Biologic treatment for rheumatoid arthritis

Authors: K. Trnavský
Authors‘ workplace: Arthrocentrum, Praha
Published in: Prakt. Lék. 2008; 88(12): 725-727
Category: Of different specialties


Biologic treatment – the administration of monoclonal antibodies against cytokines and immunocompetent cells that participate in the rheumatoid inflammation – can be considered a major advance in the therapy of rheumatoid arthritis. The main problem with this form of therapy is the cost factor. Therefore, indications for biological therapy, approaches in case of treatment failure and the duration of administration are still under discussion. Adverse reactions are also not negligible – particularly infections including the activation of tuberculosis.

Key words:
rheumatoid arthritis, biologic treatment.


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