#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Risk factors for venous thrombosis


Authors: M. Matýšková;  M. Šlechtová
Authors‘ workplace: Oddělení klinické hematologie FN Brno
Published in: Geriatrie a Gerontologie 2013, 2, č. 4: 201-205
Category: Review Article

Overview

Pathogenesis of thrombosis is based on multiple factors. In past years many interacting factors were described, both inherited and environmental. Surveying these should be indicated only in cases where knowledge of the defect can influence patient’s treatment or prophylaxis. We should examine only factors in which there is a proven relation to clinical picture. We should always take family and personal history into account while interpreting the results.

Keywords:
thrombophilia – venous thromboembolism – laboratory examination


Sources

1. White RH: The epidemiology of venous thromboembolism. Circulation 2003; 107: I-4–I-8.)

2. Cushman M: Epidemiology and risk factors for venous thrombosis. Semin Hematol 2007; 44(2): 62–69.

3. Agnelli G, Prandoni P, Santamaria MG et al.: Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis. N Engl J Med 2001; 345:165–169.

4. http://www.bpac.org.nz/resources/bt/2011/03_thrombophilia.asp

5. Middeldorp S: Is thrombophilia testing useful? ASH Education Book 2011; 1:150–155.

6. Walker ID, Greaves M: Preston FE on behalf of the Haemostasis and Thrombosis Task Force British Committee for Standards in Hematology. Investigation and management of heritable thrombophilia. Br J Haematol 2001; 114: 512–528.

7. NICE guidance CG92 Venous thromboembolism – reducing the risk Issude: January 2010. http://guidance.nice.org.uk/CG92

8. Rosendaal FR: Risk Factors for venous thrombotic Disease. Thromb Haemost 1999; 82: 610–619.

9. Matýšková M, Paseka J, Vorlová Z et al.: Prevalence of factor V Leiden mutation in healthy women. In: Scharrer I, Schramm W: 29. Hämophilie - Symposion Hamburg 1998, Springer 1999, 309–311.

10. Rossi E. Za T, Ciminello A et al.: The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia. Thromb Haemost 2008; 15 (6): 1030–1034.

11. Ho WK, Hankey GJ, Quinlan DJ, Eikelboom JW: Risk of recurrent venous thromboembolism in patients with common thrombophilia. Arch Intern Med 2006; 166: 729–736.

12. Pomp ER, Lenselink, AM, Rosendaal, FR, Doggen CJM: Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study. J Thromb Haemost 2008; 6: 632–637.

13. Dulíček P, Malý J, Kalousek I et al.: Výskyt venózního tromboembolizmu u žen s Leidenskou mutací v souvislosti s graviditou a šestinedělím. Čes Gynekol 2005; 70 (2): 133–138.

14. Robertson L, Wu O, Langhorne P et al.: For the TREATS study: Thrombophilia in pregnancy: a systematic review. Br J Haematol 2005; 132: 171–196.

15. Haverkate F: Familial dysfibrinogenemia and thrombophilia. Thromb Haemost 1995; 73(1): 151–61.

16. Kamphuisen PW, Eikenboom JCJ, Bertina RM: Elevated Factor VIII levels and the risk of thrombosis. Arterioscler Thromb Vasc Biol 2001; 21: 731–738.

17. Kyrle PA, Minar E, Hirschlm M et al.: High plasma levels of factor VIII and the risk of recurrent venous thromboembolism. N Engl J Med 2000; 343: 457–462.

18. Legnani C, Cosmi B, Cini M et al.: High plasma levels of factor VIII and risk of recurrence of venous thromboembolism. Br J Haemeatol 2004; 124: 504–510.

19. Ariëns RA: Elevated fibrinogen causes thrombosis. Blood 2011; 117(18): 4687–4688.

20. Hyánek J et al.: Hyperhomocysteinemia – unrecognized and neglected. Clin Biochem Metab 2009; 2: 83–92.

21. Kottke-Marchant K, Green R, Jacobsen DW et al.: High plasma homocystein: a risk factor for arterial and venous thrombosis in patients with normal coagulation profiles. Clin. Appl. Thrombosis/Hemostasis 1997; 3(4): 239–244.

22. Buliková A, Penka M: Antifosfolipidový syndrome – diagnostika a léčba. Vnitř Lék 2005; 51(7&8): 809–817.

23. Tondeur S, Boutruche S, Biron-Andréani C, Schved JF: Prevalence of the Jak2 V617F mutation associated with splanchnic vein thrombosis. A 10-year retrospective study. Thromb Haemost 2009; 101: 787–789.

