TRANSPLANTACE VASKULARIZOVANÝCH KOMPOZITNÍCH ALLOGRAFTŮ. STRUČNÝ PŘEHLED SOUČASNÝCH POZNATKŮ


Autoři: M. Molitor
Působiště autorů: Department of Plastic Surgery, Hospital na Bulovce and the First Faculty of Medicine, Charles University, Czech Republic
Vyšlo v časopise: ACTA CHIRURGIAE PLASTICAE, 58, 1, 2016, pp. 18-28


Zdroje

1. www.handtransplant.com

2. www.handregistry.com

3. Alcorn JB. Memorandum. Use of VCA Grafts to Reconstruct the Abdominal Wall. January 13, 2015. Available from: http://optn.transplant.hrsa.gov/media/1159/vca_abdominal_wall_memo.pdf

4. Lanzetta M. – personal communication

5. Klapheke MM, Marcell C, Taliaferro G, Creamer B. Psychiatric assessment of candidates for hand transplantation. Microsurgery. 2000;20(8):453–7.

6. Klapheke M. Transplantation of the human hand: psychiatric considerations. Bull Menninger Clin.1999;63:159–173

7. Furr LA, Wiggins O, Cunningham M, Vasilic D, Brown CS, Banis JC Jr, Maldonado C, Perez-Abadia G, Barker JH.P sychosocial implications of disfigurement and the future of human face transplantation. Plast Reconstr Surg. 2007 Aug;120(2):559–65.

8. Zhang LC, Zhao YB, Hu WL. Ethical issues in penile transplantation. Asian J Androl. 2010 Nov;12(6):795–800.

9. Agich GJ, Siemionow M. Until they have faces: the ethics of facial allograft transplantation. J Med Ethics. 2014 Dec;115(6):333–42.

10. Barker JH, Furr A, McGuire S, Cunningham M, Wiggins O, Banis JC Jr. On the ethics of composite tissue allotransplantation (facial transplantation). Plast Reconstr Surg. 2007 Apr 15;119(5):1621–2.

11. Tobin GR, Breidenbach WC, Klapheke MM, Bentley FR, Pidwell DJ, Simmons PD. Ethical considerations in the early composite tissue allograft experience: a review of the Louisville Ethics Program. Transplant Proc. 2005 Mar;37(2):1392–5.

12. Clarke A, Simmons J, White P, Withey S, Butler PE. Attitudes to face transplantation: results of a public engagement exercise at the Royal Society Summer Science Exhibition. J Burn Care Res. 2006 May-Jun;27(3):394–8.

13. Mathes DW, Schlenker R, Ploplys E, Vedder N. A survey of North American hand surgeons on their current attitudes toward hand transplantation. J Hand Surg Am. 2009 May–Jun;34(5):808–14.

14. Mathes DW, Kumar N, Ploplys E. A survey of North American burn and plastic surgeons on their current attitudes toward facial transplantation. J Am Coll Surg. 2009 Jun;208(6):1051–8.e3.

15. Kiwanuka H, Bueno EM, Diaz-Siso JR, Sisk GC, Lehmann LS, Pomahac B. Evolution of ethical debate on face transplantation. Plast Reconstr Surg. 2013 Dec;132(6):1558–68.

16. Cendales L, Hardy MA. Immunologic considerations in composite tissue transplantation: overview. Microsurgery. 2000;20(8):412–9.

17. Barnes PJ. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin Sci (Lond). 1998 Jun;94(6):557–72.

18. Ransom JT. Mechanism of action of mycophenolate mofetil. Ther Drug Monit. 1995 Dec;17(6):681–4.

19. Clipstone NA, Crabtree GR. Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506. Ann N Y Acad Sci. 1993 Nov 30;696:20–30.

20. Hewitt CW, Black KS, Fraser LA, Howard EB, Martin DC, Achauer BM, Furnas DW. Composite tissue (limb) allografts in rats. I. Dose-dependent increase in survival with cyclosporine. Transplantation. 1985 Apr;39(4):360–4.

