilitates copper acquisitionYuying Han, Tietao Wang, Gukui Chen, Qinqin Pu, Qiong Liu, Yani Zhang, Linghui Xu, Min Wu, Haihua Liang
1008199Dengue virus reduces AGPAT1 expression to alter phospholipids and enhance infection in Aedes aegyptiThomas Vial, Wei-Lian Tan, Benjamin Wong Wei Xiang, Dorothée Missé, Eric Deharo, Guillaume Marti, Julien Pompon
1008207Dissemination of Chlamydia from the reproductive tract to the gastro-intestinal tract occurs in stages and relies on Chlamydia transport by host cellsSavannah E. Howe, Nita Shillova, Vjollca Konjufca
1008209Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopyFrauke Beilstein, Gary H. Cohen, Roselyn J. Eisenberg, Valérie Nicolas, Audrey Esclatine, David Pasdeloup
1008210RNA interference identifies domesticated viral genes involved in assembly and trafficking of virus-derived particles in ichneumonid waspsAnge Lorenzi, Marc Ravallec, Magali Eychenne, Véronique Jouan, Stéphanie Robin, Isabelle Darboux, Fabrice Legeai, Anne-Sophie Grenet-Gosselin, Mathieu Sicard, Don Stoltz, Anne-Nathalie Volkoff
1008213Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling and drug detoxification and are essential for parasite survivalBemnet A. Tedla, Javier Sotillo, Darren Pickering, Ramon M. Eichenberger, Stephanie Ryan, Luke Becker, Alex Loukas, Mark S. Pearson
1008216Novel RNA viruses associated with Plasmodium vivax in human malaria and Leucocytozoon parasites in avian diseaseJustine Charon, Matthew J. Grigg, John-Sebastian Eden, Kim A. Piera, Hafsa Rana, Timothy William, Karrie Rose, Miles P. Davenport, Nicholas M. Anstey, Edward C. Holmes
1008218Intra-host growth kinetics of dengue virus in the mosquito Aedes aegyptiMario Novelo, Matthew D. Hall, Damie Pak, Paul R. Young, Edward C. Holmes, Elizabeth A. McGraw
1008221PDGFRA defines the mesenchymal stem cell Kaposi’s sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environmentJulian Naipauer, Santas Rosario, Sachin Gupta, Courtney Premer, Omayra Méndez-Solís, Mariana Schlesinger, Virginia Ponzinibbio, Vaibhav Jain, Lauren Gay, Rolf Renne, Ho Lam Chan, Lluis Morey, Daria Salyakina, Martin Abba, Sion Williams, Joshua M. Hare, Pascal J. Goldschmidt-Clermont, Enrique A. Mesri
1008224Re-assessing the diversity of negative strand RNA viruses in insectsSimon Käfer, Sofia Paraskevopoulou, Florian Zirkel, Nicolas Wieseke, Alexander Donath, Malte Petersen, Terry C. Jones, Shanlin Liu, Xin Zhou, Martin Middendorf, Sandra Junglen, Bernhard Misof, Christian Drosten
1008228Novel replisome-associated proteins at cellular replication forks in EBV-transformed B lymphocytesHuanzhou Xu, Ramon D. Perez, Tiffany R. Frey, Eric M. Burton, Sudha Mannemuddhu, John D. Haley, Michael T. McIntosh, Sumita Bhaduri-McIntosh
1008232Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serumZoltán Attila Nagy, Dávid Szakács, Eszter Boros, Dávid Héja, Eszter Vígh, Noémi Sándor, Mihály Józsi, Gábor Oroszlán, József Dobó, Péter Gál, Gábor Pál
1008233Transcriptional regulation of a gonococcal gene encoding a virulence factor (L-lactate permease)Julio C. Ayala, William M. Shafer
1008239Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapyEric B. Wong, Brian Montoya, Maria Ferez, Colby Stotesbury, Luis J. Sigal
1008248Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucksManasa Suresh, Stefanie Czerwinski, Marta G. Murreddu, Bhaskar V. Kallakury, Ashika Ramesh, Severin O. Gudima, Stephan Menne
1008249Cross-talk between microglia and neurons regulates HIV latencyDavid Alvarez-Carbonell, Fengchun Ye, Nirmala Ramanath, Yoelvis Garcia-Mesa, Pamela E. Knapp, Kurt F. Hauser, Jonathan Karn
Pearls
1008090Small RNAs and extracellular vesicles: New mechanisms of cross-species communication and innovative tools for disease controlQiang Cai, Baoye He, Arne Weiberg, Amy H. Buck, Hailing Jin
1008095Protein–RNA interactions important for Plasmodium transmissionKelly T. Rios, Scott E. Lindner
1008097Human immunity to Toxoplasma gondiiDaniel Fisch, Barbara Clough, Eva-Maria Frickel
1008125Novel and emerging sources of Clostridioides difficile infectionNicholas A. Turner, Becky A. Smith, Sarah S. Lewis
1008162The pandemic Escherichia coli sequence type 131 strain is acquired even in the absence of antibiotic exposureGrant R. Whitmer, Ganga Moorthy, Mehreen Arshad
1008166A parasite’s take on the evolutionary cell biology of MICOSHassan Hashimi
Correction
1008200Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodiesCelia C. LaBranche, Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, Kevin O. Saunders, S. Munir Alam, Mattia Bonsignori, Mario J. Borgnia, Quentin J. Sattentau, Amanda Eaton, Kelli Greene, Hongmei Gao, Hua-Xin Liao, Wilton B. Williams, James Peacock, Haili Tang, Lautaro G. Perez, Robert J. Edwards, Thomas B. Kepler, Bette T. Korber, Peter D. Kwong, John R. Mascola, Priyamvada Acharya, Barton F. Haynes, David C. Montefiori
PLOS Pathogens
2019 Číslo 12
Nejčtenější v tomto čísle- Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth
- IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis
- The pandemic Escherichia coli sequence type 131 strain is acquired even in the absence of antibiotic exposure
- A role of hypoxia-inducible factor 1 alpha in Mouse Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency
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