Urinary tract infections


Authors: J. Vachek 1,2;  O. Zakiyanov 1,3;  V. Adámková 3;  V. Tesař 1
Authors‘ workplace: Klinika nefrologie VFN a 1. LF UK v Praze 1;  Farmakologický ústav 1. LF UK v Praze 2;  Ústav lékařské biochemie a laboratorní diagnostiky VFN a 1. LF UK v Praze 3
Published in: Kardiol Rev Int Med 2014, 16(1): 74-77
Category: Internal Medicine

Overview

Urinary tract infections are one of the most frequent clinical bacterial infections in adults. Escherichia coli is the organism that causes urinary tract infections in most patients. Consensus guidelines have been published to assist clinicians with dia­gnosis and treatment of urinary tract infection; however, a single evidence‑based approach to dia­gnosis of urinary tract infection does not exist. There is no gold-standard definition of urinary tract infection that clinicians agree upon. In a subgroup of individuals with coexisting morbid conditions, complicated urinary tract infections can lead to upper tract infections or urosepsis. Although the initial treatment is antimicrobial therapy, use of different prophylactic regimens and alternative strategies are available to reduce exposure to antibio­tics. Future studies improving the dia­gnostic accuracy of urinary tract infections are needed. This review will cover the prevalence, dia­gnosis and dia­gnostic challenges, management, and prevention of urinary tract infection and asymptomatic bacteriuria in adults.

Keywords:
asymptomatic bacteriuria –  antibio­tic treatment –  cystitis –  Enterobacteriaceae –  urinary infections –  pyelonephritis


Sources

1. Litwin MS, Saigal CS, Beerbohm EM. The burden of urologic diseases in America. J Urol 2005; 173: 1065– 1066.

2. Rüden H, Gastmeier P, Daschner FD et al. Nosocomial and community‑ acquired infections in Germany. Summary of the results of the First National Prevalence Study (NIDEP). Infection 1997; 25: 199– 202.

3. Naber KG, Schito G, Botto H et al. Surveillance study in Europe and Brazil on clinical aspects and Antimicrobial Resistance Epidemiology in Females with Cystitis (ARESC): implications for empiric therapy. Eur Urol 2008; 54: 1164– 1175.

4. Urbášková P, Jakubů V, Žemličková H et al. Rezistence k antibio­tikům u sedmi druhů invazivních bakterií, sledovaných v rámci EARSS v České republice v letech 2000– 2006. Prakt lék 2007; 87: 32– 38.

5. Bartoničková K, Bébrové E, Beneš J et al. Doporučený postup pro antibio­tickou léčbu komunitních infekcí ledvin a močových cest v primární péči. [online] Dostupné z: www.cls.cz/ dokumenty/ dp_imc.doc.

6. Gupta K, Hooton TM, Naber KG et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbio­logy and Infectious Diseases. Clin Infect Dis 2011; 52: e103– e120. doi: 10.1093/ cid/ ciq257.

7. Naber KG, Cho YH, Matsumoto T et al. Immunoactive prophylaxis of recurrent urinary tract infec­tions: a meta‑analysis. Int J Antimicrob Agents 2009; 33: 111– 119. doi: 10.1016/ j.ijantimicag.2008.08.011.

8. Piccoli GB, Consiglio V, Colla L et al. Antibio­tic treatment for acute 'uncomplicated' or 'primary' pyelonephritis: a systematic, 'semantic revision'. Int J Antimicrob Agents 2006; 28 (Suppl 1): S49– S63.

9. Grabe M, Bjerklund‑ Johansen TE, Botto H et al. Guidelines on Urological Infections. In (EDS). European Association of Urology Guidelines. Arnheim: EAU Guidelines Office 2011.

10. Vachek J, Tesař V, Zakiyanov O et al. Farmakoterapie v těhotenství a při kojení. Praha: Maxdorf 2013.

11. Toršová V, Chmelařová E. Antibio­tika v těhotenství. Interní Med 2001; 12: 550–552.

Labels
Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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