21. Black KS, Hewitt CW, Fraser LA, Howard EB, Martin DC, Achauer BM, Furnas DW. Composite tissue (limb) allografts in rats. II. Indefinite survival using low-dose cyclosporine. Transplantation. 1985 Apr;39(4):365–8.

22. European Multicentre Trial Group [No authors listed]. Cyclosporin in cadaveric renal transplantation: one-year follow-up of a multicentre trial. Lancet. 1983 Oct 29;2(8357):986–9.

23. Hricik DE, O’Toole MA, Schulak JA, Herson J. Steroid-free immunosuppression in cyclosporine-treated renal transplant recipients: a meta-analysis. J Am Soc Nephrol. 1993 Dec;4(6):1300–5.

24. Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem. 1998 Jul;31(5):335–40.

25. Lee WP, Yaremchuk MJ, Pan YC, Randolph MA, Tan CM, Weiland AJ. Relative antigenicity of components of a vascularized limb allograft. Plast Reconstr Surg. 1991 Mar;87(3):401–11.

26. Duquesnoy RJ. Is histocompatibility testing needed for composite tissue transplantation? Transplant Proc. 1998 Sep;30(6):2724–8.

27. Billingham R, Brendt L. Quantitative studies on tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease. Philos Trans R Soc. Lond Biol Sci. 1959;242:439

28. Mathes DW, Randolph MA, Solari MG, Nazzal JA, Nielsen GP, Arn JS, Sachs DH, Lee WP. Split tolerance to a composite tissue allograft in a swine model. Transplantation. 2003 Jan 15;75(1):25–31.

29. Schneeberger S, Gorantla VS, Hautz T, Pulikkottil B, Margreiter R, Lee WP. Immunosuppression and rejection in human hand transplantation. Transplant Proc. 2009 Mar;41(2):472–5.

30. Medical Tribune-World Wide report. Transplant is successful with a cadaver forearm. Med Trib Med News 1964; 5 (20): 1,38.

31. Zion’s Story: The Gift of hands. Available from: www.chop.edu/stories/zion-s-story-gift-hands#.VorgYrbhBkg

32. Lanzetta M, Perani D, Anchisi D, Rosén B, Danna M, Scifo P, Fazio F, Lundborg G. Early use of artificial sensibility in hand transplantation. Scand J Plast Reconstr Surg Hand Surg. 2004;38(2):106–11.

33. Pomahac B. – personal communication

34. Pomahac B, Pribaz JJ, Bueno EM, Sisk GC, Diaz-Siso JR, Chandawarkar A, Westvik TS, Malin EW, Eriksson E. Novel surgical technique for full face transplantation. Plast Reconstr Surg. 2012 Sep;130(3):549–55.

35. Pomahac B, Bueno EM, Sisk GC, Pribaz JJ. Current principles of facial allotransplantation: the Brigham and Women’s Hospital Experience. Plast Reconstr Surg. 2013 May;131(5):1069–76.

36. Soga S, Pomahac B, Wake N, Schultz K, Prior RF, Kumamaru K, Steigner ML, Mitsouras D, Signorelli J, Bueno EM, Enterline DS, Rybicki FJ. CT angiography for surgical planning in face transplantation candidates. AJNR Am J Neuroradiol. 2013 Oct;34(10):1873–81.

37. Gharb BB, Rampazzo A, Kutz JE, Bright L, Doumit G, Harter TB. Vascularization of the facial bones by the facial artery: implications for full face allotransplantation. Plast Reconstr Surg. 2014 May;133(5):1153–65.

38. Fischer S, Kueckelhaus M, Pauzenberger R, Bueno EM, Pomahac B. Functional outcomes of face transplantation. Am J Transplant. 2015 Jan;15(1):220–33.

39. Petruzzo P, Kanitakis J, Testelin S, Pialat JB, Buron F, Badet L, Thaunat O, Devauchelle B, Morelon E. Clinicopathological Findings of Chronic Rejection in a Face Grafted Patient. Transplantation. 2015 Dec;99(12):2644–50.

