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PLOS Genetics - Číslo 12/2020

Perspective

1009177
Precision medicine in cats—The right biomedical model may not be the mouse!

Leslie A. Lyons


Research Article

1008603
Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence

Tina Wagner, Lara Pérez-Martínez, René Schellhaas, Marta Barrientos-Moreno, Merve Öztürk, Félix Prado, Falk Butter, Brian Luke

1008671
PEA15 loss of function and defective cerebral development in the domestic cat

Emily C. Graff, J. Nicholas Cochran, Christopher B. Kaelin, Kenneth Day, Heather L. Gray-Edwards, Rie Watanabe, Jey W. Koehler, Rebecca A. Falgoust, Jeremy W. Prokop, Richard M. Myers, Nancy R. Cox, Gregory S. Barsh, Douglas R. Martin,

1008948
Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans

Vincent Gaggioli, Manuela R. Kieninger, Anna Klucnika, Richard Butler, Philip Zegerman

1008960
Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma

Pilar Delgado, Ángel F. Álvarez-Prado, Ester Marina-Zárate, Isora V. Sernandez, Sonia M. Mur, Jorge de la Barrera, Fátima Sanchez-Cabo, Marta Cañamero, Antonio de Molina, Laura Belver, Virginia G. de Yébenes, Almudena R. Ramiro

1009170
Culture-free genome-wide locus sequence typing (GLST) provides new perspectives on Trypanosoma cruzi dispersal and infection complexity

Philipp Schwabl, Jalil Maiguashca Sánchez, Jaime A. Costales, Sofía Ocaña-Mayorga, Maikell Segovia, Hernán J. Carrasco, Carolina Hernández, Juan David Ramírez, Michael D. Lewis, Mario J. Grijalva, Martin S. Llewellyn

1009191
Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies

Robin N. Beaumont, Sarah J. Kotecha, Andrew R. Wood, Bridget A. Knight, Sylvain Sebert, Mark I. McCarthy, Andrew T. Hattersley, Marjo-Riitta Jarvelin, Nicholas J. Timpson, Rachel M. Freathy, Sailesh Kotecha

1009218
A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between Type 2 Diabetes and Prostate Cancer

Debashree Ray, Nilanjan Chatterjee

1009228
Exploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo

Jessica K. Sawyer, Zahra Kabiri, Ruth A. Montague, Scott R. Allen, Rebeccah Stewart, Sarah V. Paramore, Erez Cohen, Hamed Zaribafzadeh, Christopher M. Counter, Donald T. Fox

1009245
bsAS, an antisense long non-coding RNA, essential for correct wing development through regulation of blistered/DSRF isoform usage

Sílvia Pérez-Lluch, Cecilia C. Klein, Alessandra Breschi, Marina Ruiz-Romero, Amaya Abad, Emilio Palumbo, Lyazzat Bekish, Carme Arnan, Roderic Guigó

1009249
Lotus japonicus karrikin receptors display divergent ligand-binding specificities and organ-dependent redundancy

Samy Carbonnel, Salar Torabi, Maximilian Griesmann, Elias Bleek, Yuhong Tang, Stefan Buchka, Veronica Basso, Mitsuru Shindo, François-Didier Boyer, Trevor L. Wang, Michael Udvardi, Mark T. Waters, Caroline Gutjahr

1009256
Super-resolution visualization of distinct stalled and broken replication fork structures

Donna R. Whelan, Wei Ting C. Lee, Frances Marks, Yu Tina Kong, Yandong Yin, Eli Rothenberg

1009259
Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration

Passley Hargrove-Grimes, Anupam K. Mondal, Jessica Gumerson, Jacob Nellissery, Angel M. Aponte, Linn Gieser, Haohua Qian, Robert N. Fariss, Juan S. Bonifacino, Tiansen Li, Anand Swaroop

1009270
Physiological and genetic convergence supports hypoxia resistance in high-altitude songbirds

Ying Xiong, Liqing Fan, Yan Hao, Yalin Cheng, Yongbin Chang, Jing Wang, Haiyan Lin, Gang Song, Yanhua Qu, Fumin Lei


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