Vaginal combined contraception NuvaRing in the clinical practice in the Czech Republic

Authors: T. Fait
Authors‘ workplace: Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc.
Published in: Ceska Gynekol 2009; 74(4): 286-291
Category: Original Article


The aim of this non-interventional, non-comparative, prospective, multicentric study was to evaluate use of vaginal combined contraception NuvaRing in the clinical practice in the Czech Republic.

Non-interventional, non-comparative, prospective, multicentric study.

Department of obstetrics and gynecology, General Faculty Hospital Prague, 1st Faculty of Medicine, Charles University Prague.

The cohort of 2134 new users of NuvaRing was followed for 6 months. Questionnaire was filled in by the physician (gynaecologist) three times during the study – before the start of NuvaRing use (baseline), after 3 months and after 6 months of the ring use.

The average age of women in study was 29,5 years, 68,2% was from 21 to 35 years old. Insertion and removal of the ring were evaluated as easy in 95% of women in the end of the study. Irregular bleeding was mentioned only in 19,7% of women during first 3 cycles and 7,8% during last 3 cycles, mostly (90%) as spotting. Menstrual bleeding was shorter in 62,8% of women in the end of the study compared with the baseline. Dysmenorea decreased by 34,9% and PMS by 28,8% in the last evaluated cycle compared with the baseline. No feeling or only exceptional feeling the of the ring in the vagina was reported in 87% of women and in 77,9% of their sexual partners during the last 3 cycles. The main two reasons why women like NuvaRing was no need to remember anything (57,5%) and easy use (34%). The main reasons why women dislike the ring were feeling of the ring in the vagina in 2,9%, disturbing of sexual intercourse in 2,4% and irregular bleeding in 2%. (90% answered, that they like NuvaRing.)

After six months of use 89% of women was satisfied or highly satisfied with the vaginal ring and 91% of the users was decided to recommend this contraception method to other women.

Key words:
hormonal contraception, vaginal combined contraception, compliance, vaginal bleeding, dysmenorea, premenstrual syndrome.


1. Ahrendt, HJ., Nisand, I., Bastianelli, C., et al. Efficacy, acceptability and tolerability o the combined contraceptive ring, NuvaRing, compared with an oral contraceptive containing 30 mg of ethinylestradiol and 3 mg of drospirenone. Contraception, 2006, 74, 6, p.451-457.

2. Bjarnadottir, RI., Tuppurainen, M., Killick, SR. Comparison of cycle control with combined contraceptive vaginal ring and oral levonorgestrel/ethinylestradiol. Am J Obstet Gynecol, 2002, 186, 3, p. 389-395.

3. Dieben, TO., Roumen, FJ., Apter, D., et al. Efficacy, cycle control and user acceptability of a novel combined contraceptive vaginal ring. Obstet Gynecol, 2002, 100, 3, p. 585-593.

4. Fait, T., Sulova, L. Jenicek, J., Uzel, R. The wide acces to contraception is the best way to downregulation of abortion rate. Eur J Contraception Reprod Health Care, 2008, 13, Suppl 2, p. 54.

5. Lete, I., Doval, JL., Pérez-Campos, E., et al. Self-described impact of noncompliance among users of combined hormonal contraceptive method. Contraception, 2008, 77, 4, p. 276-282.

6. Miller, L., Verhoeven, CH., Hout, J. Extended regimens of the contraceptive vaginal ring. Obstet Gynecol, 2005, 106, 3, p. 473-482.

7. Novak, A., de la Loge, C., Abetz, L., van der Meuen, EA. The combined contraceptive vaginal ring, NuvaRing: an international study of user acceptability. Contraception, 2003, 67, 3, p. 187-194.

8. Oddson, K., Leifels-Fischer, B., Wiel –Masson, D., et al. Superior cycle kontrol with a contraceptive vaginal ring compared with an oral contraceptive containing 30Ķg ethinylestradiol and 150Ķg levonorgestrel: a randomized trial. Hum Reprod, 2005, 20, 2, p. 557-562.

9. Roumen, FJ., Apter, D., Mulders, TM., et al. Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinylestradiol. Hum Reprod, 2001, 16, 3, p. 469-475.

10. Timmer, CJ., Mulders, TM. Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring. Clin Pharmacokinet, 2000, 39, 3, p. 233-242.

Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account