Pulmonary tuberculosis in HIV positive infant – first case in the Czech Republic


Authors: M. Tomášková ;  P. Kabíček ;  K. Křepela ;  H. Houšťková
Authors‘ workplace: Pediatrická klinika IPVZ, 1. LF UK a Thomayerova nemocnice, Praha, přednostka doc. MUDr. H. Houšťková, CSc.
Published in: Čes-slov Pediat 2016; 71 (7-8): 351-353.
Category: Tuberculosis

Overview

This case report presents a rare pulmonary tuberculosis in premature infant with congenital HIV infection, both transmitted from infant’s mother. To the best of our knowledge this is the first such a combination of infections described in the Czech Republic in infants

Key words:
congenital HIV infection, pulmonary tuberculosis, antituberculotics, antiretroviral treatment


Sources

1. Venturini E, Turkova A, Chiappini E, et al. Tuberculosis and HIV co-infection in children. BMC Infect Dis 2014; 14 (Suppl 1): S5.

2. Pillay T, Khan M, Moodley J, et al. Perinatal tuberculosis and HIV-1: considerations for resource-limited settings. Lancet Infect Dis 2004 March; 4: 155–165.

3. Schaaf HS, Thee S, van der Laan L, et al. Adverse effects of oral second-line antituberculosis drugs in children. Expert Opin Drug Saf 2016 Oct; 15 (10).

4. Regazzi M, Carvalho AC, Villani P, Matteelli A. Treatment optimization in patients co-infected with HIV and Mycobacterium tuberculosis infections: focus on drug-drug interactions with rifamycins. Clin Pharmacokinet 2014 Jun; 53 (6): 489–507.

5. Maartens G, Decloedt E, Cohen K. Effectiveness and safety of antiretrovirals with rifampicin: crucial issues for high-burden countries. Antivir Ther 2009; 14 (8): 1039–1043.

6. van Oosterhout JJ, Kumwenda JJ, Beadsworth M, et al. Nevirapine-based antiretroviral therapy started early in the course of tuberculosis treatment in adult Malawians. Antivir Ther 2007; 12 (4): 515–521.

Labels
Neonatology Paediatrics General practitioner for children and adolescents
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