Personalized medicine – genomic phase


Authors: R. Brdička
Authors‘ workplace: Ústav hematologie a krevní transfuze a Ústav experimentální medicíny AV ČR, Praha
Published in: Čas. Lék. čes. 2009; 148: 477-480
Category: Topic

Overview

Personalized medicine has become declared to be a strategic goal of nearly all medical disciplines, a modern fashion of medicine, which corresponds to unexpected progress in knowledge of structure and sometimes also understanding the function of our genome. This was made possible by development of new technologies and methodological approaches, which led to improved and more detailed diagnostics and categorization of diseases Also pharmaceutical industry is producing many new drugs, but not all are effective as supposed, and sometimes also cause adverse reactions (ADR). To prevent uneffectiveness and ADR, preliminary genetic testing of patients seems to be necessary. Utility of personalized medicine is sometimes discussed from the point of view of supposed inevitable increase of cost and problems with its adoption by existing system of healthcare.

Key words:
molecular diagnostics, interindividual differences, rare diseases, breast cancer, favism, pharmacogenomics, targeted therapy, adverse reactions, economics.


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Internetové adresy:

http://www.personalizedmedicinecoalition.org/

http://www.p3g.org/

http://www.p3gconsortium.org/

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
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