Reproductive Risks of Aging Males

Authors: T. Mardešić
Authors‘ workplace: Sanatorium Pronatal, vedoucí lékař doc. MUDr. T. Mardešić, CSc.
Published in: Ceska Gynekol 2002; (6): 371-375


To review the literature on the association between male age and semen quality, fertilitystatus and reproductive risks.Design: Review.Setting: Centre for infertility diagnosis and treatment Sanatorium Pronatal, Prague.Methods: Review of English language-published research over the last 20 years using MEDLINE.Results: The modification of gamete production in aging males is more qualitative than quantitative.However, aging of testes not only influences the individual, but through the gametes alsooffspring with increased risk of chromosomal, gene and behavioral abnormalities.Conclusion: It seems reasonable and consistent to recommend that both men and women completetheir family before age 40 if possible.

Key words:
age, cytogenetics, fecundity, fertility, chromosomal aberrations, male infertility, mentalfunctions, spermatogenesis

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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

Article was published in

Czech Gynaecology

2002 Issue 6

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