Metallothionen and Its General Importace in Carcinogenesis – Part 1

Authors: Z. Horáková;  E. Tóthová;  H. Binková;  R. Salzman;  P. Smilek
Authors‘ workplace: Klinika otorinolaryngologie a chirurgie hlavy a krku LF MU a FN u sv. Anny, Brno přednosta prof. MUDr. R. Kostřica, CSc.
Published in: Otorinolaryng. a Foniat. /Prague/, 57, 2008, No. 2, pp. 83-89.
Category: Comprehensive Reports


Metallothionein is a low-weight, intracellular, ubiquitously present protein of a characteristic structure. Its production can be induced by a wide range of physiologic and pathologic impulses. Its role in carcinogenesis has been intensively studied during the past few years. The following communication resumes basic information on its structure and function, and expression in various types of malignant tumors.

Key word:
metallothionein, carcinogenesis, tissue marker, head and neck tumor.


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Audiology Paediatric ENT ENT (Otorhinolaryngology)
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