24. Ageno W, Squizzato A, Ambrosini F et al.: Thrombosis prophylaxis in medical patients: a retrospective review of clinical practice patterns. Haematologica 2002; 87:746–750.

25. Lee AYY: Thrombosis in cancer: An update on prevention, treatment, and survival benefits of anticoagulants. ASH Education Book 2010; 1: 144–149.

26. Horsted F, West J, Grainge J: Risk of venous thromboembolism in patients with cancer: A systematic review and meta-analysis. PLoS Med 2012; 9(7): http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001275

27. Anderson FA Jr, Spencer FA: Risk Factors for venous thromboembolism. Circulation 2003; 107: I-9–I-16.

28. Rosendaal FR: Venous Thrombosis: The Role of Genes, Environment, and Behavior. ASH Education Book 2005; 1: 1–12.

29. Blanco-Molina Á, Trujillo-Santos J, Tirado R et al.: Venous thromboembolism in women using hormonal contraceptives. Findings from the RIETE Registry. Thromb Haemost 2009; 15 (3): 478–482.

30. van Vlijmen EF, Brouwer JL, Veeger NJ et al.: Oral contraceptives and the absolute risk of venous thromboembolism in women with single or multiple thrombophilic defects: results from a retrospective family cohort study. Arch Intern Med 2007; 167: 282–289.

31. Jick H, Slone D, Westerholm B et al.: Venous thromboembolic disease and AB0 blood group type. A cooperative study. Lancet 1969; 1: 539–542.

32. Matýšková M, Zavřelová J, Pejchalová A et al.: Krevní skupiny AB0 a faktor V Leiden. Čas lék čes 2002; 141 (5): 146–151.

33. Abdollahi M, Cushman M, Rosendaal FR: Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use. Thromb Haemost 2003; 89: 493–498.

34. Oger E, Lacut K, Le Gal G: Hyperhomocysteinemia and low B vitamin levels are independently associated with venous thromboembolism: results from the EDITH study: a hospital-based case–control study. J Thromb Haemost 2006; 4: 793–799.

35. Hron G, Lombardi R, Eichinger S et al.: Low vitamin B6 levels and the risk of recurrent venous thromboembolism. Haematologica 2007; 92(9): 1250–1253.

36. Zakai AA, Wright J, Cushman M: Risk factors for venous thrombosis in medical inpatients: validation of a thrombosis risk score. J Thromb Haemost 2004; 2:2156–2161.

37. White RH, Zhou H, Gage BF: Effect of age on the incidence of venous thromboembolism after major surgery. J Thromb Haemost 2004; 2: 1327–1333.

38. Cannegieter SC, Doggen CJM, van Houwelingen HC, Rosen-daal FR: Travel-related venous thrombosis: results from a large population-based case control study (MEGA Study). PLoS Med 2006; 3. http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0030307

39. Steffen LM: Greater fish, fruit, and vegetable Intakes are related to lower Incidence of venous thromboembolism. The longitudinal investigation of thromboembolism etiology. Circulation 2007; 115: 188–195.

40. Baglin T, Gray E, Greaves M et al.: Clinical guidelines for testing for heritable thrombophilia. Br J Haematol 2010; 149: 209–220.

41. Dalen JE: Should patients with venous thromboembolism be screened for thrombophilia? Am J Med 2008; 121: 458-463.

42. Coppens M, Reijnders JH, Middeldorp S et al.: Testing for inherited thrombophilia does not reduce the recurrence of venous thrombosis.J Thromb Haemost 2008; 6: 1474–1477.

43. Cosmi B: Value of D-dimer testing to decide duration of anticoagulation after deep vein thrombosis: yes. J Thromb Haemost 2006; 4: 2527–2529.

44. Bruinstroop E, Klok FA, van de Ree MA et al.: Elevated D-dimer levels predict recurrence in patients with idiopathic venous thromboembolism: a meta-analysis. J Thromb Haemost 2009; 7:611–618.

45. Lijfering WM, Brouwer JLP, Veeger NJGM et al.: Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives. Blood 2009; 113: 5314–5322.

46. Anard-Michelot H, Siguret V, Gouin-Thibault I et al.: Screening for thrombophilic abnormalities in very elderly patients. Ann Biol Clin (Paris) 2010; 68 (6): 643–648.

47. Middeldorp S: Evidence-based approach to thrombophilia testing.J Thromb Thrombolysis 2011; 31: 275–281.

Labels
Geriatrics General practitioner for adults Orthopaedic prosthetics
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#