40. Carty MJ, Hivelin M, Dumontier C, Talbot SG, Benjoar MD, Pribaz JJ, Lantieri L, Pomahac B. Lessons learned from simultaneous face and bilateral hand allotransplantation. Plast Reconstr Surg. 2013 Aug;132(2):423–32.

41. Khalifian S, Brazio PS2, Mohan R2, Shaffer C2, Brandacher G3, Barth RN4, Rodriguez ED5. Facial transplantation: the first 9 years. Lancet. 2014 Dec 13;384(9960):2153–63.

42. Buncke HJ, Hoffman WY, Alpert BS, Gordon L, Stefani AE. Microvascular transplant of two free scalp flaps between identical twins. Plast Reconstr Surg. 1982 Nov;70(5):605–9.

43. Jiang HQ, Wang Y, Hu XB, Li YS, Li JS. Composite tissue allograft transplantation of cephalocervical skin flap and two ears. Plast Reconstr Surg. 2005 Mar;115(3):31e–35e.

44. Butler PEM. Composite tissue allograft transplantation of cephalocervical skin flap and two ears. Plast Reconstr Surg. 2005 Mar;115(3):discussion 36e–37e.

45. ABC News. Doctors in Texas perform historic skull and scalp transplant surgery [Internet]. Available from: http://www.abc.net.au/news/2015-06-05/doctors-perform-historic-skull-and-scalp-transplant-surgery/6524056

46. Buiret G, Rabilloud M, Combe C, Paliot H, Disant F, Céruse P. Larynx transplantation: laryngectomees´ opinion poll. Transplantation. 2007 Dec 27;84(12):1584–9.

47. Anthony JP, Argenta P, Trabulsy PP, Lin RY, Mathes SJ. The arterial anatomy of larynx transplantation: microsurgical revascularization of the larynx. Clin Anat. 1996;9(3):155–9.

48. Strome M, Wu J, Strome S, Brodsky G. A comparison of preservation techniques in a vascularized rat laryngeal transplant model. Laryngoscope. 1994 Jun;104(6 Pt 1):666–8.

49. Marie JP. Human Bilateral Laryngeal Reinnervation: Implications for Transplantation. Phoenix, AZ: American Laryngeal Association; 2009.

50. Marie JP, Dehesdin D, Ducastelle T, Senant J. Selective reinnervation of the abductor and adductor muscles of the canine larynx after recurrent nerve paralysis. Ann Otol Rhinol Laryngol. 1989 Jul;98:530–6.

51. van Lith-Bijl JT, Mahieu HF. Reinnervation aspects of laryngeal transplantation. Eur Arch Otorhinolaryngol. 1998;255(10):515–20.

52. Kluyskens P, Ringoir S. Follow-up of a human larynx transplantation. Laryngoscope. 1970 Aug;80(8):1244–50.

53. Strome M, Stein J, Esclamado R, Hicks D, Lorenz RR, Braun W, Yetman R, Eliachar I, Mayes J. Laryngeal transplantation and 40-month follow-up. N Engl J Med. 2001 May 31;344(22):1676–9.

54. Monaco AP. Transplantation of the larynx--a case report that speaks for itself. N Engl J Med. 2001 May 31;344(22):1712–4.

55. Tintinago L, White A, Lopez B, Casas C. Trasplante de laringe y tráquea superior como opción terapéutica en trauma laringotraqueal irreparable. Acta Otorrinolaringol Cir Cabeza Cuello. 2002;30 Suppl 4:102–109.

56. Farwell DG, Birchall MA, Macchiarini P, Luu QC, de Mattos AM, Gallay BJ, Perez RV, Grow MP, Ramsamooj R, Salgado MD, Brodie HA, Belafsky PC. Laryngotracheal transplantation: technical modifications and functional outcomes. Laryngoscope. 2013 Oct;123(10):2502–8.

