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Arthritis

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Reduction of Enthesitis in Patients with Psoriatic Arthritis Taking Tofacitinib

24. 11. 2023 Source: Arthritis

Inflammation in the area where a tendon, ligament, or joint capsule attaches to the bone occurs in 35–50% of patients with psoriatic arthritis (PsA). Its presence is associated with higher activity of PsA, and its intensity correlates with the degree of joint damage. Patients with enthesitis are generally in worse functional status and report greater fatigue, pain, and decreased productivity. How can treatment with tofacitinib affect this important domain of PsA?

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Reduction of Inflammation in Vertebral Bodies and Posterolateral Structures of the Spine in Patients with Ankylosing Spondylitis Treated with Tofacitinib

A post hoc analysis of a phase II study with tofacitinib in patients with active ankylosing…
23. 11. 2023 Source: Arthritis
rheumatoid arthritis  ilustrace

Discontinuation of Methotrexate After Initiation of Tofacitinib in the Treatment of Rheumatoid Arthritis

New real-world data show that in patients with rheumatoid arthritis (RA) who started treatment with…
27. 7. 2022 Source: Arthritis

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artritida cislo 1

EULAR 2023: How does tofacitinib affect cardiovascular risk in rheumatoid arthritis?

At this year's European League Against Rheumatism (EULAR) congress, held at the turn of May…
23. 8. 2023 Source: Arthritis
artritida cislo 2

EULAR 2023: What Do CRP Levels Reveal About the Efficacy and Safety of Tofacitinib in Patients with Ankylosing Spondylitis?

What is the impact of baseline C-reactive protein (CRP) levels on the efficacy and safety of…
22. 8. 2023 Source: Arthritis
artritida2023

Results of a 10-year follow-up on the safety and efficacy of etanercept treatment in patients with juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is defined as persistent arthritis of unknown etiology…
10. 7. 2023 Source: Arthritis
lung diseases rheumatism

Comparison of the Risk of Interstitial Lung Disease in Patients with RA with Biological and Targeted Disease-Modifying Antirheumatic Therapy

The authors of a newly published study sought to answer whether the risk of developing…
8. 6. 2023 Source: Arthritis
artritida66

Fresh data from real clinical practice on targeted treatment of RA with etanercept: Should therapy be changed after 12 weeks due to insufficient response?

A recently published German study investigated, among other things, what percentage of…
24. 11. 2022 Source: Arthritis
žilní tromboembolie

Incidence of CV Events, Malignancies, and Venous Thromboembolism in Patients with RA According to Baseline CV Risk and Administered Treatment

An international team of experts evaluated the impact of cardiovascular (CV) risk on the…
27. 7. 2022 Source: Arthritis
etanerceptu v terapii artritid

Efficacy and Safety of Etanercept in the Therapy of Arthritis

A review by experts from Genoa, Italy, focused on the available knowledge regarding the…
7. 6. 2022 Source: Arthritis
aktivní psoriatickou artritidou

Safety and Efficacy of Long-term Tofacitinib Therapy in Patients with Active Psoriatic Arthritis –⁠ Interim Results of the OPAL Balance Study

Tofacitinib is a potent selective inhibitor of the Janus kinase (JAK) family indicated for the…
30. 5. 2022 Source: Arthritis
cardiovascular disease arthritis

Cardiovascular Safety of Tofacitinib in Real-World Clinical Practice –⁠ Results of the STAR-RA Study

Recent results from the ORAL Surveillance clinical trial have raised concerns about the…
29. 5. 2022 Source: Arthritis
Treatment of Knee Pain and Arthritis

Long-term Efficacy of Targeted Therapy for Axial Spondyloarthritis

How does etanercept fare in the long-term treatment of early axial spondyloarthritis (axSpA)?…
19. 4. 2022 Source: Arthritis
rheumatoid arthritic disease

Continuation of Treatment with Tofacitinib in Rheumatoid Arthritis –⁠ Real-World Clinical Practice Data

The oral Janus kinase inhibitor tofacitinib has been extensively tested in patients with…
29. 3. 2022 Source: Arthritis
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Is it beneficial to combine etanercept and methotrexate in the treatment of psoriatic arthritis?

The study presented below by Canadian, American, and British authors focused on comparing the…
28. 3. 2022 Source: Arthritis
revmatoidni artritida

Cell-Based Implant as a Stable System for Biological Therapy Delivery

A team of scientists from Washington University in St. Louis focused on the possibility of…
19. 11. 2021 Source: Arthritis
revmaticke ruce

Comparable Long-term Safety of Tofacitinib and Biologics in RA Treatment –⁠ Data from a US Registry

An analysis of the long-term safety profile of tofacitinib in real clinical practice was…
18. 11. 2021 Source: Arthritis
zapesti_bolest

Effect of Etanercept on Structural Changes in the Sacroiliac Joint in Patients with Early Axial Spondyloarthritis

Currently, there is limited evidence regarding the effect of tumor necrosis factor inhibitors…
14. 8. 2021 Source: Arthritis

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