Diabetes mellitus – are there possibilities for prevention?


Authors: prof. MUDr. Pavel Weber, CSc. 1;  MUDr. Hana Meluzínová 1;  MUDr. František Németh, Ph.D. 2;  MUDr. Dana Weberová 1;  MUDr. Katarína Bielaková 1
Authors‘ workplace: Klinika interní, geriatrie a praktického lékařství LF MU a FN Brno 1;  Geriatrická klinika, FN L. Pasteura, Prešov 2
Published in: Geriatrie a Gerontologie 2013, 2, č. 4: 223-226
Category: Review Article

Overview

Diabetes is a chronic disease – or rather a heterogeneous syndrome – which can be both generally and in old age characterized by hyperglycaemia, lack of insulin action, and a tendency to develop late-onset complications (damage to blood vessels and tissues). It is a manifestation of impaired glucose homeostasis and intermediary metabolism of virtually all levels of the organism. Changes in the internal environment are a hyperglycaemic state induced by both intra- and extracellular factors. As for diabetics, the disease will affect them for the rest of their lives, requiring good compliance and strict adherence to treatment. When poor compensation occurs, serious complications gradually develop, such as visual impairment possibly leading to blindness, kidney failure, amputations of the lower limbs and cardio- and cerebrovascular complications.

Keywords:
diabetes mellitus – ethiopathogenesis – epidemiology – late complications – future perspective – prevention


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