Clinical Outcome, Inflammatory Responseand Tissue Trauma in Total LaparoscopicHysterectomy: Comparison toLaparoscopically-assisted Vaginal Hysterectomy

Authors: Z. Holub 1;  A. Jabor 2;  L. Šprongl 3;  D. Fischlová 4;  Š. Urbánek 1
Authors‘ workplace: Department of Gynaecology and Obstetrics, Endoscopic Training Centre, Hospital Kladno 2Department of Biochemistry, Postgraduate Medicine School, Hospital Kladno 3Department of Biochemistry, Charles Univesity School of Medicine, Faculty Hospital Motol-Prag 1
Published in: Ceska Gynekol 2002; (6): 315-320


Our aim was quantify and compare the clinical outcome and surgical inflammatoryresponse and tissue trauma between the total laparoscopic hysterectomy (TLH) and laparoscopically-assisted vaginal hysterectomy (LAVH).Design: Clinical study.Setting: Departments of Gynaecology, Obstetrics and Biochemistry, Hospital Kladno, Departmentof Biochemistry, Faculty Hospital Motol-Prague.Methods: Fifty-eight patients scheduled for laparoscopic hysterectomy were selected accordingpatients or doctor preference to undergo either TLH or LAVH operative technique. Blood samplesfor assay of markers of tissue trauma (C-reactive protein, interleukin-6, creatine kinase, cortisol,cystatin C, serotonin and white blood cells count) were taken preopereatively, on the first andthird postoperative day. One patient with intraoperative complication (ureteral injury) was excludedfrom tissue analysis.Results: No differences were present in the demographic characteristics and clinical outcomes(blood loss, complications and hospital stay) in fifty seven laparoscopic hysterectomies. The statisticallysignificant difference was found only in duration of surgery (70 min in TLH group vs. 90min in LAVH group, P

Key words:
total laparoscopic hysterectomy, LAVH, inflammatory response, tissue trauma

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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

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Czech Gynaecology

2002 Issue 6

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