PLOS Genetics - Číslo 1/2021

Viewpoints

1009050

The clarifying role of time series data in the population genetics of HIV

Alison F. Feder, Pleuni S. Pennings, Dmitri A. Petrov

Correction

1009348

Correction: Unified inference of missense variant effects and gene constraints in the human genome

Research Article

1008540

MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen

Hannah Weber, Rachel Ruoff, Michael J. Garabedian

1008871

Factors enforcing the species boundary between the human pathogens Cryptococcus neoformans and Cryptococcus deneoformans

Shelby J. Priest, Marco A. Coelho, Verónica Mixão, Shelly Applen Clancey, Yitong Xu, Sheng Sun, Toni Gabaldón, Joseph Heitman

1009113

Impaired tumor immune response in metastatic tumors is a selective pressure for neutral evolution in CRC cases

Shotaro Sakimura, Satoshi Nagayama, Mitsuko Fukunaga, Qingjiang Hu, Akihiro Kitagawa, Yuta Kobayashi, Takanori Hasegawa, Miwa Noda, Yuta Kouyama, Dai Shimizu, Tomoko Saito, Atsushi Niida, Yusuke Tsuruda, Hajime Otsu, Yoshihiro Matsumoto, Hiroki Uchida, Takaaki Masuda, Keishi Sugimachi, Shin Sasaki, Kazutaka Yamada, Kazuki Takahashi, Hideki Innan, Yutaka Suzuki, Hiromi Nakamura, Yasushi Totoki, Shinichi Mizuno, Masanobu Ohshima, Tatsuhiro Shibata, Koshi Mimori

1009210

Population structure of indigenous inhabitants of Arabia

Katsuhiko Mineta, Kosuke Goto, Takashi Gojobori, Fowzan S. Alkuraya

1009224

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

Denis A. Baird, Jimmy Z. Liu, Jie Zheng, Solveig K. Sieberts, Thanneer Perumal, Benjamin Elsworth, Tom G. Richardson, Chia-Yen Chen, Minerva M. Carrasquillo, Mariet Allen, Joseph S. Reddy, Philip L. De Jager, Nilufer Ertekin-Taner, Lara M. Mangravite, Ben Logsdon, Karol Estrada, Philip C. Haycock, Gibran Hemani, Heiko Runz, George Davey Smith, Tom R. Gaunt,

1009236

Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect

Julia Böck, Einar Krogsaeter, Marcel Passon, Yu-Kai Chao, Sapna Sharma, Harald Grallert, Annette Peters, Christian Grimm

1009253

Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus

Xavier Grau-Bové, Eric Lucas, Dimitra Pipini, Emily Rippon, Arjèn E. van ‘t Hof, Edi Constant, Samuel Dadzie, Alexander Egyir-Yawson, John Essandoh, Joseph Chabi, Luc Djogbénou, Nicholas J. Harding, Alistair Miles, Dominic Kwiatkowski, Martin J. Donnelly, David Weetman,

1009284

A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant

Pierre-Emmanuel Morange, Franck Peiretti, Lenaick Gourhant, Carole Proust, Omar Soukarieh, Anne-Sophie Pulcrano-Nicolas, Ganapathi-Varma Saripella, Luca Stefanucci, Romaric Lacroix, Manal Ibrahim-Kosta, Catherine A. Lemarié, Mattia Frontini, Marie-Christine Alessi, David-Alexandre Trégouët, Francis Couturaud

1009285

Genome-scale CRISPR screening for modifiers of cellular LDL uptake

Brian T. Emmer, Emily J. Sherman, Paul J. Lascuna, Sarah E. Graham, Cristen J. Willer, David Ginsburg

1009287

Htt is a repressor of Abl activity required for APP-induced axonal growth

Claire Marquilly, Germain U. Busto, Brittany S. Leger, Ana Boulanger, Edward Giniger, James A. Walker, Lee G. Fradkin, Jean-Maurice Dura

1009295

Temperature regulates synaptic subcellular specificity mediated by inhibitory glutamate signaling

Mengqing Wang, Daniel Witvliet, Mengting Wu, Lijun Kang, Zhiyong Shao

1009300

Epithelial cell-turnover ensures robust coordination of tissue growth in Drosophila ribosomal protein mutants

Nanami Akai, Shizue Ohsawa, Yukari Sando, Tatsushi Igaki

1009304

Kinetochore-independent mechanisms of sister chromosome separation

Hannah Vicars, Travis Karg, Brandt Warecki, Ian Bast, William Sullivan

1009310

Consequences of adaptation of TAL effectors on host susceptibility to Xanthomonas

Doron Teper, Nian Wang

1009321

Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance

Andrew Hammond, Xenia Karlsson, Ioanna Morianou, Kyros Kyrou, Andrea Beaghton, Matthew Gribble, Nace Kranjc, Roberto Galizi, Austin Burt, Andrea Crisanti, Tony Nolan

1009325

Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity

Lewin Small, Lars R. Ingerslev, Eleonora Manitta, Rhianna C. Laker, Ann N. Hansen, Brendan Deeney, Alain Carrié, Philippe Couvert, Romain Barrès

PLOS Genetics

2021 Číslo 1

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