Idiopathic thrombocytopenic purpura

Authors: L. Raida;  A. Hluší;  J. Procházková;  J. Juráňová
Authors‘ workplace: Lékařská fakulta Univerzity Palackého, Olomouc ;  Fakultní nemocnice Olomouc ;  Hemato-onkologická klinika ;  Přednosta: Prof. MUDr. Karel Indrák, DrSc.
Published in: Prakt. Lék. 2008; 88(12): 690-694
Category: Reviews


Idiopathic thrombocytopenic purpura (ITP) is a disease commonly seen by the haematologist. The incidence of ITP is 6 patients per 100 000 people a year. Children, usually suffering from the acute form of ITP, represent approximately half of these patients. On the other hand, the majority of adult patients require repeated therapeutic intervention because of recurrent chronic ITP associated with severe thrombocytopenia. It normally affects adults between 50 and 60 years of age. Many elderly patients have a significant comorbidity and their health status can be made worse with haematological treatment. Patients with active ITP accompanied with significant thrombocytopenia may often have to be referred back to various specialists to modify some diagnostic and therapeutic approaches.

Key words:
idiopathic thrombocytopenic purpura, corticosteroids, immunoglobulins, anti-D globulin, splenectomy, rituximab.


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