Retroperitoneal Schwannoma with Features ofGastrointestinal Schwannoma. A Case Report

Authors: M. Zámečník 1;  F. Koyš 2
Authors‘ workplace: Šikl´s Department of Pathology, Faculty Hospital, Charles University, Pilsen, Czech Republic2Department of Pathology, General Hospital, Považská Bystrica, Slovak Republic 1
Published in: Čes.-slov. Patol., , 2003, No. 1, p. 36-38


A case of retroperitoneal schwannoma with histological features of gastrointestinal (GI) schwannomaoccurring in a 67-year-old woman is reported. The tumor was composed of spindle cells withfocal pseudoatypism and it showed several features typical of gastrointestinal-type schwannomasuch as lymphocytic infiltration, peripheral cuff of lymphocytes, lack of Antoni A pattern, andabsence of thick walled vessels. Immunohistochemically, the tumor showed diffuse reactivity forS100 protein and glial fibrillary acidic protein. The authors discuss a phenotypical similarity ofthe lesion with GI schwannoma as well as the possible existence of GI-type schwannoma outsidethe tubal GI tract.

Key words:
gastrointestinal tract – gastric schwannoma – schwannoma – retroperitoneum – softtissue

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Czecho-Slovak Pathology

2003 Issue 1

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