Angiotropic Lymphoma (Intravascular Lymphomatosis): Description of TwoCases

Authors: Z. Kinkor 1;  I. Svitáková 1;  Š. Hadravská 2;  V. Hejda 2;  M. Matějovič 3
Authors‘ workplace: Odd. patologie, FN Na Bulovce, Praha 2Šiklův ústav patologie, LF UK, Plzeň 3I. interní klinika, LF UK, Plzeň 1
Published in: Čes.-slov. Patol., , 2003, No. 1, p. 21-25


Described are two cases of angiotropic lymphoma where eventually autopsy elucidated nonspecificneurologic symptoms. One patient suffering ambiguous encephalitic syndrome died threemonths later, the second one passed away after an unusually long three -year period of progressivedementia and cumulative motoric dysfunction. The autopsy disclosed pure intravascular malignantlymphoid aggregates (LCA, CD 20, Bcl 2-positive) in the brain and kidney of both patients.In the patients with the longer disease period, a dissemination to lung was also found. Definitivediagnosis was issued as a B cell type of angiotropic lymphoma. Skin, lymph nodes, spleen, andbone marrow were not affected in any case. The clinical differential diagnosis algorithm did notinvolve this rare etiology in these particular uncommon neurologic cases and even brain biopsyperformed in both women did not recognize the substantiality of the disease.

Key words:
brain -B cell lymphoma - intravascular lymphomatosis - angiotropic lymphoma - malignantangioendotheliomatosis

Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP.

Anatomical pathology Forensic medical examiner Toxicology

Article was published in

Czecho-Slovak Pathology

2003 Issue 1

Most read in this issue

This topic is also in:

Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account