In vitro fertilization – analysis of data in Czech National Assisted Reproduction Register from years 2007-2011


Authors: K. Řežábek
Authors‘ workplace: Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc. ;  Odborný garant Národního registru asistované reprodukce Ministerstva zdravotnictví České republiky
Published in: Čes. Gynek.2012, 77, č. 4 s. 336-341

Overview

Objective:
Analysis of IVF cycles (excluding donor oocytes programs) in Czech National Assisted Reproduction Register (NRAR).

Design:
Retrospective study.

Methods:
We analyzed NRAR data from 1. 1. 2007 to 31. 12. 2011 (107 529 cycles) concerning IVF cycles, according standards of European IVF monitoring – European Society of Human Reproduction and Embryology (EIM ESHRE).

Results:
Yearly in Czech Republic there is 10 000–14 000 initiated IVF cycles. In agreement with common experience, IVF results differ depending the age of woman. The completeness of data in NRAR decreases significantly during the cycle course; data concerning the delivery after the cycle are missing in more than 50% of cycles in some years. So, parameters of cycle effectiveness are not possible to evaluate yet.

Conclusion:
Number of IVF centers in Czech Republic is still growing.

Number of IVF cycles (and similarly frozen embryo transfer cycles) in Czech Republic is in general yearly very similar. In the subgroup of the age under 34, the number of cycles slightly diminishes, in the age group 34–40 increases.

Number of cycles in Oocyte donation cycles and in Oocyte reception cycles is increasing.

The effectiveness of IVF treatments is not possible to evaluate due to an important part of cycles with missing data concerning pregnancies and deliveries. It is necessary to stimulate centers to send missing data, but also to create the interconnection with the Deliveries register and the Abortions register, to reach data in cases, where it is really difficult to reach them by centers.

Key words:
register, assisted reproduction, IVF, effectiveness.


Sources

1. de Mouzon, J., et al. and The European IVF-monitoring (EIM) Consortium: Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE, Human Reproduction 2010. Viz: http://www.eshre.eu/binarydata.aspx?type =doc&sessionId=zpm0fx45kx0prf55zhaztzm5/De_Mouzon_2010_ART_in_Europe_2006,_results_generated_from_European_registers_by_ESHRE.pdf

2. Závazné pokyny NZIS – Národní registr asistované reprodukce- Pokyny k obsahu datové struktury, ÚZIS České republiky, 2010 http://www.uzis.cz/system/files/asist_reprod_062_20101001.pdf

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

Article was published in

Czech Gynaecology

Issue 4

2012 Issue 4

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