Spondylodiscitis – known and unknown


Authors: P. Polák 1;  E. Pernicová 1;  P. Husa 1;  Š. Bohatá 2;  A. Štouračová 2
Authors‘ workplace: Klinika infekčních chorob FN a LF MU Brno Přednosta: prof. MUDr. Petr Husa, CSc. 1;  Radiologická klinika FN a LF MU Brno Přednosta: prof. MUDr. Vlastimil Válek, CSc., MBA 2
Published in: Prakt. Lék. 2010; 90(9): 519-524
Category: Various Specialization

Overview

The infection of intervertebral disc and of the vertebral body is a disease associated with relatively high mortality and with a risk of severe long-lasting complications. Immobile and immunocompromised patients with metabolic complications represent the majority of predisposed persons. It is distinguished among spondylodiscitis of

– bacterial,

– fungal and

– parasitic origin.

Tuberculosis represents specific form of spondylodiscitis.

The diagnosis is often difficult – multiple diagnostic procedures have to be combined. The most sensitive and specific method is magnetic-resonance-imaging (MRI). The therapy of spondylodiscitis has to respect specifics of antibiotic pharmacokinetics into the bone tissue and has to be always elongated. At present, there exist no worldwide unified guidelines. In this article recent knowledge of aetiology, pathophysiology, diagnosis and therapy of spondylodiscitis are reviewed.

The aim of this article is to enhance medical staff awareness of this condition.

Key words:

spondylodiscitis, infection, pharmacotherapy.


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