57. Jo HK, Park JW1, Hwang JH1, Kim KS1, Lee SY1, Shin JH2. Risk acceptance and expectations of laryngeal allotransplantation. Arch Plast Surg. 2014 Sep;41(5):505–12.

58. Rose KG, Sesterhenn K, Wustrow F. Tracheal allotransplantation in man. Lancet. 1979 Feb 24;1(8113):433.

59. Levashov YuN, Yablonsky PK, Cherny SM, Orlov SV, Shafirovsky BB, Kuznetzov IM. One-stage allotransplantation of thoracic segment of the trachea in a patient with idiopathic fibrosing mediastinitis and marked tracheal stenosis. Eur J Cardiothorac Surg. 1993;7(7):383–6.

60. Herberhold C, Stein M, von Falkenhausen M. Long-term results of homograft reconstruction of the trachea in childhood. Laryngorhinootologie. 1999 Dec;78(12):692–6.

61. Jacobs JP, Quintessenza JA, Andrews T, Burke RP, Spektor Z, Delius RE, Smith RJ, Elliott MJ, Herberhold C. Tracheal allograft reconstruction: the total North American and worldwide pediatric experiences. Ann Thorac Surg. 1999 Sep;68(3):1043–51; discussion 1052.

62. Klepetko W, Marta GM, Wisser W, Melis E, Kocher A, Seebacher G, Aigner C, Mazhar S. Heterotopic tracheal transplantation with omentum wrapping in the abdominal position preserves functional and structural integrity of a human tracheal allograft. J Thorac Cardiovasc Surg. 2004 Mar;127(3):862–7.

63. Delaere PR, Vranckx JJ, Meulemans J, Vander Poorten V, Segers K, Van Raemdonck D, De Leyn P, Decaluwé H, Dooms C, Verleden G. Learning curve in tracheal allotransplantation. Am J Transplant. 2012 Sep;12(9):2538–45.

64. Tintinago LF, Herrera DA, Medina E, Patiño JH, Cano F, Restrepo CS. Ultrasonographic evaluation of a vascularized tracheal transplantation. J Ultrasound Med. 2005 Aug;24(8):1145–9.

65. Birchall M. Tongue transplantation. Lancet. 2004 May 22;363(9422):1663.

66. Chi JJ, Haughey BH. Tongue Transplantation. Curr Otorhinolaryngol Rep 2014;2:178–183.

67. Dorafshar AH, Bojovic B, Christy MR, Borsuk DE, Iliff NT, Brown EN, Shaffer CK, Kelley TN, Kukuruga DL, Barth RN, Bartlett ST, Rodriguez ED. Total face, double jaw, and tongue transplantation: an evolutionary concept. Plast Reconstr Surg. 2013 Feb;131(2):241–51.

68. The world’s first composite transplantation of neck organs carried out by a Polish team. [Internet] May 2015. Available from: http://losangeles.msz.gov.pl/en/c/MOBILE/news/the_world_s_first_composite_transplantation_of_neck_organs_carried_out_by_a_polish_team_

69. Polish doctors perform rare, extensive throat transplant. [Internet] May 2015. Available from: http://www.nydailynews.com/life-style/health/polish-doctors-perform-rare-throat-transplant-article-1.2209664

70. Levi DM, Tzakis AG, Kato T, Madariaga J, Mittal NK, Nery J, Nishida S, Ruiz P. Transplantation of the abdominal wall. Lancet. 2003 Jun 28;361(9376):2173–6.

71. Cipriani R, Contedini F, Santoli M, Gelati C, Sgarzani R, Cucchetti A, Lauro A, Pinna AD. Abdominal wall transplantation with microsurgical technique. Am J Transplant. 2007 May;7(5):1304–7.

72. Giele H, Bendon C, Reddy S, Ramcharan R, Sinha S, Friend P, Vaidya A. Remote revascularization of abdominal wall transplants using the forearm. Am J Transplant. 2014 Jun;14(6):1410–6.

