Cytomorphology of mature CD5-positive B-cell neoplasms

Česká verze

Authors: D. Starostka; P. Mikula; D. Koláček; K. Chasáková; H. Taliánová; P. Miczková; L. Novosadová
Authors place of work: Oddělení klinické hematologie, Nemocnice s poliklinikou, Havířov
Published in the journal: Transfuze Hematol. dnes,23, 2017, No. 3, p. 117-126.
Category: Souhrnné práce, původní práce, kazuistiky

Summary

Diagnosis of mature CD5-positive B-cell neoplasms is multidisciplinary. The goal of this study was to evaluate the diagnostic significance of cytomorphology in 233 diagnostic specimens of mature CD5-positive B-cell neoplasms. Cytomorphology assessment used light microscopy (Nikon Eclipse Ni). In the sample analysed, we diagnosed: CLL –⁠ both typical and atypical CLL (CLL/PL, pleomorphic CLL); SLL –⁠ small cell type; classical MCL, small cell, pleomorphic, blastoid and MZL-like variant, CD5+ MZL –⁠ small cell type, medium/large lymphocyte type, pleomorphic type and one with villous lymphocytes; CD5+ DLBCL –⁠ centroblastic, immunoblastic, anaplastic variant; unclassified cases –⁠ small cell type, medium/large lymphocyte type, pleomorphic type. In mature CD5-positive B-cell neoplasms, cytomorphology is a basic, rapid and low-cost method with high diagnostic value.

KEY WORDS:
cytomorphology –⁠ CD5 –⁠ B-cell –⁠ lymphoma –⁠ leukaemia

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