73. Ravindra KV, Martin AE, Vikraman DS, Brennan TV, Collins BH, Rege AS, Hollenbeck ST, Chinappa-Nagappa L, Eager K, Cousino D, Sudan DL. Use of vascularized posterior rectus sheath allograft in pediatric multivisceral transplantation--report of two cases. Am J Transplant. 2012 Aug;12(8):2242–6.

74. Agarwal S, Dorafshar AH, Harland RC, Millis JM, Gottlieb LJ. Liver and vascularized posterior rectus sheath fascia composite tissue allotransplantation. Am J Transplant. 2010 Dec;10(12):2712–6.

75. Selvaggi G, Levi DM, Cipriani R, Sgarzani R, Pinna AD, Tzakis AG. Abdominal wall transplantation: surgical and immunologic aspects. Transplant Proc. 2009 Mar;41(2):521–2.

76. Tietze A. Ersatz des resecierten unteren radiusendes durch eine grosszehenphalange Vehr Etsch Ges Chir Einunddreissigster Congress 1902;1:77.

77. Lexer E. Joint transplantation and arthroplasty. Surg Gynecol Obstet. 1925;40:782–809.

78. Volkov M. Allotransplantation of joints. J Bone Joint Surg Br. 1970, Feb;52(1):49–53.

79. Doi K, Akino T, Shigetomi M, Muramatsu K, Kawai S. Vascularized bone allografts: review of current concepts. Microsurgery. 1994;15(12):831–41.

80. Hofmann GO, Kirschner MH. Clinical experience in allogeneic vascularized bone and joint allografting. Microsurgery. 2000;20(8):375–83.

81. Diefenbeck M, Wagner F, Kirschner MH, Nerlich A, Mückley T, Hofmann GO. Outcome of allogeneic vascularized knee transplants. Transpl Int. 2007 May;20(5):410–8.

82. Cavadas PC, Thione A, Carballeira A, Blanes M. Bilateral transfemoral lower extremity transplantation: result at 1 year. Am J Transplant. 2013 May;13(5):1343–9.

83. Hu W, Lu J, Zhang L, Wu W, Nie H, Zhu Y, Deng Z, Zhao Y, Sheng W, Chao Q, Qiu X, Yang J, Bai Y. A preliminary report of penile transplantation: part 2. Eur Urol. 2006 Nov;50(5):1115–6; discussion 1116.

84. Hu W, Lu J, Zhang L, Wu W, Nie H, Zhu Y, Deng Z, Zhao Y, Sheng W, Chao Q, Qiu X, Yang J, Bai Y. A preliminary report of penile transplantation. Eur Urol. 2006 Oct;50(4):851–3.

85. BBC News. South Africans perform first ‘successful’ penis transplant. [Internet] March 2015. Available from: http://www.bbc.com/news/health-31876219

86. CNN News. First penis transplant patient’s girlfriend is pregnant, doctor says. [Internet] June 2015. Available from: http://edition.cnn.com/2015/06/12/health/penis-transplant-south-africa-pregnancy/

87. McKay DB, Josephson MA. Pregnancy in recipients of solid organs--effects on mother and child. N Engl J Med. 2006 Mar 23;354(12):1281–93.

88. Wranning CA, Akhi SN, Diaz-Garcia C, Brännström M. Pregnancy after syngeneic uterus transplantation and spontaneous mating in the rat. Hum Reprod. 2011 Mar;26(3):553–8.

89. Díaz-García C, Akhi SN, Wallin A, Pellicer A, Brännström M. First report on fertility after allogeneic uterus transplantation. Acta Obstet Gynecol Scand. 2010 Nov;89(11):1491–4.

90. Erman Akar M, Ozkan O, Aydinuraz B, Dirican K, Cincik M, Mendilcioglu I, Simsek M, Gunseren F, Kocak H, Ciftcioglu A, Gecici O, Ozkan O. Clinical pregnancy after uterus transplantation. Fertil Steril. 2013 Nov;100(5):1358–63.

91. Brännström M, Johannesson L, Bokström H, Kvarnström N, Mölne J, Dahm-Kähler P, Enskog A, Milenkovic M, Ekberg J, Diaz-Garcia C, Gäbel M, Hanafy A, Hagberg H, Olausson M, Nilsson L. Livebirth after uterus transplantation. Lancet. 2015 Feb 14;385(9968):607–16.

92. Jones TR, Humphrey PA, Brennan DC. Transplantation of vascularized allogeneic skeletal muscle for scalp reconstruction in renal transplant patient. Transplant Proc. 1998 Sep;30(6):2746–53.

93. Peacock EE Jr, Madden JW. Human composite flexor tendon allografts. Ann Surg. 1967 Oct;166(4):624-9.

94. Asencio G, Abihaidar G, Leonardi C. Human composite flexor tendon allografts. A report of two cases. J Hand Surg Br. 1996 Feb;21(1):84–8.

95. Gimberteau JC. Ten years follow-up of two cases of vascularized digital flexor system allotransplantation. In Composite tissue allografts (ed. Dubernard JM) Paris: John Libbey Eurotext 2001:41–42.

96. Robertson A, Nutton RW, Keating JF. Current trends in the use of tendon allografts in orthopaedic surgery. J Bone Joint Surg Br. 2006 Aug;88(8):988–92.

97. Albert E. Wien Med Presse. 1885;26:1285

98. Mackinnon SE, Hudson AR. Clinical application of peripheral nerve transplantation. Plast Reconstr Surg. 1992 Oct;90(4):695–9.

99. Mackinnon SE, Doolabh VB, Novak CB, Trulock EP. Clinical outcome following nerve allograft transplantation. Plast Reconstr Surg. 2001 May;107(6):1419–29.

100. Carpenter JP, Tomaszewski JE. Immunosuppression for human saphenous vein allograft bypass surgery: a prospective randomized trial. J Vasc Surg. 1997 Jul;26(1):32–42.

101. O’Bichere A, Shurey S, Sibbons P, Green C, Phillips RK. Experimental model of anorectal transplantation. Br J Surg. 2000 Nov;87(11):1534–9.

102. Galvão FH, Waisberg DR, De Mello Vianna RM, De Castro Galvão R, Seid VE, Andraus W, Chaib E, D’Albuquerque LA. Intestinal transplantation including anorectal segment in the rat. Microsurgery. 2012 Jan;32(1):77–9.

103. Araki J, Mihara M, Narushima M, Iida T, Sato T, Koshima I. Vascularized anal autotransplantation model in rats: preliminary report. Transplant Proc. 2011 Nov;43(9):3552–6.

104. Araki J, Nishizawa Y, Sato T, Naito M, Akita K, Tashiro K, Iida T, Koshima I. Anorectal transplantation in human cadavers: mock anorectal allotransplantation. PLoS One. 2013 Jul 11;8(7):e68977.

105. Malaysia baby gets transplanted arm of her twin sister. Daily News [Internet]. December 2000. Available from: http://www.hurriyetdailynews.com/malaysia-baby-gets-transplanted-arm-of-her-twin-sister.aspx?pageID=438&n=malaysia-baby-gets-transplanted-arm-of-her-twin-sister-2000-06-12

106. Baby given tragic sister’s arm. Daily Mail [Internet]. Available from: http://www.dailymail.co.uk/health/article-5503/Baby-given-tragic-sisters-arm.html 107. Zuker RM, Redett R, Alman B, Coles JG, Timoney N, Ein SH.First successful lower-extremity transplantation: technique and functional result. J Reconstr Microsurg. 2006 May;22(4):239–44.

108. Fattah A, Cypel T, Donner EJ, Wang F, Alman BA, Zuker RM. The first successful lower extremity transplantation: 6-year follow-up and implications for cortical plasticity. Am J Transplant. 2011 Dec;11(12):2762–7.

Štítky
Chirurgie plastická Ortopedie Popáleninová medicína Traumatologie

Článek vyšel v časopise

Acta chirurgiae plasticae

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